Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 1 of 57

RECRUITING NA

Impact of Cryotherapy Spray (Tru-Freeze) for the Eradication of Gastric Antral Vascular Ectasia (ICE-GAVE)

NCT07169799

RECRUITING Phase 4

Erector Spinae Plane Block Versus Trigger Point Injection for Chronic Thoracic Myofascial Pain

NCT07632820

RECRUITING NA

A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia

NCT07526766

RECRUITING NA

COMPARE-VENT Feasibility Pilot Study

NCT07656259

RECRUITING Phase 1

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

NCT07468136

RECRUITING NA

Health and Wellness Coaching to Improve Adherence to Healthy Habits and Treatment Plans in Papillary and Follicular Thyroid Cancer Survivors

NCT07545837

RECRUITING NA

Virtual Group Resilient Living Program For Patients Living With Advanced Cancer

NCT07659158

RECRUITING

Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer

NCT07527143

RECRUITING NA

Thalamus Seizure Detection With a Deep Brain Stimulator System

NCT06700356

RECRUITING NA

A Study Of Starting Strength Barbell Training

NCT07578285

RECRUITING Phase 1

AAVrh10-PCCA Gene Therapy for Propionic Acidemia

NCT07643844

RECRUITING

A Study Of Remote Voice Analysis Tool For Diagnosing And Monitoring ME/CFS

NCT07551999

RECRUITING Phase 1

HEART: Pilot Randomized Controlled Trial

NCT07483177

RECRUITING Phase 2

Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients

NCT07460752

RECRUITING Phase 1

Pharmacokinetics Of Emulsified Avacopan Applied By NG Tube

NCT07556484

RECRUITING Phase 1

Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

NCT07456852

RECRUITING

A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease

NCT07483203

RECRUITING Early Phase 1

FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing Disease

NCT07460232

RECRUITING NA

Virtual Reality in Reducing Acute Orthopedic Pain

NCT06624969

RECRUITING Phase 2

VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma

NCT07510334

RECRUITING NA

Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial

NCT07618273

RECRUITING NA

Acute Kidney Injury In Care Transitions (ACT): Pragmatic Clinical Trial

NCT07670520

RECRUITING Phase 2

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

NCT07487818

RECRUITING NA

A Study Of Milk Consumption In Metabolic Syndrome

NCT07401888

RECRUITING Phase 2

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

NCT07301268

RECRUITING NA

A Screening Program to Improve the Early Detection of Sporadic Pancreatic Cancer in Individuals With a High-Risk of Developing Pancreatic Cancer

NCT07324096

RECRUITING Phase 2

An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors

NCT06667726

RECRUITING NA

Comparing Acoustic Resonance Therapy (ART) vs. Cognitive Behavioral Therapy for Insomnia (CBT-I)

NCT07486882

RECRUITING Phase 4

Itraconazole Therapy In Bronchiectasis With Airway Mold

NCT07283497

RECRUITING

Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting

NCT07344714

RECRUITING Phase 4

A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects

NCT07285863

RECRUITING NA

A Study Of Heart Disease Using AI-Enabled Electrocardiography And Focused Cardiac Ultrasound

NCT07351656

RECRUITING NA

Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

NCT07210411

RECRUITING Phase 2

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

NCT06333652

RECRUITING

Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction

NCT07401771

RECRUITING NA

A Study Of Auricular Transcutaneous Vagus Nerve Stimulation In Chronic Dizziness

NCT07420803

RECRUITING

A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation

NCT07308704

RECRUITING NA

Enhancing Brain And Mental Health Through Breathing Practice

NCT07369752

RECRUITING Phase 4

RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)

NCT07266545

RECRUITING

Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer

NCT07477886

RECRUITING NA

Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease

NCT07222475

RECRUITING Phase 4

Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

NCT07174349

RECRUITING NA

Remote Assessment of Digital Neurologic Testing

NCT07014982

RECRUITING NA

Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain

NCT07278570

RECRUITING NA

Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI

NCT07210437

RECRUITING NA

Electronic Approach to the Human Massage Therapist

NCT07040397

RECRUITING Early Phase 1

68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease

NCT07273188

RECRUITING Phase 4

A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi

NCT07223580

RECRUITING Phase 1

Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer

NCT06997094

RECRUITING NA

AI-Guided Left Bundle Branch Area Pacing

NCT07206602

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.