Medical Information Only. Consult your healthcare provider before enrolling in any clinical trial.
Illinois: below-average open trial sites
2,290 of 6,854 in-state trials are recruiting (33%); below the 37% national average by 4 percentage points.
According to ClinicalTrials.gov-derived indexes, Illinois sits in the upper quartile of US states by in-state trial count (#7 of 52 states by registered in-state trial count).
Illinois: 6,854 US clinical trials with in-state sites, 2,290 recruiting.
Illinois has 6,854 registered US clinical trials with a study site in-state, 2,290 of them currently recruiting (below the 37% national average by 4 percentage points). 1,477 of these trials are in Phase 3 (late-stage) and 1,658 in Phase 2. The most frequently studied condition in Illinois is HIV Infections, with 152 linked trials.
Upper-quartile research density
Illinois sits in the upper quartile by in-state trial count. Open share is below the 37% national average by 4 percentage points - denser than most states, still short of the top-decile research hubs.
Below-average open enrollment
Illinois still shows 2,290 recruiting of 6,854 in-state trials (33% open), but below the 37% national average by 4 percentage points, so archived statuses weigh heavier than the national baseline.
- 33%
- open (below national share)
- 2,290
- still recruiting despite cool share
- 1,658
- Phase 2 rows in this footprint
- 152
- top: HIV Infections
Recruiting share is below the 37% national average by 4 percentage points. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
Illinois vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
6,854 Top 13% more indexed trials than 87% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for Illinois on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Illinois open-enrollment share sits below the national baseline.
2,290 of 6,854 in-state trials (33.4%) are recruiting, against 37% nationally (-3.6 percentage points). Counts include every study with at least one recorded site in the state.
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Chicago dominates Illinois's trial geography.
Chicago lists 4,968 of 6,854 in-state trials (72.5%) across 1,472 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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HIV Infections is the most-studied condition in Illinois.
152 of 6,854 in-state trials (2.2%) list HIV Infections. That is a local concentration figure, not a national disease ranking.
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Illinois sponsorship is fragmented across many organizations.
Northwestern University appears on 408 of 6,854 in-state trials (6%). Sponsor identity is as filed on ClinicalTrials.gov.
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2,980 Illinois trials carry a completed status.
2,980 of 6,854 (43.5%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 2,980 |
| Recruiting | 2,290 |
| Active | 1,584 |
By Phase
| Phase | Trial count |
|---|---|
| Phase 2 | 1,658 |
| NA | 1,574 |
| Phase 3 | 1,477 |
| Phase 1 | 882 |
| Phase 4 | 274 |
| Early Phase 1 | 49 |
Top Conditions
Top Sponsors
Where trials run in Illinois
Chicago carries 4,968 of Illinois's 6,854 indexed trials (72%) across 1,472 named sites, ahead of Evanston at 332. 8 cities clear five listed trials, together naming 2,026 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Chicago | 4,968 | 1,472 |
| Evanston | 332 | 111 |
| Peoria | 262 | 122 |
| Springfield | 245 | 102 |
| Maywood | 218 | 57 |
| Urbana | 151 | 35 |
| Skokie | 124 | 79 |
| Park Ridge | 102 | 48 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Volume high
Illinois indexes 6,854 in-state trials (p88 by registry volume among 52 states with sites).
Illinois: in-state trial volume sits in the high tercile
Geography is concentrated: Chicago alone accounts for 72% of Illinois's indexed trials (4,968 of 6,854), with Evanston a distant second at 332.
Phase mix: 1,477 Phase 3 vs 1,658 Phase 2 (balanced across stages).
Top condition: HIV Infections (152 trials); top sponsor Northwestern University (408).
high-volume · mid-open figures (6,854 trials · 33% open) describe registry geography under the volume high read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near Illinois on in-state trial volume
Cross-state peers under the volume high read (high-volume · mid-open), not the same-state browse list.
Similar high-volume hubs (± open share)
- Pennsylvania · 6,946 trials · 34% recruiting
- Ohio · 6,514 trials · 35% recruiting
- Massachusetts · 7,667 trials · 35% recruiting
- North Carolina · 5,625 trials · 33% recruiting
- Arizona · 5,607 trials · 30% recruiting
Similar mid-open peers (± trial volume)
- Tennessee · 33% recruiting · 3,520 trials
- Delaware · 33% recruiting · 652 trials
- New Jersey · 34% recruiting · 3,402 trials
- Maryland · 34% recruiting · 6,441 trials
- Florida · 33% recruiting · 10,986 trials