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Type 2 Diabetes: full-pipeline trial registry
103 of 289 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #30 of 28,963 conditions by registered trial count.
289 US clinical trials · 103 currently recruiting · #30 of 28,963 conditions by registered trial count
Type 2 Diabetes: 289 US clinical trials tracked, 103 recruiting.
Type 2 Diabetes is the subject of 289 registered US clinical trials on ClinicalTrials.gov, 103 of them currently open to new participants. 56 are in Phase 3-4 (later-stage) and 42 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Open enrollment snapshot
Type 2 Diabetes has 289 registered US clinical trials, 103 of them open to new participants right now, about 36% of the total.
- 103
- recruiting participants now
- 36%
- of trials open to enrollment
- 56
- in Phase 3-4 (later-stage)
- 20
- top sponsor: Eli Lilly and Company
Corpus placement: #30 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
103 of 289 indexed trials (35.6%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 289 trials (6.9%). 140 distinct sponsors appear on at least one study for this condition label.
-
Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 289 trials that report a genuine target (sentinel values excluded). 145 of those (50.2%) plan for fewer than 100 participants.
-
Type 2 Diabetes research is mostly interventional.
257 interventional and 32 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
289 total, page 1 of 6
'Ai Pono Cooking Demonstrations
University of Hawaii
NCT06526650
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Sparrow Pharmaceuticals
NCT07296484
A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes
Eli Lilly and Company
NCT06993792
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT06730113
Military Health and Nutrition Examination Study
Pennington Biomedical Research Center
NCT06380322
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes
Eli Lilly and Company
NCT06972472
Leveraging Videos and Community Health Workers to Address Social Determinants of Health in Immigrants
NYU Langone Health
NCT06319716
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Johns Hopkins University
NCT05463289
Enhancing Preventative Health Behaviors Among Emergency Department Hyperglycemic Patients
Rutgers, The State University of New Jersey
NCT06663813
Latinos Understanding the Need for Adherence in Diabetes Using E-Health
San Diego State University
NCT05570734
Novel Digital Patient-Reported Outcomes Tool for Diabetes Management
NYU Langone Health
NCT05884775
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Ohio State University
NCT06055036
NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study
University of Texas Southwestern Medical Center
NCT06593327
Gut Microbiota in Metabolic Surgery
Vanderbilt University Medical Center
NCT05000996
Implementing an Effective Diabetes Intervention Among Low-Income Immigrants
NYU Langone Health
NCT06319703
Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes
Endogenex
NCT06267391
Effectiveness of the Diabetes Homeless Medication Support (D-HOMES) Program on Diabetes Management
Katherine Vickery
NCT07091487
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Eli Lilly and Company
NCT06897475
Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
University of Colorado, Denver
NCT07011147
The GRoceries Aimed at Increasing Nutrition Study
University of Pennsylvania
NCT07167004
PILI 'Āina Household
University of Hawaii
NCT06526273
A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes
Eli Lilly and Company
NCT06945419
Diabetes Electronic Prompt for Improved Care Coordination and Treatment in the ED
Rutgers, The State University of New Jersey
NCT06899191
Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification
Chiara Fabris, PhD
NCT05766735
More Fresh Fruit and Vegetable Prescription Program for Families With Type 2 Diabetes Mellitus
University of California, San Diego
NCT05138432
Polypill for Prevention of Cardiomyopathy
University of Texas Southwestern Medical Center
NCT06143566
Food and Fitness With Medicine (FFWM)
Ohio State University
NCT07027995
Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
University of Michigan
NCT06007404
Implementation of Team Clinic for Type 2 Diabetes (TCT2)
Children's Hospital Los Angeles
NCT06923046
Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes
University of Colorado, Denver
NCT04791371
Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
Duke University
NCT05129345
Diabetes Reversal Online Program and Study (DROP Study)
Physicians Committee for Responsible Medicine
NCT05572502
Health Without Barriers/Salud Sin Barreras- Northern Colorado
Colorado State University
NCT06822387
GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
Massachusetts General Hospital
NCT06003153
Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease
Brigham and Women's Hospital
NCT06190158
The Diabetes Staging System in Patient Aligned Care Teams
Durham VA Medical Center
NCT06142006
Outcomes of Physiologic Insulin Resensitization (PIR) in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus
Well Cell Global
NCT07187479
Preventing T2DM After GDM With Immediate Postpartum Screening
University of Massachusetts, Worcester
NCT06457139
Time-restricted Eating for Patients With Type 2 Diabetes
Justin (Matt) Thomas
NCT07318207
Time Limited Eating in Adolescents With Type 2 Diabetes (KT2D)
Children's Hospital Los Angeles
NCT04536480
Assessing the Efficacy of Targeted Home Visits in the Management of Chronic Conditions
University of Texas Southwestern Medical Center
NCT05168605
Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes
Medical College of Wisconsin
NCT06279637
Diabetes Education/Skills Training and Social Needs Resolution Intervention
Medical College of Wisconsin
NCT05935410
My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes
University of Illinois at Chicago
NCT05208164
Sleep and Glycemic Control in Type 2 Diabetes Adolescents
Children's Hospital of Philadelphia
NCT04213547
Digital Health Navigation for Latino Patients With Type II Diabetes
Brigham and Women's Hospital
NCT06283992
Mechanisms of Fatigability With Diabetes
University of Michigan
NCT04442451
New T-UP: Engaging Vulnerable Students in Diabetes Prevention
University of California, Los Angeles
NCT07225218
IH, Brain Health, and T2D
Darren P Casey
NCT07173543
Effect of Meal Composition and Timing Modification on Glucose Metabolism, Body Temperature and Sleep
Stanford University
NCT05413928
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 21 |
| Phase 2 | 21 |
| Phase 3 | 34 |
| Phase 4 | 22 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Type 2 Diabetes right now
103 recruiting of 289 indexed (36% open).
Phase mix: 56 late (III/IV) vs 42 early (I/II) (balanced across stages).
Top sponsor: Eli Lilly and Company (20 trials), 9 others listed. 50 shown below, recruiting first. #30 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Type 2 Diabetes?
PlainTrial tracks 289 US clinical trials for Type 2 Diabetes, of which 103 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Type 2 Diabetes?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.