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NCT07354620 · ClinicalTrials.gov registry record · Early Phase 1

A Pilot Study on Reverse Aging (The REVERSE Study)

A Early Phase 1 study of Aging, sponsored by The Christ Hospital.

Active
Registry status
Early Phase 1
Development phase
52
Enrollment target
1
Study location

NCT07354620 is a Early Phase 1 study of Aging that is active but no longer recruiting, run by The Christ Hospital. The registered enrollment target is 52 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07354620, a Early Phase 1 study of Aging, is active but no longer recruiting, sponsored by The Christ Hospital.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
52 participants
Enrollment target
1
Study location

Study Summary

Aging can be defined as a time-dependent functional decline in physiological function, which may increase the vulnerability to diseases and eventually death. The question is whether aging is a normal process, or exists as an "uber-illness?" Work done by Dr Sinclair at Harvard suggests the latter. Dr. Sinclair feels people should be able to age-in-place, or even reverse age. Aging is arguably the single biggest risk factor for all acquired and chronic diseases. Delaying the aging rate by 7 years would cut the incidence of chronic disease in half! Up until know the effects of anti-aging would need longitudinal studies until death. Now, with the advent of a 3rd generation OMIC Age clock, there is a way to assess if an intervention is changing the rate of aging and other methylation patterns associated with aging.

Conditions Studied

Aging

Interventions

  • DRUG Rapamycin (Tablets)
  • DIETARY_SUPPLEMENT Prolon diet

Study Locations (1)

Ohio

  • AIM for Wellbeing - Cincinnati

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2025-02-15
Est. Completion 2026-05
Phase Early Phase 1

Sponsor

The Christ Hospital

13 total trials

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What the Registry Record Tells You About NCT07354620

The ClinicalTrials.gov registry entry for NCT07354620 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (98% lower). The listed sponsor is The Christ Hospital, which has 13 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Rapamycin (Tablets) is the first listed.

NCT07354620 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT07354620 about?

NCT07354620 is a clinical study titled "A Pilot Study on Reverse Aging (The REVERSE Study)". Aging can be defined as a time-dependent functional decline in physiological function, which may increase the vulnerability to diseases and eventually death. The question is whether aging is a normal process, or exists as an "uber-illness?" Work done by Dr Sinclair at Harvard suggests the latter. Dr...

What is the current status of trial NCT07354620?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 52 participants. The study started on 2025-02-15. Estimated completion is 2026-05.

What conditions does trial NCT07354620 study?

This clinical trial studies the following conditions: Aging.

What interventions are being tested in trial NCT07354620?

The interventions under investigation include: Rapamycin (Tablets) (DRUG), Prolon diet (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT07354620?

This trial is sponsored by The Christ Hospital, which has 13 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07354620 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.