Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04908358 · ClinicalTrials.gov registry record · NA

The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance

A NA study of Aging, sponsored by Massachusetts General Hospital.

Active
Registry status
NA
Development phase
126
Enrollment target
1
Study location

NCT04908358 is a NA study of Aging that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 126 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04908358, a NA study of Aging, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
126 participants
Enrollment target
1
Study location

Study Summary

In this research study the investigators want to find out if a non-invasive electrical brain stimulation method called RAVANS (also called tVNS) can have a beneficial effect on cognition in older individuals. The investigators also want to understand whether certain individual factors contribute to the effect of RAVANS on cognition. RAVANS is only used in research studies.

Conditions Studied

Interventions

  • OTHER Active transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions
  • OTHER Sham transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Charlestown

Trial Details

FieldValue
Enrollment Target 126 participants
Start Date 2021-11-24
Est. Completion 2026-08-31
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT04908358

The ClinicalTrials.gov registry entry for NCT04908358 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 126 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (94% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Active transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions is the first listed.

NCT04908358 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04908358 about?

NCT04908358 is a clinical study titled "The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance". In this research study the investigators want to find out if a non-invasive electrical brain stimulation method called RAVANS (also called tVNS) can have a beneficial effect on cognition in older individuals. The investigators also want to understand whether certain individual factors contribute to ...

What is the current status of trial NCT04908358?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 126 participants. The study started on 2021-11-24. Estimated completion is 2026-08-31.

What conditions does trial NCT04908358 study?

This clinical trial studies the following conditions: Aging.

What interventions are being tested in trial NCT04908358?

The interventions under investigation include: Active transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions (OTHER), Sham transcutaneous vagus nerve stimulation respiratory-gated non-painful electrical stimulation of the auricle for 10 minute sessions (OTHER).

Who is sponsoring clinical trial NCT04908358?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04908358 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Aging

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.