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NCT06519877 · ClinicalTrials.gov registry record · Phase 2

Fiber and Calcium Absorption in Older Men

A Phase 2 study of Aging, sponsored by VA Office of Research and Development.

Recruiting
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT06519877: Recruiting Phase 2 study of Aging, sponsored by VA Office of Research and Development.

NCT06519877 is a Phase 2 study of Aging that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 30 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06519877, a Phase 2 study of Aging, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for age-related bone loss in men. Preclinical and human studies in adolescents and postmenopausal women suggest that dietary fiber intake influences bone metabolism by modulating the gut microbiome to augment intestinal calcium absorption, but it is unclear through what molecular mechanism and whether dietary fiber has the same effects in older men. In this crossover intervention study, the investigators will enroll and follow 30 older male Veterans to evaluate the effects of soluble corn fiber on intestinal calcium absorption and explore the contribution of the gut microbiome.

Primary Outcome

Dual stable calcium isotopic tracer method

Conditions Studied

Interventions

  • DIETARY_SUPPLEMENT Soluble corn fiber

Study Locations (1)

California

  • San Francisco VA Medical Center, San Francisco, CA - San Francisco

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-01-01
Est. Completion 2029-01-01
Phase Phase 2
VA Office of Research and Development

1,668 total trials

What NCT06519877 shows while recruiting

NCT06519877 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Soluble corn fiber is the first listed.

NCT06519877 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06519877 about?

NCT06519877 is a clinical study titled "Fiber and Calcium Absorption in Older Men". Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for age-related bone loss in men. Preclinical and human studies in adolescents and postmenopausal women suggest that dietary fiber intake influen...

What is the current status of trial NCT06519877?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2025-01-01. Estimated completion is 2029-01-01.

What conditions does trial NCT06519877 study?

This clinical trial studies the following conditions: Aging.

What interventions are being tested in trial NCT06519877?

The interventions under investigation include: Soluble corn fiber (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT06519877?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06519877 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Aging

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06519877's enrollment target sits among peer trials

30 193rd of 262 higher than 60 of 262 other Aging trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06519877, the US trial registry maintained by the National Library of Medicine. NCT06519877 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.