Total US Trials
60,823 indexed
Medical Disclaimer: PlainTrial provides public information only. Always consult your healthcare provider before enrolling in a clinical trial.
22,403 trials recruiting now · ClinicalTrials.gov
60,823 US clinical trials, in plain language.
The official US trial registry — made searchable, readable, and free.
Search recruiting clinical trials by condition, sponsor, or US state, explore drug-development phase pipelines and rankings, and read plain-language patient guides — every trial record sourced from ClinicalTrials.gov.
60,823
Total Trials
22,403
Recruiting Now
30,015
Conditions
8,714
Sponsors
52
US States & Territories
The national picture
Of 60,823 clinical trials registered across the United States, 22,403 — roughly 37%, or 1 in 3 — are actively recruiting participants right now.
- 22,403
- recruiting now (37% of all registered)
- 30,015
- distinct conditions under study
- 8,714
- sponsors running trials
- 5,207
- in Phase 3 — pivotal efficacy trials
Figures reflect the latest ClinicalTrials.gov snapshot mirrored by PlainTrial. A trial's status and phase are reported by its sponsor to the NIH registry.
Trial Phase Pipeline
Drug-development phases follow a regulatory funnel: early safety testing (Phase 1) through pivotal efficacy trials (Phase 3) to post-marketing surveillance (Phase 4).
Drug Development Phase Distribution
Currently Recruiting
22,403 trials
active enrollment
Phase 2 Pipeline
10,294 trials
largest phase
Conditions Tracked
30,015
Phase 2 share of phase-assigned trials 35.4%
10,294 of 29,092 phase-assigned trials
Recruiting share of all trials 36.8%
22,403 of 60,823 total
Currently Recruiting
View all → Recruiting
Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries
Center for International Blood and Marrow Transplant Research
Target: 99,999,999 participants
NCT04920474
Recruiting
CIBMTR Research Database
Center for International Blood and Marrow Transplant Research
Target: 99,999,999 participants
NCT01166009
Recruiting
IRIS Registry: Intelligent Research in Sight Registry
American Academy of Ophthalmology
Target: 20,000,000 participants
NCT02485847
Recruiting NA
The Effects of Medicaid Policy Interventions on Racial Equity in Severe Maternal Morbidity
University of Pittsburgh
Target: 10,000,000 participants
NCT05678699
Recruiting
National Mammography Database
American College of Radiology
Target: 8,000,000 participants
NCT01900821
Recruiting
The Pediatric Anesthesia Quality Improvement Project
The Society for Pediatric Anesthesia
Target: 5,000,000 participants
NCT00674388
Recruiting
Get With the Guidelines-Stroke Registry
American Heart Association
Target: 3,892,063 participants
NCT02693223
Recruiting
Delivery Room Intervention and Evaluation Network
American Academy of Pediatrics
Target: 3,000,000 participants
NCT06803498
Recruiting
Helix Research Network
Helix
Target: 2,000,000 participants
NCT06057181
Recruiting
Observational Pharmaco-Epidemiology Research & Analysis
Epividian
Target: 2,000,000 participants
NCT03813862
Recruiting
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Massachusetts General Hospital
Target: 1,200,000 participants
NCT07022951
Recruiting
Parkinson's Foundation Surveys
Parkinson's Foundation
Target: 1,000,000 participants
NCT05066763
Most Studied Conditions
All → Breast Cancer
423 recruiting 1,251
Healthy 225 recruiting 1,096
Obesity 306 recruiting 1,057
Prostate Cancer 273 recruiting 747
Depression 245 recruiting 687
Cancer 279 recruiting 621
HIV Infections 56 recruiting 615
Hypertension 152 recruiting 471
Stroke 218 recruiting 456
Multiple Myeloma 167 recruiting 441
Lung Cancer 146 recruiting 430
Heart Failure 164 recruiting 399
Colorectal Cancer 154 recruiting 381
Asthma 70 recruiting 378
Pain 106 recruiting 377
Most Active Sponsors
All → Mayo Clinic 2692 recruiting
3,246 trials M.D. Anderson Cancer Center 2255 recruiting
2,992 trials National Cancer Institute (NCI) 1493 recruiting
2,390 trials Memorial Sloan Kettering Cancer Center 1629 recruiting
2,280 trials Massachusetts General Hospital 1505 recruiting
1,948 trials VA Office of Research and Development 1498 recruiting
1,863 trials Stanford University 1328 recruiting
1,643 trials University of California, San Francis 1220 recruiting
1,574 trials Johns Hopkins University 1232 recruiting
1,517 trials University of Pennsylvania 1100 recruiting
1,457 trials Trial Status Breakdown
Completed
28,000
Recruiting
22,403
Active (not recruiting)
10,420
Find Recruiting Trials
Search by condition and US state to find clinical trials currently recruiting participants near you.
Search recruiting trials →Sponsor Pipelines
Explore what pharmaceutical companies and research institutions are testing. Track pipeline activity by therapeutic area.
Browse sponsors →Phase & Condition Data
Understand where research is concentrated. See phase distribution by condition and track research momentum over time.
View rankings →Frequently Asked Questions
What data does PlainTrial use?
All data comes from ClinicalTrials.gov (National Library of Medicine), the official US registry for publicly funded and privately funded clinical trials. Data is publicly available and updated regularly.
How do I find a recruiting trial for my condition?
Visit the Recruiting Trials page and filter by condition or state. You can also browse the Conditions directory to find active trials for a specific diagnosis.
Is PlainTrial a substitute for medical advice?
No. PlainTrial is an informational resource only. Clinical trial eligibility and enrollment decisions must be made with your healthcare provider. Never enroll in a clinical trial without professional medical guidance.
What do trial phases mean?
Phase 1 tests safety in a small group; Phase 2 evaluates efficacy and side effects; Phase 3 confirms effectiveness in larger populations; Phase 4 monitors approved treatments. Read our guide to clinical trial phases for more detail.
Guides & Analysis
Editorial research and plain-language explainers from our team. Every guide is written to help you read the underlying public data correctly.
Research
Plain-language analysis from our editorial team, built on the public ClinicalTrials.gov registry — see all research.
How to use PlainTrial
Start with your condition, then narrow to what's recruiting near you.
- Search any condition to see every registered trial and its current recruiting status. Browse conditions
- Filter to trials enrolling now, then read each listing for eligibility and study locations. Recruiting trials
- Learn what a trial phase actually means before you judge a listing. Phase guide
- Check which sponsors and US states run the most trials in your area of interest. View rankings
PlainTrial mirrors public ClinicalTrials.gov records for reference only and is not medical advice. Eligibility and enrollment decisions must be made with a licensed healthcare provider.