Medical Information Only. Consult your healthcare provider before enrolling in any clinical trial.
Maryland: below-average open trial sites
2,178 of 6,441 in-state trials are recruiting (34%); below the 37% national average by 3 percentage points.
According to ClinicalTrials.gov-derived indexes, Maryland sits in the upper quartile of US states by in-state trial count (#9 of 52 states by registered in-state trial count).
Maryland: 6,441 US clinical trials with in-state sites, 2,178 recruiting.
Maryland has 6,441 registered US clinical trials with a study site in-state, 2,178 of them currently recruiting (below the 37% national average by 3 percentage points). 999 of these trials are in Phase 3 (late-stage) and 1,467 in Phase 2. The most frequently studied condition in Maryland is HIV Infections, with 126 linked trials.
Upper-quartile research density
Maryland sits in the upper quartile by in-state trial count. Open share is below the 37% national average by 3 percentage points - denser than most states, still short of the top-decile research hubs.
Below-average open enrollment
Maryland still shows 2,178 recruiting of 6,441 in-state trials (34% open), but below the 37% national average by 3 percentage points, so archived statuses weigh heavier than the national baseline.
- 34%
- open (below national share)
- 2,178
- still recruiting despite cool share
- 1,467
- Phase 2 rows in this footprint
- 126
- top: HIV Infections
Recruiting share is below the 37% national average by 3 percentage points. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
Maryland vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
6,441 Top 17% more indexed trials than 83% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for Maryland on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Maryland open-enrollment share sits below the national baseline.
2,178 of 6,441 in-state trials (33.8%) are recruiting, against 37% nationally (-3.2 percentage points). Counts include every study with at least one recorded site in the state.
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Baltimore dominates Maryland's trial geography.
Baltimore lists 3,582 of 6,441 in-state trials (55.6%) across 1,140 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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HIV Infections is the most-studied condition in Maryland.
126 of 6,441 in-state trials (2%) list HIV Infections. That is a local concentration figure, not a national disease ranking.
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Maryland sponsorship is fragmented across many organizations.
National Cancer Institute (NCI) appears on 529 of 6,441 in-state trials (8.2%). Sponsor identity is as filed on ClinicalTrials.gov.
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3,101 Maryland trials carry a completed status.
3,101 of 6,441 (48.1%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 3,101 |
| Recruiting | 2,178 |
| Active | 1,162 |
By Phase
| Phase | Trial count |
|---|---|
| Phase 2 | 1,467 |
| Phase 1 | 1,180 |
| NA | 1,054 |
| Phase 3 | 999 |
| Phase 4 | 211 |
| Early Phase 1 | 45 |
Top Conditions
Top Sponsors
Where trials run in Maryland
Baltimore carries 3,582 of Maryland's 6,441 indexed trials (56%) across 1,140 named sites, ahead of Bethesda at 1,993. 8 cities clear five listed trials, together naming 1,809 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Baltimore | 3,582 | 1,140 |
| Bethesda | 1,993 | 244 |
| Rockville | 234 | 154 |
| Silver Spring | 99 | 53 |
| Hagerstown | 98 | 56 |
| Chevy Chase | 97 | 59 |
| Columbia | 92 | 57 |
| Towson | 79 | 46 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Trial size large
Maryland's in-state trials target 9,707 patients on average (p86 by trial size among 52 states with enrollment data), larger, multi-site studies than most states.
Maryland: in-state trial volume sits in the high tercile
Sites spread across 8 cities with five or more listed trials, led by Baltimore (3,582, 56% of the state total) and Bethesda (1,993), together naming 1,809 distinct research locations.
Phase mix: 999 Phase 3 vs 1,467 Phase 2 (balanced across stages).
Top condition: HIV Infections (126 trials); top sponsor National Cancer Institute (NCI) (529).
high-volume · high-open figures (6,441 trials · 34% open) describe registry geography under the trial size large read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near Maryland on in-state trial volume
Cross-state peers under the trial size large read (high-volume · high-open), not the same-state browse list.
Similar high-volume hubs (± open share)
- Ohio · 6,514 trials · 35% recruiting
- North Carolina · 5,625 trials · 33% recruiting
- Arizona · 5,607 trials · 30% recruiting
- Colorado · 5,273 trials · 31% recruiting
- Massachusetts · 7,667 trials · 35% recruiting
Similar high-open peers (± trial volume)
- Oregon · 34% recruiting · 1,999 trials
- New Jersey · 34% recruiting · 3,402 trials
- Pennsylvania · 34% recruiting · 6,946 trials
- Delaware · 33% recruiting · 652 trials
- Illinois · 33% recruiting · 6,854 trials