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NCT06534450 · ClinicalTrials.gov registry record · Phase 3

The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics

A Phase 3 study of Aging, sponsored by Dobri Kiprov.

Active
Registry status
Phase 3
Development phase
40
Enrollment target
1
Study location

NCT06534450 is a Phase 3 study of Aging that is active but no longer recruiting, run by Dobri Kiprov. The registered enrollment target is 40 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06534450, a Phase 3 study of Aging, is active but no longer recruiting, sponsored by Dobri Kiprov.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to assure the safety of long term therapeutic plasma exchange (TPE) with and without Intravenous Immunoglobulin (IVIG) and its effects on biomarkers and epigenetic biologic clocks in forty individuals. The main question is to assure the safety from long term TPE using changes in clinical and laboratory outcomes and also evaluating changes on additional blood biomarkers and epigenetic clocks during and after TPE treatment. Researchers will compare the TPE treatment group to the Sham treatment group to identify changes due to TPE. Participants will receive six TPE or Sham treatments over one of two treatment schedules and may receive IVIG with treatment.

Conditions Studied

Interventions

  • DEVICE Sham
  • DRUG IVIG
  • DEVICE Therapeutic Plasma Exchange

Study Locations (1)

California

  • Global Apheresis - Mill Valley

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2022-09-12
Est. Completion 2025-08
Phase Phase 3

Sponsor

Dobri Kiprov

1 total trials

What the Registry Record Tells You About NCT06534450

The ClinicalTrials.gov registry entry for NCT06534450 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (98% lower). The listed sponsor is Dobri Kiprov, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 3 interventions - of which Sham is the first listed.

NCT06534450 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06534450 about?

NCT06534450 is a clinical study titled "The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics". The goal of this clinical trial is to assure the safety of long term therapeutic plasma exchange (TPE) with and without Intravenous Immunoglobulin (IVIG) and its effects on biomarkers and epigenetic biologic clocks in forty individuals. The main question is to assure the safety from long term TPE us...

What is the current status of trial NCT06534450?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 40 participants. The study started on 2022-09-12. Estimated completion is 2025-08.

What conditions does trial NCT06534450 study?

This clinical trial studies the following conditions: Aging.

What interventions are being tested in trial NCT06534450?

The interventions under investigation include: Sham (DEVICE), IVIG (DRUG), Therapeutic Plasma Exchange (DEVICE).

Who is sponsoring clinical trial NCT06534450?

This trial is sponsored by Dobri Kiprov, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06534450 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.