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ClinicalTrials.gov 10 recruiting now early-phase tilt

Neoplasm Metastasis: early-phase trial registry

10 of 42 indexed Neoplasm Metastasis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #347 of 28,707 conditions by registered trial count.

42 US clinical trials · 10 currently recruiting · #347 of 28,707 conditions by registered trial count

Neoplasm Metastasis: 42 US clinical trials tracked, 10 recruiting.

Neoplasm Metastasis is the subject of 42 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 15 of these trials.

Enrollment posture brief

Registry condition neoplasm-metastasis

OPEN 10 | RECR 24% | LATE 9 | EARLY 28 | RANK #347 | SPON 15

Nearest open-share peer: Dehydration (24% recruiting · 21 trials)

Gestational Diabetes64.3%Essential Tremor57.1%Epithelial Ovarian Cancer42.9%Neoplasm Metastasis (this)24%Dry Eye21.4%
Open-enrollment share among volume-matched conditions near Neoplasm Metastasis

Neoplasm Metastasis lists 10 open slots (24% of 42 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Neoplasm Metastasis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Neoplasm Metastasis is recruiting below its size-band peers.

    10 of 42 indexed trials (23.8%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Neoplasm Metastasis research.

    Eli Lilly and Company accounts for 15 of 42 trials (35.7%). 21 distinct sponsors appear on at least one study for this condition label.

  3. Typical Neoplasm Metastasis enrolment sits around 152 participants.

    Median target enrolment is 152 among the 42 trials that report a genuine target (sentinel values excluded). 17 of those (40.5%) plan for fewer than 100 participants.

  4. Neoplasm Metastasis research is mostly interventional.

    39 interventional and 3 observational studies make up this index (92.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 119Phase 29Phase 38Phase 41

Open and recent trials

42 total, page 1 of 1

RECRUITING Phase 3 1,264 participants

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Eli Lilly and Company

NCT06119581

RECRUITING Phase 3 1,080 participants

A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

Eli Lilly and Company

NCT07213804

RECRUITING Phase 3 920 participants

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Eli Lilly and Company

NCT07174336

RECRUITING Phase 1 535 participants

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Eli Lilly and Company

NCT05614739

RECRUITING Phase 3 450 participants

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Eli Lilly and Company

NCT07218380

RECRUITING Phase 1 421 participants

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

Eli Lilly and Company

NCT07114601

RECRUITING Phase 1 240 participants

A Study of LY4175408 in Participants With Advanced Cancer

Eli Lilly and Company

NCT07046923

RECRUITING Phase 1 152 participants

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

Shanghai EpimAb Biotherapeutics Co.

NCT05176665

RECRUITING NA 60 participants

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

Henry Ford Health System

NCT05023772

RECRUITING Phase 1 36 participants

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

University of Chicago

NCT06912087

ACTIVE NOT RECRUITING Phase 3 925 participants

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)

Eli Lilly and Company

NCT05288166

ACTIVE NOT RECRUITING Phase 3 874 participants

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

Eli Lilly and Company

NCT04975308

ACTIVE NOT RECRUITING Phase 2 720 participants

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

Genentech

NCT00781612

ACTIVE NOT RECRUITING Phase 1 608 participants

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

Boehringer Ingelheim

NCT04886804

ACTIVE NOT RECRUITING Phase 3 368 participants

Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer

Eli Lilly and Company

NCT05169567

ACTIVE NOT RECRUITING Phase 2 350 participants

9-ING-41 in Patients with Advanced Cancers

Actuate Therapeutics

NCT03678883

ACTIVE NOT RECRUITING Phase 1 168 participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Merck Sharp & Dohme

NCT06460961

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING Phase 2 46 participants

CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Eli Lilly and Company

NCT05440786

ACTIVE NOT RECRUITING 18 participants

Hepatic Resection for Metastatic Pancreatic Cancer

Duke University

NCT02892305

COMPLETED 2,579 participants

Analyses of Human Samples Collected in Clinical Trials

National Cancer Institute (NCI)

