Eli Lilly and Company

1,341 total trials 124 currently recruiting 1029 completed

Eli Lilly and Company sponsors 1,341 registered US clinical trials on ClinicalTrials.gov, 124 of them currently recruiting, and 1,029 completed. 459 of these trials are in Phase 3-4 (later-stage) and 861 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 55 trials.

Trial Pipeline

1,341 total, page 3 of 27

RECRUITING

A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease

NCT06566170

RECRUITING Phase 1

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

NCT06561685

RECRUITING Phase 1

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

NCT06586515

RECRUITING Phase 1

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

NCT06297590

RECRUITING Phase 1

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT06465069

RECRUITING Phase 3

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

NCT06439277

RECRUITING Phase 1

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

NCT06400472

RECRUITING Phase 3

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

NCT06338995

RECRUITING Phase 3

A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)

NCT06339008

RECRUITING Phase 2

A Study of LY3541860 in Adult Participants With Relapsing Multiple Sclerosis

NCT06220669

RECRUITING Phase 3

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

NCT05509777

RECRUITING Phase 1

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

NCT06238479

RECRUITING Phase 3

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

NCT06119581

RECRUITING Phase 1

A Study of LY3971297 in Healthy Participants

NCT06148272

RECRUITING Phase 3

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis

NCT05784246

RECRUITING Phase 2

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

NCT06143956

RECRUITING Phase 2

An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

NCT05848258

RECRUITING Phase 1

First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

NCT05768139

RECRUITING Phase 3

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

NCT05723198

RECRUITING Phase 1

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

NCT05614739

RECRUITING Phase 1

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

NCT04956640

RECRUITING Phase 3

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

NCT04844606

RECRUITING Phase 2

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

NCT05986292

RECRUITING Phase 2

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

NCT05999994

ACTIVE NOT RECRUITING Phase 1

A Study of LY4064809 in Healthy Adult Participants

NCT07339735

ACTIVE NOT RECRUITING Phase 1

A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment

NCT07165015

ACTIVE NOT RECRUITING Phase 3

A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight

NCT06962280

ACTIVE NOT RECRUITING Phase 3

A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight

NCT06914895

ACTIVE NOT RECRUITING Phase 3

A Study to Investigate the Efficacy and Safety of Lebrikizumab in Participants With Moderate-to-Severe Atopic Hand and Foot Dermatitis

NCT06921759

ACTIVE NOT RECRUITING Phase 2

A Study of LY3541860 in Adult Participants With Moderately to Severely Active Rheumatoid Arthritis

NCT06859294

ACTIVE NOT RECRUITING Phase 3

A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With Obesity

NCT06859268

ACTIVE NOT RECRUITING Phase 1

A Study of LY4060874 in Healthy Participants

NCT06709820

ACTIVE NOT RECRUITING Phase 2

A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight

NCT06683508

ACTIVE NOT RECRUITING Phase 1

A Study of LY4005130 in Healthy Participants

NCT06690996

ACTIVE NOT RECRUITING Phase 3

A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity

NCT06662383

ACTIVE NOT RECRUITING Phase 2

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

NCT06413706

ACTIVE NOT RECRUITING Phase 3

A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

NCT06653153

ACTIVE NOT RECRUITING Phase 3

A Master Protocol for Orforglipron in Participants With Obstructive Sleep Apnea and Obesity or Overweight

NCT06649045

ACTIVE NOT RECRUITING Phase 2

A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight

NCT06643728

ACTIVE NOT RECRUITING Phase 1

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

NCT06607185

ACTIVE NOT RECRUITING Phase 3

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight

NCT06588283

ACTIVE NOT RECRUITING Phase 3

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight

NCT06588296

ACTIVE NOT RECRUITING Phase 2

A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes

NCT06603571

ACTIVE NOT RECRUITING Phase 1

A Study of LY3537031 in Overweight, Obese, and Healthy Participants

NCT06606106

ACTIVE NOT RECRUITING Phase 2

A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease

NCT06538116

ACTIVE NOT RECRUITING Phase 2

Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy

NCT06568042

ACTIVE NOT RECRUITING Phase 3

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)

NCT06383390

ACTIVE NOT RECRUITING Phase 2

A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity

NCT06373146

ACTIVE NOT RECRUITING Phase 3

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

NCT06297603

ACTIVE NOT RECRUITING Phase 3

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

NCT06292013

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Phase Distribution

PhaseTrial count
Phase 1 517
Phase 2 344
Phase 3 368
Phase 4 91

What the Pipeline for Eli Lilly and Company Shows

According to the ClinicalTrials.gov registry, Eli Lilly and Company is linked to 1,341 US clinical trials across every stage of research activity. Of those, 124 studies are currently recruiting, about 9% of the sponsor's indexed portfolio, and 1,029 are already marked complete, representing roughly 77% of the total.

The phase mix for Eli Lilly and Company reports 459 late-stage studies (Phase 3 and Phase 4 combined) and 861 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Eli Lilly and Company is Healthy with 55 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.