Shionogi
Shionogi sponsors 54 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 43 completed. 10 of these trials are in Phase 3-4 (later-stage) and 42 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy Volunteers, with 3 trials.
Trial Pipeline
54 total, page 1 of 2
A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease
NCT07214571
Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)
NCT07123155
A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls
NCT07217886
Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants
NCT07093580
S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Tumors
NCT05101070
Study of Zatolmilast (BPN14770) in Participants With PPP2R5D Neurodevelopmental Disorder (Jordan's Syndrome [JS])
NCT06717438
A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke
NCT05953480
Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls
NCT07018492
Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls
NCT07012005
A Study to Assess the Effects of BPN14770 on Rosuvastatin
NCT07011992
A Study of S-892216 in Participants With COVID-19
NCT06928051
A Drug-Drug Interaction Study of S-217622 With Combined Oral Contraceptives in Healthy Adult Female Participants
NCT06775730
A Drug-drug Interaction Study of S-892216 Coadministered With Carbamazepime to Healthy Adult Participants
NCT06751017
A Study to Investigate How Respiratory Syncytial Virus (RSV) Infection Develops and Changes Over Time in Pediatric Participants
NCT06746051
A Study of S-740792 in Healthy Adult Study Participants
NCT06724978
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants
NCT06086626
A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants
NCT06270511
Effect of Administration of Itraconazole on the Pharmacokinetics of S-309309 in Healthy Participants
NCT06106334
Safety and Efficacy Study of S-309309 in Obese Adults
NCT05925114
Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection
NCT05897541
A Study to Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants
NCT05409911
A Study to Assess S-217622 in Participants With Renal Impairment and Healthy Participants
NCT05363215
A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19
NCT05305547
A Study to Assess the Effect of Cefiderocol on the Pharmacokinetics (PK) of Midazolam in Healthy Participants
NCT05395104
A Study to Assess S-309309 in Healthy and Obese Participants
NCT05247970
A Study of Naldemedine in Participants Undergoing Surgeries That Include a Bowel Resection or Bowel Transection
NCT04355169
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants
NCT04215991
Evaluation of S-600918 in Adults With Refractory Chronic Cough
NCT04110054
Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)
NCT04259255
Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults
NCT04147715
Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia
NCT03862040
Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens
NCT03032380
Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens
NCT02714595
Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation
NCT01993940
Long Term Safety of Naldemedine
NCT01965652
Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation
NCT01965158
A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy
NCT01443403
Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Metformin Therapy
NCT01240759
Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus
NCT01154348
Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic Pain
NCT01122030
An Open-label Safety Study of Lusutrombopag (S-888711) in Adults With Chronic Immune Thrombocytopenia (ITP)
NCT01129024
Double-Blind, Multi-Center, Randomized Study to Assess the Efficacy and Safety of Velneperit (S-2367) and Orlistat Administered Individually or Combined With a Reduced Calorie Diet (RCD) in Obese Subjects
NCT01126970
A Study to Investigate the Efficacy and Safety of Lusutrombopag (S-888711) Tablets Administered to Adults With Immune Thrombocytopenia (ITP)
NCT01054443
Effect of Food and Calcium on Pharmacokinetics of a Single Dose of S-888711 in Healthy Adult Volunteers
NCT03897413
Open-Label Extension (OLE) Study for Safety and Efficacy of Velneperit (S-2367) in Obese Subjects
NCT00788528
A Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis
NCT00703573
Open-Label, Chronic Exposure, Safety Study of CLONICEL (Clonidine HCl Sustained Release) in Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD)
NCT00723190
A Phase Ib/IIa, Double-Blind, Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of S-777469 in Subjects With Atopic Dermatitis
NCT00697710
Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Initial 6-Week Low Calorie Diet
NCT00748605
Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Reduced Calorie Diet
NCT00747929
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 22 |
| Phase 2 | 20 |
| Phase 3 | 10 |
Therapeutic Areas
What the Pipeline for Shionogi Shows
According to the ClinicalTrials.gov registry, Shionogi is linked to 54 US clinical trials across every stage of research activity. Of those, 5 studies are currently recruiting, about 9% of the sponsor's indexed portfolio, and 43 are already marked complete, representing roughly 80% of the total.
The phase mix for Shionogi reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 42 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Shionogi is Healthy Volunteers with 3 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.