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A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)
NCT06339008 · View on ClinicalTrials.gov ↗
Study Summary
The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in adult participants with perennial allergic rhinitis. Participants can expect study participation to last up to 29.5 months.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG LY3650150
- DRUG Standard therapy for INCS
Study Locations (20)
California
- Allergy and Asthma Specialists Medical Group — Huntington Beach
- 310 Clinical Research — Inglewood
- Allergy & Asthma Associates of Southern California dba. Southern California Research — Laguna Niguel
- Allergy and Asthma — San Diego
New Jersey
- Circuit Clinical/Hudson-Essex Allergy — Belleville
- Circuit Clinical/Mercer Allergy and Pulmonary Associates — Hamilton
- Dr. Patrick Perin — Teaneck
Florida
- Allergy and Asthma Diagnostic Center — Tallahassee
- University of South Florida — Tampa
Illinois
- Northwestern University — Chicago
- Asthma Allergy Center of Chicago — River Forest
Missouri
- University of Missouri Hospital — Columbia
- Allergy and Asthma Consultants — St Louis
Colorado
- Asthma and Allergy Associates, PC — Colorado Springs
Kentucky
- Bluegrass Allergy Research — Lexington
Michigan
- Respiratory Medicine Research Institute of Michigan, PLC — Ypsilanti
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 450 participants |
| Start Date | 2024-04-26 |
| Est. Completion | 2028-10 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06339008
The ClinicalTrials.gov registry entry for NCT06339008 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 450 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Perennial Allergic Rhinitis (PAR) appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06339008 reports 20 study locations spanning 12 distinct geographic areas — top geographies include California, New Jersey, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06339008 about?
NCT06339008 is a clinical study titled "A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)". The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in adult participants with perennial allergic rhinitis. Participants can expect study participation to last up to 29.5 months.
What is the current status of trial NCT06339008?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 450 participants. The study started on 2024-04-26. Estimated completion is 2028-10.
What conditions does trial NCT06339008 study?
This clinical trial studies the following conditions: Perennial Allergic Rhinitis (PAR). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06339008?
The interventions under investigation include: Placebo (DRUG), LY3650150 (DRUG), Standard therapy for INCS (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06339008?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06339008 being conducted?
This trial has 20 study locations across California, Colorado, Florida, Illinois, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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