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NCT05784246 · ClinicalTrials.gov registry record · Phase 3
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis
A Phase 3 study of Ulcerative Colitis, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 60
- Enrollment target
- 20
- Study locations
NCT05784246: Recruiting Phase 3 study of Ulcerative Colitis, sponsored by Eli Lilly and Company.
NCT05784246 is a Phase 3 study of Ulcerative Colitis that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 60 participants, below the 2,057-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (97% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05784246, a Phase 3 study of Ulcerative Colitis, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 60 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main purpose of this study is to investigate efficacy, pharmacokinetics and safety of the drug in pediatric participants with moderately to severely active ulcerative colitis (UC).
Conditions Studied
Interventions
- DRUG Mirikizumab IV
- DRUG Mirikizumab SC
Study Locations (20)
Other
- UZA - Edegem
- UZ Leuven - Leuven
- The Hospital for Sick Children - Toronto
- Hôpital Necker - Enfants Malades - Paris
- Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz - Mainz
- LMU-Campus Innenstadt - München
- Helios Klinikum Wuppertal - Wuppertal
- Shaare Zedek - Jerusalem
- Hadassah University Hospital, Ein Kerem - Jerusalem
- Schneider Children's Medical Center - Petah Tikva
- King Fahad Medical City - Rishon LeZiyyon
- Azienda Ospedaliero Universitaria Ospedale Pediatrico Meyer - Florence
- Azienda Ospedaliera Universitaria Policlinico Umberto I - Università di Roma La Sapienza - Roma
- Juntendo University Hospital - Bunkyō City
California
- University of California, San Francisco - San Francisco
Georgia
- Children's Center for Digestive Health Care, LLC - Atlanta
Indiana
- Riley Childrens Hospital - Indianapolis
Missouri
- Washington University - St Louis
New York
- Icahn School of Medicine at Mount Sinai - New York
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-11-22 |
| Est. Completion | 2026-08 |
| Phase | Phase 3 |
What NCT05784246 shows while recruiting
NCT05784246 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 2,057-participant average among 122 other Ulcerative Colitis trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Ulcerative Colitis appearing as the primary indexed condition, and to 2 interventions - of which Mirikizumab IV is the first listed.
NCT05784246 names 20 study sites across 7 states, led by Other, California, Georgia.
Frequently Asked Questions
What is clinical trial NCT05784246 about?
NCT05784246 is a clinical study titled "A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis". The main purpose of this study is to investigate efficacy, pharmacokinetics and safety of the drug in pediatric participants with moderately to severely active ulcerative colitis (UC).
What is the current status of trial NCT05784246?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 60 participants. The study started on 2023-11-22. Estimated completion is 2026-08.
What conditions does trial NCT05784246 study?
This clinical trial studies the following conditions: Ulcerative Colitis.
What interventions are being tested in trial NCT05784246?
The interventions under investigation include: Mirikizumab IV (DRUG), Mirikizumab SC (DRUG).
Who is sponsoring clinical trial NCT05784246?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05784246 being conducted?
This trial has 20 study locations across California, Georgia, Indiana, Missouri, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ulcerative Colitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05784246's enrollment target sits among peer trials
60 79th of 122 higher than 43 of 122 other Ulcerative Colitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ulcerative Colitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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