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NCT06400472 · ClinicalTrials.gov registry record · Phase 1
A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
A Phase 1 study of Carcinoma, Non-Small Cell Lung and Colorectal Neoplasms, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 495
- Enrollment target
- 20
- Study locations
NCT06400472 is a Phase 1 study of Carcinoma, Non-Small Cell Lung and Colorectal Neoplasms that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 495 participants, above the 320-participant average among 130 other Carcinoma, Non-Small Cell Lung trials with a reported enrollment target (55% higher). The trial reports 20 study locations across 8 states.
The verdict
NCT06400472, a Phase 1 study of Carcinoma, Non-Small Cell Lung and Colorectal Neoplasms, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 495 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to find out whether the study drug, LY4170156, is safe, tolerable and effective in participants with advanced solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approximately 4 years.
Conditions Studied
Interventions
- DRUG pembrolizumab
- DRUG Itraconazole
- DRUG carboplatin
- DRUG bevacizumab
- DRUG LY4170156
Study Locations (20)
Other
- Cancer Research SA - Adelaide
- Icon Cancer Centre South Brisbane - QLD
- Centre Leon Berard - Lyon
- Institut de Cancerologie de l'Ouest - site St-Herblain - Saint-Herblain
- Oncopole Claudius Regaud - Toulouse
- Istituto Europeo di Oncologia - Milan
- Istituto Clinico Humanitas - Rozzano
- Shizuoka Cancer Center - Shizuoka
- National Cancer Center Hospital - Tokyo
- Cancer Institute Hospital of JFCR - Tokyo
- National Cancer Center - Goyang-si Gyeonggi-do
New York
- NYU Langone Health - Long Island - Mineola
- New York University (NYU) Clinical Cancer Center - New York
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center - New York
Arizona
- HonorHealth - Scottsdale
California
- University of California, San Diego (UCSD) - Moores Cancer Center - La Jolla
Michigan
- South Texas Accelerated Research Therapeutics (START) Midwest - Grand Rapids
Ohio
- The Ohio State University (OSU) Wexner Medical Center - Columbus
Texas
- The University of Texas - MD Anderson Cancer Center - Houston
Utah
- START Mountain Region - West Valley City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 495 participants |
| Start Date | 2024-05-20 |
| Est. Completion | 2027-04 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06400472
The ClinicalTrials.gov registry entry for NCT06400472 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 495 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 320-participant average among 130 other Carcinoma, Non-Small Cell Lung trials with a reported enrollment target (55% higher). The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.
The record links to 7 conditions, with Carcinoma, Non-Small Cell Lung appearing as the primary indexed condition, and to 5 interventions - of which pembrolizumab is the first listed.
NCT06400472 reports 20 study locations spanning 8 distinct geographic areas - top geographies include Other, New York, Arizona.
Frequently Asked Questions
What is clinical trial NCT06400472 about?
NCT06400472 is a clinical study titled "A Study of LY4170156 in Participants With Selected Advanced Solid Tumors". The purpose of this study is to find out whether the study drug, LY4170156, is safe, tolerable and effective in participants with advanced solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approx...
What is the current status of trial NCT06400472?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 495 participants. The study started on 2024-05-20. Estimated completion is 2027-04.
What conditions does trial NCT06400472 study?
This clinical trial studies the following conditions: Carcinoma, Non-Small Cell Lung, Colorectal Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms, Pancreatic Neoplasm.
What interventions are being tested in trial NCT06400472?
The interventions under investigation include: pembrolizumab (DRUG), Itraconazole (DRUG), carboplatin (DRUG), bevacizumab (DRUG), LY4170156 (DRUG).
Who is sponsoring clinical trial NCT06400472?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06400472 being conducted?
This trial has 20 study locations across Arizona, California, Michigan, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.