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NCT06133634 · ClinicalTrials.gov registry record · Phase 1
Fisetin to Improve Vascular Function in Older Adults
A Phase 1 study of Aging and Endothelial Dysfunction, sponsored by University of Colorado, Boulder.
- Active
- Registry status
- Phase 1
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT06133634 is a Phase 1 study of Aging and Endothelial Dysfunction that is active but no longer recruiting, run by University of Colorado, Boulder. The registered enrollment target is 70 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06133634, a Phase 1 study of Aging and Endothelial Dysfunction, is active but no longer recruiting, sponsored by University of Colorado, Boulder.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a pilot clinical trial to test the efficacy of intermittent treatment with the flavonoid compound fisetin for improving vascular endothelial function and reducing aortic stiffness in older adults. This trial will also determine the potential mechanisms by which fisetin may improve vascular function, including by decreasing mitochondrial oxidative stress, cellular senescence and senescence-associated secretory phenotype (SASP) factors in circulation. Lastly, safety, tolerability and adherence of fisetin treatment will be assessed.
Conditions Studied
Interventions
- OTHER Placebo
- DIETARY_SUPPLEMENT Fisetin
Study Locations (1)
Colorado
- University of Colorado Boulder - Boulder
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2023-09-25 |
| Est. Completion | 2027-03-31 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06133634
The ClinicalTrials.gov registry entry for NCT06133634 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The listed sponsor is University of Colorado, Boulder, which has 69 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06133634 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.
Frequently Asked Questions
What is clinical trial NCT06133634 about?
NCT06133634 is a clinical study titled "Fisetin to Improve Vascular Function in Older Adults". This is a pilot clinical trial to test the efficacy of intermittent treatment with the flavonoid compound fisetin for improving vascular endothelial function and reducing aortic stiffness in older adults. This trial will also determine the potential mechanisms by which fisetin may improve vascular f...
What is the current status of trial NCT06133634?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2023-09-25. Estimated completion is 2027-03-31.
What conditions does trial NCT06133634 study?
This clinical trial studies the following conditions: Aging, Endothelial Dysfunction, Arterial Stiffness.
What interventions are being tested in trial NCT06133634?
The interventions under investigation include: Placebo (OTHER), Fisetin (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT06133634?
This trial is sponsored by University of Colorado, Boulder, which has 69 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06133634 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.