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NCT05532657 · ClinicalTrials.gov registry record · Phase 3
ACHIEVE Brain Health Follow-Up Study
A Phase 3 study of Aging and Mild Cognitive Impairment, sponsored by Johns Hopkins University.
- Active
- Registry status
- Phase 3
- Development phase
- 629
- Enrollment target
- 4
- Study locations
NCT05532657: Active Phase 3 study of Aging and Mild Cognitive Impairment, sponsored by Johns Hopkins University.
NCT05532657 is a Phase 3 study of Aging and Mild Cognitive Impairment that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 629 participants, below the 2,192-participant average among 262 other Aging trials with a reported enrollment target (71% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05532657, a Phase 3 study of Aging and Mild Cognitive Impairment, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 629 participants
- Enrollment target
- 4
- Study locations
Study Summary
The ACHIEVE Brain Health Follow-Up Study is a 3-year follow-up to the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized study to determine the long-term effect of hearing intervention vs. successful aging/delayed hearing intervention on rates of cognitive decline and incident mild cognitive impairment or dementia.
Primary Outcome
Change from original ACHIEVE trial baseline to ACHIEVE-BHFU final visit in global cognition, as assessed using a factor score derived from completion of a neurocognitive testing battery. The ACHIEVE and ACHIEVE Brain Health studies administer a neurocognitive testing battery annually, which includes the following cognitive tests: Delayed Word Recall, Incidental Learning, Logical Memory I and II, Word Fluency, Animal Naming, Boston Naming, Trail Making Test A and B, Digit Span Backwards, and Digi
Conditions Studied
Interventions
- OTHER Hearing intervention
- OTHER Successful aging/delayed hearing intervention
Study Locations (4)
Maryland
- Johns Hopkins Comstock Center for Public Health Research and Prevention - Hagerstown
Minnesota
- University of Minnesota - Minneapolis
Mississippi
- University of Mississippi Medical Center - Jackson
North Carolina
- Wake Forest University - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 629 participants |
| Start Date | 2023-01-12 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 3 |
What the registry record for NCT05532657 still lists
NCT05532657 is an interventional study that assigns participants to a tested intervention. The registered 629 participants enrollment target is mid-sized for trials with a published cap, below the 2,192-participant average among 262 other Aging trials with a reported enrollment target (71% lower).
The record links to 5 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Hearing intervention is the first listed.
NCT05532657 reports a single indexed study location in Maryland, Minnesota, Mississippi.
Frequently Asked Questions
What is clinical trial NCT05532657 about?
NCT05532657 is a clinical study titled "ACHIEVE Brain Health Follow-Up Study". The ACHIEVE Brain Health Follow-Up Study is a 3-year follow-up to the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) randomized study to determine the long-term effect of hearing intervention vs. successful aging/delayed hearing intervention on rates of cognitive decline and incident mild...
What is the current status of trial NCT05532657?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 629 participants. The study started on 2023-01-12. Estimated completion is 2026-06-30.
What conditions does trial NCT05532657 study?
This clinical trial studies the following conditions: Aging, Mild Cognitive Impairment, Dementia, Cognitive Decline, Hearing Loss.
What interventions are being tested in trial NCT05532657?
The interventions under investigation include: Hearing intervention (OTHER), Successful aging/delayed hearing intervention (OTHER).
Who is sponsoring clinical trial NCT05532657?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05532657 being conducted?
This trial has 4 study locations across Maryland, Minnesota, Mississippi, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05532657's enrollment target sits among peer trials
629 19th of 262 higher than 244 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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