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NCT06798571 · ClinicalTrials.gov registry record · Phase 4

Role of Menopause in Thermoregulation

A Phase 4 study of Aging and Menopause, sponsored by Penn State University.

Recruiting
Registry status
Phase 4
Development phase
24
Enrollment target
1
Study location

NCT06798571 is a Phase 4 study of Aging and Menopause that is actively recruiting participants, run by Penn State University. The registered enrollment target is 24 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06798571, a Phase 4 study of Aging and Menopause, is actively recruiting participants, sponsored by Penn State University.

RECRUITING
Registry status
Phase 4
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group and age matched men. Aging and reproductive hormones, specifically estrogen, independently alter responses to heat stress. However, the combined effects of low estrogen following menopause and aging on the response to heat stress are unknown. In this study, the investigators will identify the role of estrogen in pre and post menopausal women on thermoregulatory responses to heat stress.

Conditions Studied

Interventions

  • DRUG Elagolix Oral Tablet
  • DRUG Estradiol patch
  • OTHER cellulose placebo
  • OTHER placebo patch

Study Locations (1)

Pennsylvania

  • Noll Laboratory - University Park

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2025-03-01
Est. Completion 2026-07-01
Phase Phase 4

Sponsor

Penn State University

219 total trials

What the Registry Record Tells You About NCT06798571

The ClinicalTrials.gov registry entry for NCT06798571 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The listed sponsor is Penn State University, which has 219 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 4 interventions - of which Elagolix Oral Tablet is the first listed.

NCT06798571 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06798571 about?

NCT06798571 is a clinical study titled "Role of Menopause in Thermoregulation". The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events. Previous heat waves report that women over 65 experience worse health outcomes than any other age group an...

What is the current status of trial NCT06798571?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 24 participants. The study started on 2025-03-01. Estimated completion is 2026-07-01.

What conditions does trial NCT06798571 study?

This clinical trial studies the following conditions: Aging, Menopause.

What interventions are being tested in trial NCT06798571?

The interventions under investigation include: Elagolix Oral Tablet (DRUG), Estradiol patch (DRUG), cellulose placebo (OTHER), placebo patch (OTHER).

Who is sponsoring clinical trial NCT06798571?

This trial is sponsored by Penn State University, which has 219 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06798571 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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