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Aging clinical trials
126 of 263 indexed Aging trials are currently recruiting.
263 US clinical trials · 126 currently recruiting
Aging is the subject of 263 registered US clinical trials on ClinicalTrials.gov, 126 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 48 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 14 of these trials.
The research picture
Aging has 263 registered US clinical trials, 126 of them open to new participants right now, about 48% of the total.
- 126
- recruiting participants now
- 48%
- of trials open to enrollment
- 14
- in Phase 3–4 (later-stage)
- 14
- top sponsor: University of Florida
Active & Recent Trials
263 total, page 3 of 6
Far Red Light to Improve Functioning in PAD
Northwestern University
NCT06165016
ENhancing Exercise with LIGHT to Improve Functioning in PAD
Northwestern University
NCT06399900
Skin Barrier Function and Inflammation in Aging: The BIA Study
University of California, San Francisco
NCT06750653
Ketone Ester And Salt (KEAS) in Older Adults
Indiana University
NCT06868719
Glucose Variability and Cognition in Prediabetes
University of Maryland, Baltimore
NCT04201600
Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems
Weinberg Medical Physics
NCT06779188
Spinal Networks of Balance Learning and Retention in Older Adults
University of Florida
NCT06517043
Fiber and Calcium Absorption in Older Men
VA Office of Research and Development
NCT06519877
Walking Sensation Study
University of Florida
NCT06975423
Angiotensin-(1-7) Cardiovascular Effects in Aging
Milton S. Hershey Medical Center
NCT05301192
Pilot Intervention With Near Infrared Stimulation
University of Florida
NCT03551392
Gene Expression Changes In Young and Geriatric Skin
Wright State University
NCT03932162
Adipose Tissue Blood Flow in Aging Humans
Mayo Clinic
NCT06096532
Role of Menopause in Thermoregulation
Penn State University
NCT06798571
C-Protein in Fatigue and Aging
University of Oregon
NCT05926219
Impact of Extreme Heat on Myocardial Blood Flow and Flow Reserve in Young and Older Adults
University of Texas Southwestern Medical Center
NCT06842784
Aging, Beta Blockers, and Thermoregulatory Responses
University of Texas Southwestern Medical Center
NCT06582680
The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers
University of Miami
NCT07415707
Heat, Microvascular Function and Aging
William Hughes
NCT06633198
Western Diet on Cardiometabolic and Immune Function
University of Delaware
NCT06528977
Ultrasound for Healthy Aging
The University of Texas Health Science Center at San Antonio
NCT07168525
Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot Study
Washington University School of Medicine
NCT07000734
Cognitive Vitality Pilot Study
Arizona State University
NCT07208279
Dehydration, Rehydration, and Impact on Physiology
Texas Tech University
NCT07084675
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
University of Missouri-Columbia
NCT06689618
The Role of Sirolimus in Preventing Functional Decline in Older Adults
Irina Timofte
NCT05237687
DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients
Ohio State University
NCT06357195
Impact of a Novel Brain Longevity Supplement Containing the Postbiotic Urolithin A (Mitopure) on Cognitive Function and Related Health Outcomes
Amazentis
NCT07060898
ACHIEVE Brain Health Follow-Up Study
Johns Hopkins University
NCT05532657
Prepare for Your Diabetes Care
Kaiser Permanente
NCT05263310
Improving Communication for Cancer Treatment: Addressing Concerns of Older Cancer Patients and Caregivers
M.D. Anderson Cancer Center
NCT05436327
Underutilization of Hospice Care in Older Black Adults
University of Colorado, Denver
NCT06408090
Couples Health Aging, Rhythms and Sleep Study
University of Utah
NCT05952284
A Social Media Game to Increase Physical Activity Among Older Adult Women
The University of Texas Medical Branch, Galveston
NCT04095923
Music Improvisation Training on Cognitive Function in Older Adults
University of California, San Francisco
NCT06721390
Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia
University of Texas Southwestern Medical Center
NCT04951700
Feasibility of the Comfort Measures Only Time Out (CMOT)
Beth Israel Deaconess Medical Center
NCT05861323
Passive Limb Movement: A Tool to Assess Vascular Health and Guide Rehabilitation
VA Office of Research and Development
NCT03625349
The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance
Massachusetts General Hospital
NCT04908358
Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans
University of Colorado, Boulder
NCT04851288
Everolimus Aging Study
University of Wisconsin, Madison
NCT05835999
Accelerating Cognitive Gains From Digital Inverventions With Noninvasive Brain Stimulation
University of California, San Francisco
NCT06633952
DiAL Health Research Study
Pennington Biomedical Research Center
NCT05549362
Fisetin to Improve Vascular Function in Older Adults
University of Colorado, Boulder
NCT06133634
Wild Blueberries and Cardiovascular Health in Middle-aged/Older Men and Postmenopausal Women
Colorado State University
NCT04530916
Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics (NoMEN Study)
University of Colorado, Denver
NCT05057546
A Pilot Study on Reverse Aging (The REVERSE Study)
The Christ Hospital
NCT07354620
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
University of Wisconsin, Madison
NCT06184919
The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics
Dobri Kiprov
NCT06534450
Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors
University of Washington
NCT05467410
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 29 |
| Phase 2 | 19 |
| Phase 3 | 6 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Aging Trial Landscape
263 indexed Aging studies · 126 recruiting (48%).
Phase mix: 14 late (III/IV) vs 48 early (I/II).
Top sponsor: University of Florida (14 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Aging?
PlainTrial tracks 263 US clinical trials for Aging, of which 126 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Aging?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.