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NCT06798571 · ClinicalTrials.gov registry record · Phase 4
Role of Menopause in Thermoregulation
A Phase 4 study of Aging and Menopause, sponsored by Penn State University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT06798571: Recruiting Phase 4 study of Aging and Menopause, sponsored by Penn State University.
NCT06798571 is a Phase 4 study of Aging and Menopause that is actively recruiting participants, run by Penn State University. The registered enrollment target is 24 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06798571, a Phase 4 study of Aging and Menopause, is actively recruiting participants, sponsored by Penn State University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group and age matched men. Aging and reproductive hormones, specifically estrogen, independently alter responses to heat stress. However, the combined effects of low estrogen following menopause and aging on the response to heat stress are unknown. In this study, the investigators will identify the role of estrogen in pre and post menopausal women on thermoregulatory responses to heat stress.
Primary Outcome
Skin blood flow response to whole body heating is continuously monitored
Interventions
- DRUG Elagolix Oral Tablet
- DRUG Estradiol patch
- OTHER cellulose placebo
- OTHER placebo patch
Study Locations (1)
Pennsylvania
- Noll Laboratory - University Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-03-01 |
| Est. Completion | 2026-07-01 |
| Phase | Phase 4 |
What NCT06798571 shows while recruiting
NCT06798571 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 4 interventions - of which Elagolix Oral Tablet is the first listed.
NCT06798571 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06798571 about?
NCT06798571 is a clinical study titled "Role of Menopause in Thermoregulation". The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group an...
What is the current status of trial NCT06798571?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2025-03-01. Estimated completion is 2026-07-01.
What conditions does trial NCT06798571 study?
This clinical trial studies the following conditions: Aging, Menopause.
What interventions are being tested in trial NCT06798571?
The interventions under investigation include: Elagolix Oral Tablet (DRUG), Estradiol patch (DRUG), cellulose placebo (OTHER), placebo patch (OTHER).
Who is sponsoring clinical trial NCT06798571?
This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06798571 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06798571's enrollment target sits among peer trials
24 214th of 262 higher than 40 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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