NCT00339664

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED Phase 3 1,224 participants

Aflibercept in Combination With Docetaxel in Metastatic Androgen Independent Prostate Cancer

Sanofi

NCT00519285

COMPLETED Phase 1 170 participants

A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer

Eli Lilly and Company

NCT01373164

COMPLETED Phase 2 170 participants

Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma

National Cancer Institute (NCI)

NCT00001832

COMPLETED Phase 1 167 participants

A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer

Eli Lilly and Company

NCT02124148

COMPLETED Phase 4 130 participants

Surgery Versus Radiosurgery to Treat Metastatic Brain Tumors

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00075166

COMPLETED Phase 1 120 participants

An Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastatic Non Small Cell Lung Carcinoma

Eli Lilly and Company

NCT00207116

COMPLETED Phase 1 107 participants

Chemotherapy and Progenitor Cell Transplantation to Treat Inflammatory Breast Cancer

National Cancer Institute (NCI)

NCT00001507

COMPLETED Phase 1 80 participants

A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases

AbbVie (prior sponsor, Abbott)

NCT00649207

COMPLETED Phase 1 80 participants

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

National Cancer Institute (NCI)

NCT00001302

COMPLETED Phase 2 60 participants

Oxaliplatin, Capecitabine and Avastin for Metastatic Esophagogastric Adenocarcinoma

Duke University

NCT00447330

COMPLETED Phase 1 51 participants

Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy

National Cancer Institute (NCI)

NCT00001440

COMPLETED Phase 1 46 participants

A Phase I Study of Continuous Intravenous Infusion of PSC 833 and Vinblastine in Patients With Metastatic Renal Cancer

National Cancer Institute (NCI)

NCT00001570

COMPLETED Phase 2 43 participants

Use of Cetuximab for Unresectable or Metastatic Esophageal and Gastric Cancer

Dana-Farber Cancer Institute

NCT00130689

COMPLETED Phase 2 36 participants

Cetuximab Plus Biweekly Capecitabine and Oxaliplatin in KRAS Wild Type Metastatic Colorectal Cancer

NYU Langone Health

NCT00444678

COMPLETED Phase 2 32 participants

Tarceva and Capecitabine for Pancreatic Cancer

Dana-Farber Cancer Institute

NCT00125021

COMPLETED Phase 1 26 participants

A Study of LY2835219 in Participants With Cancer

Eli Lilly and Company

NCT02117648

COMPLETED 25 participants

Study of Resection Combined With Stereotactic Radiosurgery for 1 to 3 Brain Metastases

University of Rochester

NCT00904553

COMPLETED Phase 1 17 participants

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Stanford University

NCT00946673

COMPLETED Phase 1 9 participants

Study of Safety and Tolerability of Intravenous CRS-100 in Adults With Carcinoma and Liver Metastases

Anza Therapeutics

NCT00327652

COMPLETED Phase 1 8 participants

Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases

University of California, San Diego

NCT01114958

Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 9
Phase 3 8
Phase 4 1

Named interventions

Most-linked intervention names on Neoplasm Metastasis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Abemaciclib Drug
6 trials
Cetuximab Drug
5 trials
Placebo Drug
4 trials
Pembrolizumab Drug
4 trials
PSC 833 Drug
2 trials
Prednisone or Prednisolone Drug
2 trials
Gemcitabine Drug
2 trials
Fulvestrant Drug
2 trials

US sites by state

Facility locations filed on Neoplasm Metastasis trials. A trial with sites in several states counts in each.

California 17 trials
Florida 16 trials
Arizona 11 trials
Maryland 10 trials
Illinois 10 trials
Texas 7 trials
New York 7 trials
Georgia 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Neoplasm Metastasis page

42 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Neoplasm Metastasis condition card totals 42 registered trials; most-linked intervention Abemaciclib; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.