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NCT06662383 · ClinicalTrials.gov registry record · Phase 3
A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
A Phase 3 study of Obesity, sponsored by Eli Lilly and Company.
- Active
- Registry status
- Phase 3
- Development phase
- 800
- Enrollment target
- 20
- Study locations
NCT06662383: Active Phase 3 study of Obesity, sponsored by Eli Lilly and Company.
NCT06662383 is a Phase 3 study of Obesity that is active but no longer recruiting, run by Eli Lilly and Company. The registered enrollment target is 800 participants, roughly in line with the 818-participant average among 1,053 other Obesity trials with a reported enrollment target. The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06662383, a Phase 3 study of Obesity, is active but no longer recruiting, sponsored by Eli Lilly and Company.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 800 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main purpose of this study is to evaluate the efficacy and safety of retatrutide compared to tirzepatide in adults who have obesity. The study will last about 89 weeks.
Conditions Studied
Interventions
- DRUG Tirzepatide
- DRUG Retatrutide
Study Locations (20)
Florida
- Encore Medical Research - Hollywood
- Suncoast Research Group - Miami
- Onhealth Research Center - Miami
- Precision Clinical Research - Sunrise
- Einstein Clinical Research - Vero Beach
California
- Mary & Dick Allen Diabetes Center - Newport Beach
- Artemis Institute for Clinical Research - San Diego
- Encompass Clinical Research - Spring Valley
- Diablo Clinical Research, Inc. - Walnut Creek
Georgia
- ClinCept Clinical Research - MH - Columbus
- Northeast Georgia Medical Center - Gainesville
- Pivotal Research Solutions - Stonecrest
Connecticut
- Bridgeport Hospital - Bridgeport
- Yale University School of Medicine - New Haven
Arizona
- Medical Advancement Centers of Arizona - Tempe
Colorado
- Lynn Institute of Denver - Aurora
Hawaii
- East-West Medical Research Institute - Honolulu
Illinois
- Northwestern University - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2024-11-01 |
| Est. Completion | 2026-12 |
| Phase | Phase 3 |
What the registry record for NCT06662383 still lists
NCT06662383 is an interventional study that assigns participants to a tested intervention. The registered 800 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 818-participant average among 1,053 other Obesity trials with a reported enrollment target.
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Tirzepatide is the first listed.
NCT06662383 names 20 study sites across 10 states, led by Florida, California, Georgia.
Frequently Asked Questions
What is clinical trial NCT06662383 about?
NCT06662383 is a clinical study titled "A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity". The main purpose of this study is to evaluate the efficacy and safety of retatrutide compared to tirzepatide in adults who have obesity. The study will last about 89 weeks.
What is the current status of trial NCT06662383?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 800 participants. The study started on 2024-11-01. Estimated completion is 2026-12.
What conditions does trial NCT06662383 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT06662383?
The interventions under investigation include: Tirzepatide (DRUG), Retatrutide (DRUG).
Who is sponsoring clinical trial NCT06662383?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06662383 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06662383's enrollment target sits among peer trials
800 91st of 1053 higher than 962 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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