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NCT06683508 · ClinicalTrials.gov registry record · Phase 2
A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight
A Phase 2 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
- Active
- Registry status
- Phase 2
- Development phase
- 288
- Enrollment target
- 20
- Study locations
NCT06683508: Active Phase 2 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
NCT06683508 is a Phase 2 study of Obesity and Overweight that is active but no longer recruiting, run by Eli Lilly and Company. The registered enrollment target is 288 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (65% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06683508, a Phase 2 study of Obesity and Overweight, is active but no longer recruiting, sponsored by Eli Lilly and Company.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 288 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to evaluate the effects of LY3549492 in adults with obesity or overweight. Participation in the study will last about one year.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG LY3549492
Study Locations (20)
Florida
- Northeast Research Institute (NERI) - Fleming Island
- Indago Research & Health Center, Inc - Hialeah
- New Horizon Research Center - Miami
- Suncoast Clinical Research, Inc. - New Port Richey
- Charter Research - Winter Park - Orlando
- Charter Research - Lady Lake - The Villages
Arizona
- The Institute for Liver Health II dba Arizona Clinical Trials - Mesa - Chandler
- HOPE Research Institute - Phoenix
- Headlands Research - Scottsdale - Scottsdale
- The Institute for Liver Health II dba Arizona Liver Health-Tucson - Tucson
California
- NorCal Medical Research, Inc - Greenbrae
- Velocity Clinical Research, Huntington Park - Huntington Park
- Peninsula Research Associates - Rolling Hills Estates
- Diablo Clinical Research, Inc. - Walnut Creek
Illinois
- Great Lakes Clinical Trials - Andersonville - Chicago
- Great Lakes Clinical Trials - Ravenswood - Chicago
- NorthShore University Health System - Skokie
Connecticut
- Stamford Therapeutics Consortium - Stamford
Idaho
- Medical Research Partners - Ammon
Iowa
- Iowa Diabetes and Endocrinology Research Center - West Des Moines
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 288 participants |
| Start Date | 2024-11-13 |
| Est. Completion | 2026-09 |
| Phase | Phase 2 |
What the registry record for NCT06683508 still lists
NCT06683508 is an interventional study that assigns participants to a tested intervention. The registered 288 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (65% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06683508 names 20 study sites across 7 states, led by Florida, Arizona, California.
Frequently Asked Questions
What is clinical trial NCT06683508 about?
NCT06683508 is a clinical study titled "A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight". The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to evaluate the effects of LY3549492 in adults with obesity or overweight. Participation in the study will last about one year.
What is the current status of trial NCT06683508?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 288 participants. The study started on 2024-11-13. Estimated completion is 2026-09.
What conditions does trial NCT06683508 study?
This clinical trial studies the following conditions: Obesity, Overweight.
What interventions are being tested in trial NCT06683508?
The interventions under investigation include: Placebo (DRUG), LY3549492 (DRUG).
Who is sponsoring clinical trial NCT06683508?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06683508 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06683508's enrollment target sits among peer trials
288 234th of 1053 higher than 819 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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