Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Aging: early-phase trial registry
126 of 263 indexed Aging trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #38 of 28,707 conditions by registered trial count.
263 US clinical trials · 126 currently recruiting · #38 of 28,707 conditions by registered trial count
Aging: 263 US clinical trials tracked, 126 recruiting.
Aging is the subject of 263 registered US clinical trials on ClinicalTrials.gov, 126 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 48 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 14 of these trials.
Enrollment posture brief
Registry condition aging
OPEN 126 | RECR 48% | LATE 14 | EARLY 48 | RANK #38 | SPON 14
Volume-matched condition peers
Nearest open-share peer: Lung Non-Small Cell Carcinoma (48% recruiting · 48 trials)
Aging lists 126 open slots (48% of 263 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Aging on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Aging is recruiting above its size-band peers.
126 of 263 indexed trials (47.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Aging trials is spread across many organizations.
University of Florida accounts for 14 of 263 trials (5.3%). 132 distinct sponsors appear on at least one study for this condition label.
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Most Aging trials plan to enrol fewer than 100 people.
Median target enrolment is 66 among the 263 trials that report a genuine target (sentinel values excluded). 166 of those (63.1%) plan for fewer than 100 participants.
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Aging research is mostly interventional.
228 interventional and 35 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
263 total, page 2 of 6
Cardiometabolic Consequences of the Loss of Ovarian Function
University of Colorado, Denver
NCT06264882
Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older
Wake Forest University Health Sciences
NCT05858034
Metabolic and Functional Consequences of Aging in Health and Disease
Texas A&M University
NCT05240885
Mindfulness for Cognition in Early-stage Alzheimer's Disease
VA Boston Healthcare System
NCT06792877
Multimodal Musical Stimulation for Healthy Neurocognitive Aging
Northeastern University
NCT06229093
Heat Waves and the Elderly - Cooling Modalities
University of Texas Southwestern Medical Center
NCT05484739
Speech Perception and High Cognitive Demand
University of Maryland, College Park
NCT04997577
Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults
University of California, San Francisco
NCT06633978
Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise
University of Colorado, Boulder
NCT05000515
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Georgia Institute of Technology
NCT03896529
Empagliflozin Reversal of Arterial StiffnEss in Aging
University of Missouri-Columbia
NCT06506422
Emotional Well-being and Measures of Healthy Aging
Northwestern University
NCT07334106
Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults
Oregon State University
NCT06942351
Molecular Optimization Via Exercise (MOVE)
Buck Institute for Research on Aging
NCT06540287
IH, Brain Health, and T2D
Darren P Casey
NCT07173543
The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
Wright State University
NCT06428721
A Deep Longitudinal Analysis of Next Generation Influenza Vaccines in Older Adults
The Jackson Laboratory
NCT05518500
Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
University of Missouri-Columbia
NCT06417177
Cognitive Remediation
Cutter Lindbergh
NCT07171450
Postural Control During Concurrent Cognitive Tasks During Optic Flow Stimulation
Chia-Cheng Lin, PhD, PT, MSPT
NCT05117463
Effects of Obesity in the Aged
University of Texas Southwestern Medical Center
NCT05028309
Feasibility of Home-based tES for Older Adults at Risk of Falling
Hebrew SeniorLife
NCT04732533
Rapalog Pharmacology (RAP PAC) Study
University of Wisconsin, Madison
NCT05949658
Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
Wright State University
NCT03906253
Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse
Joel Trinity
NCT04351113
Using Reinforcement Learning to Personalize Electronic Health Record Tools to Facilitate Deprescribing
Brigham and Women's Hospital
NCT06660979
Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging
University of Florida
NCT05457725
Optimizing Strength Training in Older Adults
Queens College, The City University of New York
NCT06812143
Acetate and Age-associated Arterial Dysfunction
University of Colorado, Denver
NCT05424263
Early Neurovascular Adaptations in Aging Women
University of Missouri-Columbia
NCT06520982
The Role of Neutrophils in the Age-driven Decline in Anti-pneumococcal Vaccine Responses
State University of New York at Buffalo
NCT06128915
Effect of Snacks on Aging
University of California, Los Angeles
NCT06879626
MTOR Inhibitors in Older Adults
University of Texas Southwestern Medical Center
NCT06727305
Fatty Acid Modulation of Brain Function in Older Adults
University of Vermont
NCT06192407
The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
UConn Health
NCT06027554
Ischemic Conditioning to Promote Microvascular Resiliency in Frail Individuals
Medical College of Wisconsin
NCT05808686
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
The University of Texas at Arlington
NCT05522075
Breaking Sitting with High-intensity Interval Training for Brain Health
University of Illinois at Urbana-Champaign
NCT06243016
The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
AdventHealth Translational Research Institute
NCT03761446
Using Nicotine to Reverse Age-related Auditory Processing Deficits
University of California, Irvine
NCT04971954
Effects of Nicotine and Attention on Frequency Tuning in Auditory Cortex
University of California, Berkeley
NCT05018117
Transient Receptor Potential Channels
Penn State University
NCT06444594
Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities
Brigham and Women's Hospital
NCT06989619
Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults
Scott Silveira
NCT07144527
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
University of California, Berkeley
NCT06367738
Preliminary Testing of Cafe Move for Primary Prevention of Physical Frailty
University of Montana
NCT05720507
Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans
University of Alabama at Birmingham
NCT06217575
Effect of a Daily Supplement on Plasma PAI-1 Levels
University of California, Los Angeles
NCT07469475
Fisetin to Reduce Senescence and Mobility Impairment in PAD
Northwestern University
NCT06399809
Pain and Split-belt Motor Learning in Older Adults
University of Delaware
NCT07054840
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 29 |
| Phase 2 | 19 |
| Phase 3 | 6 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Aging records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Aging trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Aging page
263 registered trials, 126 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 126 Aging trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Florida sponsors the most Aging trials on record, review their full trial history before evaluating a specific study. See University of Florida's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Aging condition card totals 263 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.