Eli Lilly and Company

704 total trials 382 currently recruiting 242 completed

Trial Pipeline

RECRUITING Phase 1

A Study of Olomorasib (LY3537982) in Healthy Participants

NCT07439250

RECRUITING Phase 1

A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function

NCT07426380

RECRUITING Phase 2

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain

NCT07285018

RECRUITING Phase 2

A Study of Brenipatide in Participants With Opioid Use Disorder

NCT07420283

RECRUITING Phase 3

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

NCT07369011

RECRUITING Phase 3

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

NCT07392190

RECRUITING Phase 1

A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

NCT07401862

RECRUITING Phase 3

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

NCT07353931

RECRUITING Phase 3

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

NCT07412756

RECRUITING Phase 3

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

NCT07321886

RECRUITING Phase 3

A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)

NCT07222332

RECRUITING Phase 3

A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight

NCT07357415

RECRUITING Phase 1

A Study of LY4515100 in Healthy Participants

NCT07339722

RECRUITING Phase 3

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

NCT07222137

RECRUITING Phase 3

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

NCT07174336

RECRUITING Phase 1

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

NCT07258836

RECRUITING Phase 3

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

NCT07282600

RECRUITING Phase 3

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

NCT07218380

RECRUITING Phase 2

A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia

NCT07269210

RECRUITING Phase 1

A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

NCT07258849

RECRUITING Phase 2

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

NCT07169851

RECRUITING Phase 2

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

NCT07286175

RECRUITING Phase 1

A Study of LY4167586 in Participants With Obesity or Overweight Who Are Otherwise Healthy

NCT07225556

RECRUITING Phase 3

A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight

NCT07232719

RECRUITING Phase 2

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

NCT07186101

RECRUITING Phase 2

A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

NCT07223840

RECRUITING Phase 3

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

NCT07223593

RECRUITING Phase 1

A Study of LY3549492 in Healthy Participants and Participants With Overweight or Obesity

NCT07232732

RECRUITING Phase 1

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

NCT07213791

RECRUITING Phase 2

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

NCT07219173

RECRUITING Phase 3

A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

NCT07213804

RECRUITING Phase 3

A Study of Brenipatide in Participants With Alcohol Use Disorder

NCT07219953

RECRUITING Phase 2

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

NCT07215559

RECRUITING Phase 3

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

NCT07165028

RECRUITING Phase 3

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

NCT07219966

RECRUITING Phase 2

A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin

NCT07215312

RECRUITING Phase 3

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

NCT07202884

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

NCT07153471

RECRUITING Phase 3

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

NCT07157774

RECRUITING Phase 1

A Study of LY4064912 in Healthy Participants and With Overweight or Obesity

NCT07152002

RECRUITING Phase 3

Epidemiology and Biomarker Study in Alzheimer's Disease

NCT07142954

RECRUITING NA

A Study Evaluating the Impact of P-tau217 Blood Biomarker Testing on Early Evaluation and Management of Patients Presenting With Cognitive Complaint

NCT07140744

RECRUITING Phase 1

A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function

NCT07137689

RECRUITING Phase 1

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT07114601

RECRUITING Phase 1

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

NCT06721013

RECRUITING Phase 1

A Study of LY4175408 in Participants With Advanced Cancer

NCT07046923

RECRUITING Phase 1

A Study of LY4088044 in Healthy Participants

NCT07090785

RECRUITING Phase 1

A Study of Multiple Olomorasib (LY3537982) Capsules in Healthy Participants

NCT07044271

RECRUITING Phase 3

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

NCT06937099

RECRUITING Phase 3

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

NCT06937086

RECRUITING Phase 4

A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden

NCT07006792

RECRUITING Phase 1

A Study of LY3981314 in Healthy Participants

NCT07005284

RECRUITING Phase 3

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

NCT07035093

RECRUITING Phase 1

A Study of LY3867070 in Healthy Participants

NCT07021547

RECRUITING Phase 4

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

NCT06876662

RECRUITING Phase 4

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

NCT06876649

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes

NCT06972472

RECRUITING Phase 3

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes

NCT06993792

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related Comorbidity

NCT06972459

RECRUITING Phase 1

A Study of LY4268989 (MORF-057) in Healthy Participants

NCT06964776

RECRUITING Phase 3

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1

NCT06948435

RECRUITING Phase 3

A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)

NCT06948422

RECRUITING Phase 3

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2

NCT06952530

RECRUITING Phase 1

A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes

NCT06945419

RECRUITING Phase 1

A Study of Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function

NCT06916078

RECRUITING Phase 1

Comparing the Extent to Which Three Different Formulations of LY4100511 (DC-853) Are Made Available in the Body, Alone and in the Presence of a Drug That Reduces Stomach Acid

NCT06916143

RECRUITING Phase 2

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

NCT06897475

RECRUITING Phase 3

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT06890598

RECRUITING Phase 4

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

NCT06857942

RECRUITING Phase 4

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

NCT06864026

RECRUITING Phase 1

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

NCT06809400

RECRUITING Phase 2

A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder

NCT06817356

RECRUITING Phase 3

A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

NCT06739122

RECRUITING Phase 3

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

NCT06672549

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

NCT06672939

RECRUITING Phase 1

A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

NCT06657768

RECRUITING Phase 2

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

NCT06598943

RECRUITING Phase 1

A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus

NCT06362265

RECRUITING

A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease

NCT06566170

RECRUITING Phase 1

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

NCT06561685

RECRUITING Phase 1

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

NCT06586515

RECRUITING Phase 1

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

NCT06297590

RECRUITING Phase 1

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

NCT06465069

RECRUITING Phase 3

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

NCT06439277

RECRUITING Phase 1

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

NCT06400472

RECRUITING Phase 3

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

NCT06338995

RECRUITING Phase 3

A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)

NCT06339008

RECRUITING Phase 2

A Study of LY3541860 in Adult Participants With Relapsing Multiple Sclerosis

NCT06220669

RECRUITING Phase 3

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

NCT05509777

RECRUITING Phase 1

A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

NCT06238479

RECRUITING Phase 3

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

NCT06119581

RECRUITING Phase 1

A Study of LY3971297 in Healthy Participants

NCT06148272

RECRUITING Phase 3

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis

NCT05784246

RECRUITING Phase 2

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

NCT06143956

RECRUITING Phase 2

An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

NCT05848258

RECRUITING Phase 1

First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

NCT05768139

RECRUITING Phase 3

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata

NCT05723198

RECRUITING Phase 1

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

NCT05614739

RECRUITING Phase 1

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

NCT04956640

RECRUITING Phase 3

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

NCT04844606

Phase Distribution

PhaseTrial count
Phase 1 319
Phase 2 95
Phase 3 230
Phase 4 52

What the Pipeline for Eli Lilly and Company Shows

According to the ClinicalTrials.gov registry, Eli Lilly and Company is linked to 704 US clinical trials across every stage of research activity. Of those, 382 studies are currently recruiting — about 54% of the sponsor's indexed portfolio — and 242 are already marked complete, representing roughly 34% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Eli Lilly and Company reports 282 late-stage studies (Phase 3 and Phase 4 combined) and 414 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Eli Lilly and Company is Healthy with 55 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial