Shionogi

54 total trials 5 currently recruiting 43 completed

Shionogi sponsors 54 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 43 completed. 10 of these trials are in Phase 3-4 (later-stage) and 42 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy Volunteers, with 3 trials.

Trial Pipeline

54 total, page 1 of 2

RECRUITING Phase 2

A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease

NCT07214571

RECRUITING Phase 2

Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

NCT07123155

RECRUITING Phase 1

A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls

NCT07217886

RECRUITING Phase 1

Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants

NCT07093580

RECRUITING Phase 1

S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metastatic Solid Tumors

NCT05101070

ACTIVE NOT RECRUITING Phase 2

Study of Zatolmilast (BPN14770) in Participants With PPP2R5D Neurodevelopmental Disorder (Jordan's Syndrome [JS])

NCT06717438

ACTIVE NOT RECRUITING Phase 2

A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke

NCT05953480

COMPLETED Phase 1

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

NCT07018492

COMPLETED Phase 1

Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls

NCT07012005

COMPLETED Phase 1

A Study to Assess the Effects of BPN14770 on Rosuvastatin

NCT07011992

COMPLETED Phase 2

A Study of S-892216 in Participants With COVID-19

NCT06928051

COMPLETED Phase 1

A Drug-Drug Interaction Study of S-217622 With Combined Oral Contraceptives in Healthy Adult Female Participants

NCT06775730

COMPLETED Phase 1

A Drug-drug Interaction Study of S-892216 Coadministered With Carbamazepime to Healthy Adult Participants

NCT06751017

COMPLETED

A Study to Investigate How Respiratory Syncytial Virus (RSV) Infection Develops and Changes Over Time in Pediatric Participants

NCT06746051

COMPLETED Phase 1

A Study of S-740792 in Healthy Adult Study Participants

NCT06724978

COMPLETED Phase 2

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants

NCT06086626

COMPLETED Phase 1

A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants

NCT06270511

COMPLETED Phase 1

Effect of Administration of Itraconazole on the Pharmacokinetics of S-309309 in Healthy Participants

NCT06106334

COMPLETED Phase 2

Safety and Efficacy Study of S-309309 in Obese Adults

NCT05925114

COMPLETED Phase 3

Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection

NCT05897541

COMPLETED Phase 1

A Study to Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants

NCT05409911

COMPLETED Phase 1

A Study to Assess S-217622 in Participants With Renal Impairment and Healthy Participants

NCT05363215

COMPLETED Phase 3

A Study to Compare S-217622 With Placebo in Non-Hospitalized Participants With COVID-19

NCT05305547

COMPLETED Phase 1

A Study to Assess the Effect of Cefiderocol on the Pharmacokinetics (PK) of Midazolam in Healthy Participants

NCT05395104

COMPLETED Phase 1

A Study to Assess S-309309 in Healthy and Obese Participants

NCT05247970

TERMINATED Phase 2

A Study of Naldemedine in Participants Undergoing Surgeries That Include a Bowel Resection or Bowel Transection

NCT04355169

COMPLETED Phase 2

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants

NCT04215991

COMPLETED Phase 2

Evaluation of S-600918 in Adults With Refractory Chronic Cough

NCT04110054

COMPLETED

Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)

NCT04259255

COMPLETED Phase 1

Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy Adults

NCT04147715

TERMINATED Phase 1

Cefiderocol Concentrations in the Lungs of Hospitalized Patients With Bacterial Pneumonia

NCT03862040

COMPLETED Phase 3

Clinical Study of Cefiderocol (S-649266) for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens

NCT03032380

COMPLETED Phase 3

Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens

NCT02714595

COMPLETED Phase 3

Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation

NCT01993940

COMPLETED Phase 3

Long Term Safety of Naldemedine

NCT01965652

COMPLETED Phase 3

Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation

NCT01965158

COMPLETED Phase 2

A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy

NCT01443403

COMPLETED Phase 2

Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Metformin Therapy

NCT01240759

COMPLETED Phase 1

Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus

NCT01154348

COMPLETED Phase 2

Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic Pain

NCT01122030

TERMINATED Phase 2

An Open-label Safety Study of Lusutrombopag (S-888711) in Adults With Chronic Immune Thrombocytopenia (ITP)

NCT01129024

COMPLETED Phase 2

Double-Blind, Multi-Center, Randomized Study to Assess the Efficacy and Safety of Velneperit (S-2367) and Orlistat Administered Individually or Combined With a Reduced Calorie Diet (RCD) in Obese Subjects

NCT01126970

TERMINATED Phase 2

A Study to Investigate the Efficacy and Safety of Lusutrombopag (S-888711) Tablets Administered to Adults With Immune Thrombocytopenia (ITP)

NCT01054443

COMPLETED Phase 1

Effect of Food and Calcium on Pharmacokinetics of a Single Dose of S-888711 in Healthy Adult Volunteers

NCT03897413

COMPLETED Phase 2

Open-Label Extension (OLE) Study for Safety and Efficacy of Velneperit (S-2367) in Obese Subjects

NCT00788528

COMPLETED Phase 2

A Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis

NCT00703573

COMPLETED Phase 3

Open-Label, Chronic Exposure, Safety Study of CLONICEL (Clonidine HCl Sustained Release) in Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD)

NCT00723190

COMPLETED Phase 1

A Phase Ib/IIa, Double-Blind, Randomized Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of S-777469 in Subjects With Atopic Dermatitis

NCT00697710

COMPLETED Phase 2

Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Initial 6-Week Low Calorie Diet

NCT00748605

COMPLETED Phase 2

Phase IIb One Year Efficacy and Safety Study of S-2367 in Obese Subjects With Reduced Calorie Diet

NCT00747929

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What the Pipeline for Shionogi Shows

According to the ClinicalTrials.gov registry, Shionogi is linked to 54 US clinical trials across every stage of research activity. Of those, 5 studies are currently recruiting, about 9% of the sponsor's indexed portfolio, and 43 are already marked complete, representing roughly 80% of the total.

The phase mix for Shionogi reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 42 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Shionogi is Healthy Volunteers with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.