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NCT06582680 · ClinicalTrials.gov registry record · Phase 4
Aging, Beta Blockers, and Thermoregulatory Responses
A Phase 4 study of Aging and Heat Stress, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT06582680: Recruiting Phase 4 study of Aging and Heat Stress, sponsored by University of Texas Southwestern Medical Center.
NCT06582680 is a Phase 4 study of Aging and Heat Stress that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 22 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06582680, a Phase 4 study of Aging and Heat Stress, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.
Primary Outcome
The change in internal temperature to the 3-hour heat exposure will be measured.
Conditions Studied
Interventions
- OTHER Ambient Heat
Study Locations (1)
Texas
- IEEM Texas Health Presbyterian Hospital Dallas - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2024-10-04 |
| Est. Completion | 2026-09-30 |
| Phase | Phase 4 |
What NCT06582680 shows while recruiting
NCT06582680 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Ambient Heat is the first listed.
NCT06582680 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06582680 about?
NCT06582680 is a clinical study titled "Aging, Beta Blockers, and Thermoregulatory Responses". This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.
What is the current status of trial NCT06582680?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 22 participants. The study started on 2024-10-04. Estimated completion is 2026-09-30.
What conditions does trial NCT06582680 study?
This clinical trial studies the following conditions: Aging, Heat Stress.
What interventions are being tested in trial NCT06582680?
The interventions under investigation include: Ambient Heat (OTHER).
Who is sponsoring clinical trial NCT06582680?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06582680 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06582680's enrollment target sits among peer trials
22 226th of 262 higher than 33 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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