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ClinicalTrials.gov 126 recruiting now official registry

Aging clinical trials

126 of 263 indexed Aging trials are currently recruiting.

263 US clinical trials · 126 currently recruiting

Aging is the subject of 263 registered US clinical trials on ClinicalTrials.gov, 126 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 48 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 14 of these trials.

The research picture

Aging has 263 registered US clinical trials, 126 of them open to new participants right now, about 48% of the total.

126
recruiting participants now
48%
of trials open to enrollment
14
in Phase 3–4 (later-stage)
14
top sponsor: University of Florida
Phase 129Phase 219Phase 36Phase 48

Active & Recent Trials

263 total, page 3 of 6

RECRUITING NA 32 participants

Far Red Light to Improve Functioning in PAD

Northwestern University

NCT06165016

RECRUITING NA 32 participants

ENhancing Exercise with LIGHT to Improve Functioning in PAD

Northwestern University

NCT06399900

RECRUITING Phase 4 32 participants

Skin Barrier Function and Inflammation in Aging: The BIA Study

University of California, San Francisco

NCT06750653

RECRUITING NA 30 participants

Ketone Ester And Salt (KEAS) in Older Adults

Indiana University

NCT06868719

RECRUITING 30 participants

Glucose Variability and Cognition in Prediabetes

University of Maryland, Baltimore

NCT04201600

RECRUITING Early Phase 1 30 participants

Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems

Weinberg Medical Physics

NCT06779188

RECRUITING NA 30 participants

Spinal Networks of Balance Learning and Retention in Older Adults

University of Florida

NCT06517043

RECRUITING Phase 2 30 participants

Fiber and Calcium Absorption in Older Men

VA Office of Research and Development

NCT06519877

RECRUITING NA 30 participants

Walking Sensation Study

University of Florida

NCT06975423

RECRUITING Early Phase 1 26 participants

Angiotensin-(1-7) Cardiovascular Effects in Aging

Milton S. Hershey Medical Center

NCT05301192

RECRUITING NA 24 participants

Pilot Intervention With Near Infrared Stimulation

University of Florida

NCT03551392

RECRUITING Early Phase 1 24 participants

Gene Expression Changes In Young and Geriatric Skin

Wright State University

NCT03932162

RECRUITING NA 24 participants

Adipose Tissue Blood Flow in Aging Humans

Mayo Clinic

NCT06096532

RECRUITING Phase 4 24 participants

Role of Menopause in Thermoregulation

Penn State University

NCT06798571

RECRUITING NA 24 participants

C-Protein in Fatigue and Aging

University of Oregon

NCT05926219

RECRUITING 24 participants

Impact of Extreme Heat on Myocardial Blood Flow and Flow Reserve in Young and Older Adults

University of Texas Southwestern Medical Center

NCT06842784

RECRUITING Phase 4 22 participants

Aging, Beta Blockers, and Thermoregulatory Responses

University of Texas Southwestern Medical Center

NCT06582680

RECRUITING NA 20 participants

The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers

University of Miami

NCT07415707

RECRUITING Early Phase 1 20 participants

Heat, Microvascular Function and Aging

William Hughes

NCT06633198

RECRUITING NA 20 participants

Western Diet on Cardiometabolic and Immune Function

University of Delaware

NCT06528977

RECRUITING NA 20 participants

Ultrasound for Healthy Aging

The University of Texas Health Science Center at San Antonio

NCT07168525

RECRUITING Phase 2 20 participants

Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study

Washington University School of Medicine

NCT07000734

RECRUITING NA 16 participants

Cognitive Vitality Pilot Study

Arizona State University

NCT07208279

RECRUITING NA 15 participants

Dehydration, Rehydration, and Impact on Physiology

Texas Tech University

NCT07084675

RECRUITING NA 12 participants

Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults

University of Missouri-Columbia

NCT06689618

RECRUITING Phase 2 10 participants

The Role of Sirolimus in Preventing Functional Decline in Older Adults

Irina Timofte

NCT05237687

ACTIVE NOT RECRUITING 1,000 participants

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

Ohio State University

NCT06357195

ACTIVE NOT RECRUITING NA 650 participants

Impact of a Novel Brain Longevity Supplement Containing the Postbiotic Urolithin A (Mitopure) on Cognitive Function and Related Health Outcomes

