Browse All Conditions

Explore 28,708 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov. According to ClinicalTrials.gov, the NIH registry maintained by the National Library of Medicine contains more than 500,000 studies in more than 220 countries. The 2007 FDAAA requires registration for most FDA-regulated studies. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1,251Healthy1,096Obesity1,057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer455
A2,809B1,091C2,928D1,168E986F825G765H1,701I1,106J82K187L1,231M2,114N1,012O820P2,801Q24R1,691S3,009T967U528V509W238X47Y19Z17
Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer 1,251 Healthy 1,096 Obesity 1,057 Prostate Cancer 749 Depression 687 Cancer 621 HIV Infections 615 Hypertension 472 Stroke 456 Non-Small Cell Lu… 455

28,708 conditions

Sort by: Name Most Trials Recruiting
Condition Trials
1 Fluid Management 1
1 Paravisceral Abdominal Aortic Aneurysm 1
1. Obesity 1
13-valent Pneumococcal Vaccine 1
160 Participants Aged 18-35 Years and Obese (BMI ≥30) Open to Men and Women of All Ethnicity 1
16P11.2 Deletion Syndrome 2
16p11.2 Duplications 1
1Q21.1 Deletion 1
1Q21.1 Microduplication Syndrome (Disorder) 1
1st Degree Burn of the Skin 1
1st Line NSCLC 1
2 Juxtarenal Abdominal Aortic Aneurysm 1
21-Hydroxylase Deficiency 3
22Q11 Deletion Syndrome 1
22q11.2 Deletion Syndrome 1
24-Hour Movement Guidelines 1
24-hydroxylase Deficiency 1
2L+ Cervical Cancer 1
2nd Degree Burn of the Skin 1
2nd-line, 3rd-line and Greater Metastatic Pancreatic Cancer 1
3 Pararenal Abdominal Aortic Aneurysm 1
3D Printing 2
3D Sonography 1
3rd Degree Burn of the Skin 1
3rd Line GIST 1
4 Complex Abdominal Aortic Aneurysms 1
47,XXY 1
4H Syndrome 1
5q Minus Syndrome 1
9p Minus Syndrome 1
9P Monosomy 1
9P Partial Monosomy Syndrome 1
A Diagnosis of Any Hematologic or Solid Malignancy 1
a Diagnosis of MGUS or SMM by IMWG Criteria 1
A Healthcare Professional, a Patient or Caregiver in the Radiation Oncology Department at the University of Pennsylvania 1
A. Longitudinal Cohort n=400 1
AAA 1
AAA - Abdominal Aortic Aneurysm 2
AADC Deficiency 2
AAT Deficiency 1
AATD 1
AB Variant Gangliosidosis GM2 1
Abacterial Chronic Prostatitis/Chronic Pelvic Pain Syndrome 1
ABCA4 Retinopathy 1
ABCA4-Related Retinopathies 1
Abdomen Hernia 1
Abdomen Injury 1
Abdomen, Acute 1
Abdominal Abscess 1
Abdominal Aortic Aneurysm 17

Download the state trial statistics CSV cited on this page: clinicaltrials-gov-us-state-statistics.csv (ClinicalTrials.gov · CC0).