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2026 data Public-data reference. official source

Neoplasm Metastasis

Open-data reference.

42 US clinical trials · 10 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 1,264 participants

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Eli Lilly and Company

NCT06119581

RECRUITING Phase 3 1,080 participants

A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

Eli Lilly and Company

NCT07213804

RECRUITING Phase 3 920 participants

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Eli Lilly and Company

NCT07174336

RECRUITING Phase 1 535 participants

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Eli Lilly and Company

NCT05614739

RECRUITING Phase 3 450 participants

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Eli Lilly and Company

NCT07218380

RECRUITING Phase 1 421 participants

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

Eli Lilly and Company

NCT07114601

RECRUITING Phase 1 240 participants

A Study of LY4175408 in Participants With Advanced Cancer

Eli Lilly and Company

NCT07046923

RECRUITING Phase 1 152 participants

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

Shanghai EpimAb Biotherapeutics Co.

NCT05176665

RECRUITING NA 60 participants

Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

Henry Ford Health System

NCT05023772

RECRUITING Phase 1 36 participants

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

University of Chicago

NCT06912087

ACTIVE NOT RECRUITING Phase 3 925 participants

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)

Eli Lilly and Company

NCT05288166

ACTIVE NOT RECRUITING Phase 3 874 participants

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

Eli Lilly and Company

NCT04975308

ACTIVE NOT RECRUITING Phase 2 720 participants

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

Genentech

NCT00781612

ACTIVE NOT RECRUITING Phase 1 608 participants

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

Boehringer Ingelheim

NCT04886804

ACTIVE NOT RECRUITING Phase 3 368 participants

Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer

Eli Lilly and Company

NCT05169567

ACTIVE NOT RECRUITING Phase 2 350 participants

9-ING-41 in Patients with Advanced Cancers

Actuate Therapeutics

NCT03678883

ACTIVE NOT RECRUITING Phase 1 168 participants

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Merck Sharp & Dohme

NCT06460961

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING Phase 2 46 participants

CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Eli Lilly and Company

NCT05440786

ACTIVE NOT RECRUITING 18 participants

Hepatic Resection for Metastatic Pancreatic Cancer

Duke University

NCT02892305

COMPLETED 2,579 participants

Analyses of Human Samples Collected in Clinical Trials

National Cancer Institute (NCI)

NCT00339664

COMPLETED NA 2,512 participants

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

University of Washington

NCT04281784

COMPLETED Phase 3 1,224 participants

Aflibercept in Combination With Docetaxel in Metastatic Androgen Independent Prostate Cancer

Sanofi

NCT00519285

COMPLETED Phase 1 170 participants

A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer

Eli Lilly and Company

NCT01373164

COMPLETED Phase 2 170 participants

Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma

National Cancer Institute (NCI)

NCT00001832

COMPLETED Phase 1 167 participants

A Study of Prexasertib (LY2606368) With Chemotherapy or Targeted Agents in Participants With Advanced Cancer

Eli Lilly and Company

NCT02124148

COMPLETED Phase 4 130 participants

Surgery Versus Radiosurgery to Treat Metastatic Brain Tumors

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00075166

COMPLETED Phase 1 120 participants

An Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastatic Non Small Cell Lung Carcinoma

Eli Lilly and Company

NCT00207116

COMPLETED Phase 1 107 participants

Chemotherapy and Progenitor Cell Transplantation to Treat Inflammatory Breast Cancer

National Cancer Institute (NCI)

NCT00001507

COMPLETED Phase 1 80 participants

A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases

AbbVie (prior sponsor, Abbott)

NCT00649207

COMPLETED Phase 1 80 participants

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

National Cancer Institute (NCI)

NCT00001302

COMPLETED Phase 2 60 participants

Oxaliplatin, Capecitabine and Avastin for Metastatic Esophagogastric Adenocarcinoma

Duke University

NCT00447330

COMPLETED Phase 1 51 participants

Autologous T-Cell Transplantation and the Immunotherapy of Residual Disease in Breast Cancer: Pilot Study of Vaccine-Driven T-Cell Expansion in Patients Treated With Dose-Intensive Chemotherapy

National Cancer Institute (NCI)

NCT00001440

COMPLETED Phase 1 46 participants

A Phase I Study of Continuous Intravenous Infusion of PSC 833 and Vinblastine in Patients With Metastatic Renal Cancer

National Cancer Institute (NCI)

NCT00001570

COMPLETED Phase 2 43 participants

Use of Cetuximab for Unresectable or Metastatic Esophageal and Gastric Cancer

Dana-Farber Cancer Institute

NCT00130689

COMPLETED Phase 2 36 participants

Cetuximab Plus Biweekly Capecitabine and Oxaliplatin in KRAS Wild Type Metastatic Colorectal Cancer

NYU Langone Health

NCT00444678

COMPLETED Phase 2 32 participants

Tarceva and Capecitabine for Pancreatic Cancer

Dana-Farber Cancer Institute

NCT00125021

COMPLETED Phase 1 26 participants

A Study of LY2835219 in Participants With Cancer

Eli Lilly and Company

NCT02117648

COMPLETED 25 participants

Study of Resection Combined With Stereotactic Radiosurgery for 1 to 3 Brain Metastases

University of Rochester

NCT00904553

COMPLETED Phase 1 17 participants

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Stanford University

NCT00946673

COMPLETED Phase 1 9 participants

Study of Safety and Tolerability of Intravenous CRS-100 in Adults With Carcinoma and Liver Metastases

Anza Therapeutics

NCT00327652

COMPLETED Phase 1 8 participants

Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases

University of California, San Diego

NCT01114958

Phase Distribution

PhaseTrial count
Early Phase 1 19
Phase 2 9
Phase 3 8
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neoplasm Metastasis Trial Landscape

ClinicalTrials.gov lists 42 US studies indexed under Neoplasm Metastasis, and 10 of those are currently open to recruitment — roughly 24% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Neoplasm Metastasis shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 28 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Neoplasm Metastasis is led by Eli Lilly and Company with 15 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 42 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neoplasm Metastasis?

PlainTrial tracks 42 US clinical trials for Neoplasm Metastasis, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neoplasm Metastasis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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