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Aging: early-phase trial registry
126 of 263 indexed Aging trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #38 of 28,707 conditions by registered trial count.
263 US clinical trials · 126 currently recruiting · #38 of 28,707 conditions by registered trial count
Aging: 263 US clinical trials tracked, 126 recruiting.
Aging is the subject of 263 registered US clinical trials on ClinicalTrials.gov, 126 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 48 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 14 of these trials.
Enrollment posture brief
Registry condition aging
OPEN 126 | RECR 48% | LATE 14 | EARLY 48 | RANK #38 | SPON 14
Volume-matched condition peers
Nearest open-share peer: Lung Non-Small Cell Carcinoma (48% recruiting · 48 trials)
Aging lists 126 open slots (48% of 263 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Aging on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Aging is recruiting above its size-band peers.
126 of 263 indexed trials (47.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Aging trials is spread across many organizations.
University of Florida accounts for 14 of 263 trials (5.3%). 132 distinct sponsors appear on at least one study for this condition label.
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Most Aging trials plan to enrol fewer than 100 people.
Median target enrolment is 66 among the 263 trials that report a genuine target (sentinel values excluded). 166 of those (63.1%) plan for fewer than 100 participants.
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Aging research is mostly interventional.
228 interventional and 35 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
263 total, page 4 of 6
Aerobic Exercise and Cerebrovascular Function
VA Office of Research and Development
NCT03803904
Effects of MetAP2 Inhibition on Bioenergetics and Aging-associated Characteristics in Adipose Tissue in Healthy Participants
AdventHealth Translational Research Institute
NCT05989035
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure
University of Pittsburgh
NCT06576297
Combination Gerotherapeutic Interventions for Healthspan Improvement
AgelessRx
NCT07475546
Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness
University of Maryland, Baltimore
NCT05968144
Personalized Approach to Promote Healthy Aging
Arizona State University
NCT06734468
Brown Adipose Tissue Pilot
AdventHealth Translational Research Institute
NCT03793127
Restylane Refyne for Correction of Horizontal Neck Rhytides
Siperstein Dermatology
NCT04162496
MitoQ and Exercise Effects on Vascular Health
University of Colorado, Denver
NCT05686967
Digital Literacy Intervention to Address Support, Literacy and Communication in Older Adults
Johns Hopkins University
NCT06479707
RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)
Teoxane
NCT06378086
Greens-Based Crossover Trial to Improve Epigenetic Aging in Adults
Auburn University
NCT06537232
The Fuel and Rhythm (FAR) Phase 2 Study
University of Florida
NCT05482711
Individualized Brain Stimulation to Improve Mobility in Alzheimer's Disease
Hebrew SeniorLife
NCT04289402
Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults
University of Florida
NCT04276805
Isa-Pom-Dex in Elderly/Frail Subjects With RRMM
UNC Lineberger Comprehensive Cancer Center
NCT05911321
Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19
Mayo Clinic
NCT04551339
Trial of the Impact of the Electronic Frailty Integrated With Social Needs
Wake Forest University Health Sciences
NCT05293730
MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care
VA Office of Research and Development
NCT00400062
Health Outcomes After Participating in Exercise (HOPE)
Wake Forest University Health Sciences
NCT03430115
Functionally Validated Structural Endpoints for Early AMD
Cynthia Owsley
NCT04112667
Improvement in Memory With Plasticity-Based Adaptive Cognitive Training (IMPACT)
Posit Science Corporation
NCT00283010
Preparing Older Veterans With Serious and Chronic Illness for Decision Making
VA Office of Research and Development
NCT01550731
Life 2: Improving Fitness and Function in Elders
US Department of Veterans Affairs
NCT00435188
ABC Trial: Awakening and Breathing Controlled
National Institute on Aging (NIA)
NCT00097630
MY PALS: A Community-Based Physical Activity Support Program for Older Adults
University of Washington
NCT00132288
SeniorWISE: Improving Everyday Memory in At-Risk Elderly
National Institute on Aging (NIA)
NCT00094731
CALERIE: Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
Duke University
NCT00427193
Optimizing Electronic Health Record Prompts With Behavioral Economics to Improve Prescribing for Older Adults
Brigham and Women's Hospital
NCT04284553
Internet-based Conversational Engagement Clinical Trial
Massachusetts General Hospital
NCT02871921
Activities for Cognitive Enhancement of Seniors
Stanford University
NCT01094509
Immune Response to Pneumococcal Vaccination in Aging HIV Positive Adults
Medical University of South Carolina
NCT03039491
A Needs-focused Palliative Care Intervention for Older Adults in ICUs
Duke University
NCT04414787
Mindfulness Meditation in Chronic Stress
Oregon Health and Science University
NCT01386060
Stretching and Yoga Exercise Study
University of Illinois at Urbana-Champaign
NCT01650532
Oxytocin's Effect on Socioemotional Aging
University of Florida
NCT01823146
Frequency of Aerobic/Resistance Training in Older Women
University of Alabama at Birmingham
NCT01031394
Effect of Exercise Intervention on Various Physiologic Factors That Change With Increasing Age
Mayo Clinic
NCT00283673
Health in Motion- A Pragmatic Clinical Trial- Home
Blue Marble Rehab
NCT05016141
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
University of Colorado, Denver
NCT02042196
Exercise, Executive Processes and the Aging Brain
National Institute on Aging (NIA)
NCT00430976
Pilot Observational Study Examining the Effect of Endocrine Therapy on Aging
University of Michigan
NCT05700006
Taste Perception and Chronic Disease Risk
Tufts University
NCT01023906
Epigenetics in the Aging Process
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00242255
The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders
Ohio University
NCT02505529
Increasing Physical Activity Among Sedentary Older Adults:What, Where, When, and With Whom
Brandeis University
NCT03124537
Muscle Anabolic Interventions to Accelerate Recovery From Hospitalization in Geriatric Patients
The University of Texas Medical Branch, Galveston
NCT02990533
Long-term Caloric Restriction and Cellular Aging Markers
University of California, San Francisco
NCT01256840
Health Enhancement And Resilience Training
University of California, San Francisco
NCT01959126
Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)
Amazentis
NCT03283462
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 29 |
| Phase 2 | 19 |
| Phase 3 | 6 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Aging records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Aging trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Aging page
263 registered trials, 126 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 126 Aging trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Florida sponsors the most Aging trials on record, review their full trial history before evaluating a specific study. See University of Florida's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Aging condition card totals 263 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.