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NCT06148272 · ClinicalTrials.gov registry record · Phase 1
A Study of LY3971297 in Healthy Participants
A Phase 1 study of Healthy and Obesity, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 225
- Enrollment target
- 7
- Study locations
NCT06148272: Recruiting Phase 1 study of Healthy and Obesity, sponsored by Eli Lilly and Company.
NCT06148272 is a Phase 1 study of Healthy and Obesity that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 225 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (65% lower). The trial reports 7 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06148272, a Phase 1 study of Healthy and Obesity, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 225 participants
- Enrollment target
- 7
- Study locations
Study Summary
The purpose of this study is to measure side effects of LY3971297 injection administered under the skin in healthy participants and obese participants with high blood pressure (BP). Blood tests will be performed to check how much LY3971297 gets into the bloodstream and how long it takes the body to eliminate it. This is a 7-part study. The study duration will be approximately 60 days for Parts A and F, and approximately 90 days for Parts B, C, D, E, and G.
Primary Outcome
Part A and F: A summary of TEAEs and SAEs, regardless of causality, will be reported in the Reported Adverse Events module
Conditions Studied
Interventions
- DRUG Placebo
- DRUG LY3971297
- DRUG LY3971297 IV
Study Locations (7)
Other
- Hakata Clinic - Fukuoka
- P-One Clinic - Hachiōji
- Clinical Research Hospital Tokyo - Shinjuku-ku
- Lilly Centre for Clinical Pharmacology - Singapore
California
- CenExel ACT - Anaheim
Florida
- Clinical Pharmacology of Miami - Miami
Texas
- ICON Early Phase Services - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 225 participants |
| Start Date | 2023-12-07 |
| Est. Completion | 2026-09 |
| Phase | Phase 1 |
What NCT06148272 shows while recruiting
NCT06148272 is an interventional study that assigns participants to a tested intervention. The registered 225 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (65% lower).
The record links to 3 conditions, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT06148272 lists 7 locations in 4 states (Other, California, Florida).
Frequently Asked Questions
What is clinical trial NCT06148272 about?
NCT06148272 is a clinical study titled "A Study of LY3971297 in Healthy Participants". The purpose of this study is to measure side effects of LY3971297 injection administered under the skin in healthy participants and obese participants with high blood pressure (BP). Blood tests will be performed to check how much LY3971297 gets into the bloodstream and how long it takes the body to ...
What is the current status of trial NCT06148272?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 225 participants. The study started on 2023-12-07. Estimated completion is 2026-09.
What conditions does trial NCT06148272 study?
This clinical trial studies the following conditions: Healthy, Obesity, Hypertension.
What interventions are being tested in trial NCT06148272?
The interventions under investigation include: Placebo (DRUG), LY3971297 (DRUG), LY3971297 IV (DRUG).
Who is sponsoring clinical trial NCT06148272?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06148272 being conducted?
This trial has 7 study locations across California, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06148272's enrollment target sits among peer trials
225 109th of 1090 higher than 981 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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