Amazentis

NCT07060898

ACTIVE NOT RECRUITING Phase 3 629 participants

ACHIEVE Brain Health Follow-Up Study

Johns Hopkins University

NCT05532657

ACTIVE NOT RECRUITING NA 600 participants

Prepare for Your Diabetes Care

Kaiser Permanente

NCT05263310

ACTIVE NOT RECRUITING NA 479 participants

Improving Communication for Cancer Treatment: Addressing Concerns of Older Cancer Patients and Caregivers

M.D. Anderson Cancer Center

NCT05436327

ACTIVE NOT RECRUITING NA 400 participants

Underutilization of Hospice Care in Older Black Adults

University of Colorado, Denver

NCT06408090

ACTIVE NOT RECRUITING 340 participants

Couples Health Aging, Rhythms and Sleep Study

University of Utah

NCT05952284

ACTIVE NOT RECRUITING NA 300 participants

A Social Media Game to Increase Physical Activity Among Older Adult Women

The University of Texas Medical Branch, Galveston

NCT04095923

ACTIVE NOT RECRUITING NA 238 participants

Music Improvisation Training on Cognitive Function in Older Adults

University of California, San Francisco

NCT06721390

ACTIVE NOT RECRUITING 194 participants

Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia

University of Texas Southwestern Medical Center

NCT04951700

ACTIVE NOT RECRUITING NA 184 participants

Feasibility of the Comfort Measures Only Time Out (CMOT)

Beth Israel Deaconess Medical Center

NCT05861323

ACTIVE NOT RECRUITING 130 participants

Passive Limb Movement: A Tool to Assess Vascular Health and Guide Rehabilitation

VA Office of Research and Development

NCT03625349

ACTIVE NOT RECRUITING NA 126 participants

The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance

Massachusetts General Hospital

NCT04908358

ACTIVE NOT RECRUITING Phase 2 112 participants

Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans

University of Colorado, Boulder

NCT04851288

ACTIVE NOT RECRUITING Phase 2 106 participants

Everolimus Aging Study

University of Wisconsin, Madison

NCT05835999

ACTIVE NOT RECRUITING NA 90 participants

Accelerating Cognitive Gains From Digital Inverventions With Noninvasive Brain Stimulation

University of California, San Francisco

NCT06633952

ACTIVE NOT RECRUITING NA 90 participants

DiAL Health Research Study

Pennington Biomedical Research Center

NCT05549362

ACTIVE NOT RECRUITING Phase 1 70 participants

Fisetin to Improve Vascular Function in Older Adults

University of Colorado, Boulder

NCT06133634

ACTIVE NOT RECRUITING Phase 1 58 participants

Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women

Colorado State University

NCT04530916

ACTIVE NOT RECRUITING Phase 4 55 participants

Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics (NoMEN Study)

University of Colorado, Denver

NCT05057546

ACTIVE NOT RECRUITING Early Phase 1 52 participants

A Pilot Study on Reverse Aging (The REVERSE Study)

The Christ Hospital

NCT07354620

ACTIVE NOT RECRUITING 50 participants

Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments

University of Wisconsin, Madison

NCT06184919

ACTIVE NOT RECRUITING Phase 3 40 participants

The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics

Dobri Kiprov

NCT06534450

ACTIVE NOT RECRUITING NA 40 participants

Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors

University of Washington

NCT05467410

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Phase Distribution

PhaseTrial count
Phase 1 29
Phase 2 19
Phase 3 6
Phase 4 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Aging Trial Landscape

263 indexed Aging studies · 126 recruiting (48%).

Phase mix: 14 late (III/IV) vs 48 early (I/II).

Top sponsor: University of Florida (14 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Aging?

PlainTrial tracks 263 US clinical trials for Aging, of which 126 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Aging?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.