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ClinicalTrials.gov 1,847 recruiting now official registry

Clinical trials in North Carolina

Every US clinical trial with a study site in North Carolina - recruiting status, phase mix, and the conditions and sponsors driving research in the state, from the NIH ClinicalTrials.gov registry.

North Carolina has 5,625 registered US clinical trials with a study site in-state, 1,847 of them currently recruiting (above the 14% national average by 19 percentage points). 890 of these trials are in Phase 3 (late-stage) and 1,270 in Phase 2. The most frequently studied condition in North Carolina is Breast Cancer, with 126 linked trials.

The state picture

North Carolina has 5,625 registered clinical trials with sites in-state, 1,847 of them open to new participants right now, about 33% of the state's indexed portfolio.

1,847
recruiting participants now
33%
of in-state trials open to enrollment
890
in Phase 3 (late-stage)
126
top condition: Breast Cancer

Counts include every study with at least one recorded site in the state, from the public ClinicalTrials.gov registry. Reference information, not medical advice.

NA1462Phase 21270Phase 3890Phase 1857Phase 4234Early Phase 144
Completed2684Recruiting1847Active1094
Treemap Treemap of 15 categories, sized proportional to value. Breast Cancer - 126 Breast Cancer 126 Obesity - 93 Obesity 93 Multiple Myeloma - 74 Multiple Myelo… 74 HIV Infections - 70 HIV Infections 70 Non-Small Cell Lung Cancer - 66 Non-Small Ce… 66 Cancer - 63 Cancer 63 Asthma - 62 Asthma 62 Prostate Cancer - 48 Prostate Cancer 48 Healthy - 46 Healthy 46 Colorectal Cancer - 44 Colorectal … 44 Heart Failure - 44 Heart Failure 44 Hypertension - 41 Hypertension 41 Rheumatoid Arthritis - 41 Rheumatoid Arthritis 41 Depression - 38 Depression 38 Lymphoma - 37 Lymphoma 37

By Status

StatusTrial count
Completed 2,684
Recruiting 1,847
Active 1,094

By Phase

PhaseTrial count
NA 1,462
Phase 2 1,270
Phase 3 890
Phase 1 857
Phase 4 234
Early Phase 1 44

Reading the Clinical Trial Landscape in North Carolina

ClinicalTrials.gov lists 5,625 clinical trials with study locations in North Carolina. Of those, 1,847 are currently recruiting, roughly 33% of the state's indexed portfolio, above the 14% national average by 19 percentage points, which is a rough but useful proxy for how much research activity is presently open to new participants relative to the rest of the country. The largest status group for North Carolina is "Completed" with 2,684 entries, which sets the overall tone of the registry footprint in this geography. These counts are drawn from the public registry maintained by the National Library of Medicine and are reflected here exactly as indexed; they include every study with at least one site recorded in North Carolina, regardless of sponsor type.

The phase distribution shown above breaks the same trials down by where they sit along the investigational pathway. For North Carolina, Phase 3 accounts for 890 indexed trials and Phase 2 accounts for 1,270. Phase 2 studies typically evaluate early efficacy and refine dosing, while Phase 3 studies run larger and are usually closer to regulatory submission, so a state with a strong Phase 3 count often reflects established research centers working on late-stage programs, while a heavier Phase 1 and Phase 2 weighting can indicate concentrations of academic medical centers and early-stage investigator networks. Phase markers come directly from the sponsor-reported registry field and are not transformed on this site.

The most frequently indexed condition for North Carolina is Breast Cancer with 126 linked trials, across 15 top condition areas surfaced above. On the sponsor side, Duke University leads with 496 studies tied to North Carolina, with 9 additional organizations in the visible top list. Together, these breakdowns give a quick sense of which conditions and organizations drive trial activity in North Carolina, but they do not describe treatment availability, local clinic capacity, or the chance of being matched to any specific study. All numbers come from ClinicalTrials.gov and should be used for reference only, verify current status and eligibility directly on ClinicalTrials.gov, and always discuss clinical trial participation with a qualified healthcare provider before making any decision.

What this means if you're in North Carolina

1,847 trials in North Carolina are open to new participants, here's how to act on that.

A trial is counted here when it lists at least one in-state site; always confirm eligibility and current status on ClinicalTrials.gov.

States With a Similar Recruiting Share

The closest states nationwide to North Carolina's 33% of trials currently recruiting.

Source: ClinicalTrials.gov, the US trial registry maintained by the National Library of Medicine, part of the NIH. See our methodology for how this data is sourced and computed.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered clinical trial within this state, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.