Eli Lilly and Company

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Eli Lilly and Company sits in the top decile of US sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count).

1,341 total trials 124 currently recruiting 1029 completed early-phase tilt top decile by trial count

Eli Lilly and Company: 1,341 sponsored US clinical trials, 124 recruiting.

Eli Lilly and Company sponsors 1,341 registered US clinical trials on ClinicalTrials.gov, 124 of them currently recruiting, and 1,029 completed. 459 of these trials are in Phase 3-4 (later-stage) and 861 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 55 trials.

Top-decile sponsor footprint

Eli Lilly and Company ranks in the top decile of sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 67/100

1,029 of 1,131 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,341 total, page 2 of 27

RECRUITING Phase 1

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

NCT07213791

RECRUITING Phase 2

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

NCT07219173

RECRUITING Phase 3

A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

NCT07213804

RECRUITING Phase 3

A Study of Brenipatide in Participants With Alcohol Use Disorder

NCT07219953

RECRUITING Phase 2

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

NCT07215559

RECRUITING Phase 3

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

NCT07165028

RECRUITING Phase 3

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

NCT07219966

RECRUITING Phase 2

A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin

NCT07215312

RECRUITING Phase 3

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

NCT07202884

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

NCT07153471

RECRUITING Phase 3

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

NCT07157774

RECRUITING Phase 1

A Study of LY4064912 in Healthy Participants and With Overweight or Obesity

NCT07152002

RECRUITING Phase 3

Epidemiology and Biomarker Study in Alzheimer's Disease

NCT07142954

RECRUITING NA

A Study Evaluating the Impact of P-tau217 Blood Biomarker Testing on Early Evaluation and Management of Patients Presenting With Cognitive Complaint

NCT07140744

RECRUITING Phase 1

A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function

NCT07137689

RECRUITING Phase 1

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT07114601

RECRUITING Phase 1

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

NCT06721013

RECRUITING Phase 1

A Study of LY4175408 in Participants With Advanced Cancer

NCT07046923

RECRUITING Phase 1

A Study of LY4088044 in Healthy Participants

NCT07090785

RECRUITING Phase 1

A Study of Multiple Olomorasib (LY3537982) Capsules in Healthy Participants

NCT07044271

RECRUITING Phase 3

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

NCT06937099

RECRUITING Phase 3

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

NCT06937086

RECRUITING Phase 4

A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden

NCT07006792

RECRUITING Phase 1

A Study of LY3981314 in Healthy Participants

NCT07005284

RECRUITING Phase 3

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

NCT07035093

RECRUITING Phase 1

A Study of LY3867070 in Healthy Participants

NCT07021547

RECRUITING Phase 4

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

NCT06876662

RECRUITING Phase 4

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

NCT06876649

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes

NCT06972472

RECRUITING Phase 3

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes

NCT06993792

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related Comorbidity

NCT06972459

RECRUITING Phase 1

A Study of LY4268989 (MORF-057) in Healthy Participants

NCT06964776

RECRUITING Phase 3

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1

NCT06948435

RECRUITING Phase 3

A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)

NCT06948422

RECRUITING Phase 3

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2

NCT06952530

RECRUITING Phase 1

A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes

NCT06945419

RECRUITING Phase 1

A Study of Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function

NCT06916078

RECRUITING Phase 1

Comparing the Extent to Which Three Different Formulations of LY4100511 (DC-853) Are Made Available in the Body, Alone and in the Presence of a Drug That Reduces Stomach Acid

NCT06916143

RECRUITING Phase 2

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

NCT06897475

RECRUITING Phase 3

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT06890598

RECRUITING Phase 4

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

NCT06857942

RECRUITING Phase 4

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

NCT06864026

RECRUITING Phase 1

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

NCT06809400

RECRUITING Phase 2

A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder

NCT06817356

RECRUITING Phase 3

A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

NCT06739122

RECRUITING Phase 3

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

NCT06672549

RECRUITING Phase 3

A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

NCT06672939

RECRUITING Phase 1

A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)

NCT06657768

RECRUITING Phase 2

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

NCT06598943

RECRUITING Phase 1

A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus

NCT06362265

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Phase Distribution

PhaseTrial count
Phase 1 517
Phase 2 344
Phase 3 368
Phase 4 91

What is open in the Eli Lilly and Company pipeline

124 recruiting of 1,341 indexed (9% open); 1,029 completed (77%).

Phase mix: 459 late (III/IV) vs 861 early (I/II) (early-phase heavy).

Top condition: Healthy (55 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Eli Lilly and Company: open-pipeline peers nationwide

Peers matched on 1,341 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15% Total trials Recruiting share Eli Lilly and CompanyGlaxoSmithKlineUniversity of MichiganNovartis PharmaceuticalsAstraZenecaShionogiUniversity of KentuckyUniversity of VermontLahey Clinic
Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,341 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this Eli Lilly and Company page

1,341 registered trials is a research-attention snapshot, not an endorsement of Eli Lilly and Company or any single study.

  • 124 of Eli Lilly and Company's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition Eli Lilly and Company studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Eli Lilly and Company pipeline card: 1,341 registered trials from official public datasets.Report a data error.