Mayo Clinic
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count).
Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.
Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.
Top-decile sponsor footprint
Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,816 of 2,102 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
2,844 total, page 1 of 57
Impact of Cryotherapy Spray (Tru-Freeze) for the Eradication of Gastric Antral Vascular Ectasia (ICE-GAVE)
NCT07169799
Erector Spinae Plane Block Versus Trigger Point Injection for Chronic Thoracic Myofascial Pain
NCT07632820
A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia
NCT07526766
COMPARE-VENT Feasibility Pilot Study
NCT07656259
Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas
NCT07468136
Health and Wellness Coaching to Improve Adherence to Healthy Habits and Treatment Plans in Papillary and Follicular Thyroid Cancer Survivors
NCT07545837
Virtual Group Resilient Living Program For Patients Living With Advanced Cancer
NCT07659158
Acceptability of Testing DNA Markers in Vaginal Fluid for the Detection of Endometrial Cancer
NCT07527143
Thalamus Seizure Detection With a Deep Brain Stimulator System
NCT06700356
A Study Of Starting Strength Barbell Training
NCT07578285
AAVrh10-PCCA Gene Therapy for Propionic Acidemia
NCT07643844
A Study Of Remote Voice Analysis Tool For Diagnosing And Monitoring ME/CFS
NCT07551999
HEART: Pilot Randomized Controlled Trial
NCT07483177
Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients
NCT07460752
Pharmacokinetics Of Emulsified Avacopan Applied By NG Tube
NCT07556484
Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy
NCT07456852
A Study Of Clinical Implications Of Pulmonary Vascular Disease In Valvular Heart Disease
NCT07483203
FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing Disease
NCT07460232
Virtual Reality in Reducing Acute Orthopedic Pain
NCT06624969
VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma
NCT07510334
Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial
NCT07618273
Acute Kidney Injury In Care Transitions (ACT): Pragmatic Clinical Trial
NCT07670520
A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation
NCT07487818
A Study Of Milk Consumption In Metabolic Syndrome
NCT07401888
GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma
NCT07301268
A Screening Program to Improve the Early Detection of Sporadic Pancreatic Cancer in Individuals With a High-Risk of Developing Pancreatic Cancer
NCT07324096
An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors
NCT06667726
Comparing Acoustic Resonance Therapy (ART) vs. Cognitive Behavioral Therapy for Insomnia (CBT-I)
NCT07486882
Itraconazole Therapy In Bronchiectasis With Airway Mold
NCT07283497
Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting
NCT07344714
A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects
NCT07285863
A Study Of Heart Disease Using AI-Enabled Electrocardiography And Focused Cardiac Ultrasound
NCT07351656
Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury
NCT07210411
Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders
NCT06333652
Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction
NCT07401771
A Study Of Auricular Transcutaneous Vagus Nerve Stimulation In Chronic Dizziness
NCT07420803
A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation
NCT07308704
Enhancing Brain And Mental Health Through Breathing Practice
NCT07369752
RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)
NCT07266545
Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer
NCT07477886
Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease
NCT07222475
Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery
NCT07174349
Remote Assessment of Digital Neurologic Testing
NCT07014982
Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain
NCT07278570
Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI
NCT07210437
Electronic Approach to the Human Massage Therapist
NCT07040397
68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease
NCT07273188
A Study Of Corticosteroid On Postoperative Pain After Ureteroscopy For Urinary Calculi
NCT07223580
Decitabine in Combination With Standard of Care Therapy for the Treatment of Surgically Resectable HPV-Negative Head and Neck Cancer
NCT06997094
AI-Guided Left Bundle Branch Area Pacing
NCT07206602
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 435 |
| Phase 2 | 386 |
| Phase 3 | 86 |
| Phase 4 | 166 |
Therapeutic Areas
What is open in the Mayo Clinic pipeline
544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).
Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).
Top condition: Healthy (36 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Mayo Clinic: open-pipeline peers nationwide
Peers matched on 2,844 registered trials and 19% open enrollment, not the therapeutic-area sidebar.
Mayo Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 2,844 trials (± recruiting share)
- M.D. Anderson Cancer Center · 2,692 trials · 20% recruiting
- National Cancer Institute (NCI) · 3,257 trials · 10% recruiting
- Massachusetts General Hospital · 2,032 trials · 17% recruiting
- National Institute of Allergy and Infectious Diseases (NIAID) · 2,006 trials · 8% recruiting
Sponsors near 19% open enrollment (± trial volume)
- University of South Carolina · 19% recruiting · 157 trials
- Vanderbilt University Medical Center · 19% recruiting · 677 trials
- MemorialCare Health System · 19% recruiting · 21 trials
- University of North Texas Health Science Center · 19% recruiting · 21 trials
Related
What to do with this Mayo Clinic page
2,844 registered trials is a research-attention snapshot, not an endorsement of Mayo Clinic or any single study.
- 544 of Mayo Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Healthy is the condition Mayo Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Mayo Clinic pipeline card: 2,844 registered trials from official public datasets.Report a data error.