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Diabetes Mellitus, Type 2: full-pipeline trial registry
63 of 351 indexed Diabetes Mellitus, Type 2 trials are currently recruiting.
Corpus placement: #18 of 28,707 conditions by registered trial count.
351 US clinical trials · 63 currently recruiting · #18 of 28,707 conditions by registered trial count
Diabetes Mellitus, Type 2: 351 US clinical trials tracked, 63 recruiting.
Diabetes Mellitus, Type 2 is the subject of 351 registered US clinical trials on ClinicalTrials.gov, 63 of them currently open to new participants. 100 are in Phase 3-4 (later-stage) and 80 in Phase 1-2 (earlier-stage). The most active sponsor is Novo Nordisk A/S, running 48 of these trials.
Enrollment posture brief
Registry condition diabetes-mellitus-type-2
OPEN 63 | RECR 18% | LATE 100 | EARLY 80 | RANK #18 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Acute Myelogenous Leukemia (18% recruiting · 39 trials)
Diabetes Mellitus, Type 2 lists 63 open slots (18% of 351 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diabetes Mellitus, Type 2 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diabetes Mellitus, Type 2 is recruiting below its size-band peers.
63 of 351 indexed trials (17.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diabetes Mellitus, Type 2 trials is spread across many organizations.
Novo Nordisk A/S accounts for 48 of 351 trials (13.7%). 143 distinct sponsors appear on at least one study for this condition label.
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Typical Diabetes Mellitus, Type 2 enrolment sits around 150 participants.
Median target enrolment is 150 among the 349 trials that report a genuine target (sentinel values excluded). 142 of those (40.7%) plan for fewer than 100 participants.
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Diabetes Mellitus, Type 2 research is mostly interventional.
321 interventional and 30 observational studies make up this index (91.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
351 total, page 1 of 8
Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)
Stanford University
NCT06251323
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Boehringer Ingelheim
NCT07064473
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly
NCT06112418
Blood Markers of Early Pancreas Cancer
University of Nebraska
NCT03568630
Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships
Boston Medical Center
NCT07043426
Promoting Preconception Care and Diabetes Self-Management Among Reproductive-Aged Women With Diabetes
Northwestern University
NCT04976881
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
The University of Texas Health Science Center at San Antonio
NCT02969798
Linking Education, Produce Provision, and Community Referrals to Improve Diabetes Care (LINK)
Ohio State University
NCT05472441
Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
University of South Carolina
NCT05370014
Healthy Communities Through CHW Initiatives
The University of Texas Medical Branch, Galveston
NCT05965869
Safer Aging With Diabetes Monitoring
Kaiser Permanente
NCT06296485
DETERMINE: Detemir vs NPH
University of California, Los Angeles
NCT05124457
Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus
Medical College of Wisconsin
NCT05692388
Increasing CGM Use Among Patients With T2D
San Diego State University
NCT06638099
Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk
Kaiser Permanente
NCT06067139
Effect of Continuing Versus Holding Metformin During Hospitalizations.
University of Illinois at Chicago
NCT06296836
Family Model DSME in FBOs in the RMI
University of Arkansas
NCT05502016
Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes
Massachusetts General Hospital
NCT05420051
Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes
Endogenex
NCT06267391
Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
University of Colorado, Denver
NCT07011147
Care Navigator Support for Younger Latinx Adults With Type 2 Diabetes
Kaiser Permanente
NCT05754008
Food as Medicine for HIV and Diabetes
University of North Carolina, Chapel Hill
NCT05026723
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
Eli Lilly and Company
NCT07215559
Transformative Research in Diabetic Nephropathy 2.0
University of Pennsylvania
NCT07444203
PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
Aventusoft
NCT06567795
Food Insecurity Reduction & Strategy Team
Stanford University
NCT06329375
Drug Interaction Potential of Pro-Inflammatory Conditions
Indiana University
NCT07360938
Strategies to Improve Well-Being and Diabetes Management
Elizabeth Scharnetzki
NCT06348238
Diabetes Learning in Virtual Environments Just in Time for Community Reentry
Louise Reagan
NCT05286892
Diabetes Toolkit at Discharge
Northwestern University
NCT05663931
Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes
University of Kansas Medical Center
NCT06478186
HOPE Intervention for Fitness
University of California, Irvine
NCT07114822
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
Stanford University
NCT05165706
Phenotyping Genetic Risk for Type 2 Diabetes
University of Pennsylvania
NCT04024631
MANAGe-DM: Novel Nurse Case Management to Improve Diabetes Outcomes in Formerly Incarcerated Black Men
Medical College of Wisconsin
NCT06031428
Post Prandial Individual Responses to Different Foods
Stanford University
NCT06989164
A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin
Eli Lilly and Company
NCT07215312
Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes
Seattle Children's Hospital
NCT06936670
Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature
Senseonics
NCT07386340
Michigan Men's Diabetes Project III(MenDIII): Mind and Motion
University of Michigan
NCT06574035
Use of CGM in Kidney Transplant Recipients
University of California, Davis
NCT04783441
OASIS: Peer Support for T2DM in Appalachia (Peer Participant)
University of Kentucky
NCT06336122
Promoting Intergenerational Health in Rural Kentuckians With Diabetes (PIHRK'D)
The University of Texas Medical Branch, Galveston
NCT06080425
Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes
The Reading Hospital and Medical Center
NCT05893927
Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)
Merck Sharp & Dohme
NCT07089784
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)
Bettina Mittendorfer
NCT06571474
Time-Restricted Eating for Type II Diabetes: TRE-T2D
University of California, San Diego
NCT05365529
In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes
Cornell University
NCT06557317
A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006)
Merck Sharp & Dohme
NCT07242469
Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes
Samita Garg
NCT06046833
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 42 |
| Phase 2 | 38 |
| Phase 3 | 74 |
| Phase 4 | 26 |
Top Sponsors
Named interventions
Most-linked intervention names on Diabetes Mellitus, Type 2 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diabetes Mellitus, Type 2 trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diabetes Mellitus, Type 2 page
351 registered trials, 63 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 63 Diabetes Mellitus, Type 2 trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Novo Nordisk A/S sponsors the most Diabetes Mellitus, Type 2 trials on record, review their full trial history before evaluating a specific study. See Novo Nordisk A/S's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Mellitus, Type 2 condition card totals 351 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.