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NCT06689618 · ClinicalTrials.gov registry record · NA
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
A NA study of Aging and Sarcopenia, sponsored by University of Missouri-Columbia.
- Recruiting
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT06689618: Recruiting NA study of Aging and Sarcopenia, sponsored by University of Missouri-Columbia.
NCT06689618 is a NA study of Aging and Sarcopenia that is actively recruiting participants, run by University of Missouri-Columbia. The registered enrollment target is 12 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06689618, a NA study of Aging and Sarcopenia, is actively recruiting participants, sponsored by University of Missouri-Columbia.
- RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age. The investigators will also test whether WB-EMS Exercise will improve measures of physical function. Participants will undergo clinical and electrophysiologic testing before and after the WB-EMS Exercise intervention. The WB-EMS Exercise intervention will be delivered two times per week for four weeks. The hypothesis is that whole-body electrical muscle stimulation combined with physical exercise (WB-EMS Exercise) could bypass the problem of insufficient motoneuronal activation to improve exercise effect in older adults.
Primary Outcome
Decomposition electromyography (dEMG) is a measurement of motor unit activity; a surface electrode will be placed over the vastus lateralis in the thigh and participants will be asked to activate that muscle.
Conditions Studied
Interventions
- DEVICE Exercise
Study Locations (1)
Missouri
- NextGen Precision Health Building, Clinical and Translational Science Unit - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2025-08-18 |
| Est. Completion | 2026-06 |
| Phase | NA |
What NCT06689618 shows while recruiting
NCT06689618 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 1 intervention - of which Exercise is the first listed.
NCT06689618 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT06689618 about?
NCT06689618 is a clinical study titled "Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults". During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age. The investigators will also test whether WB-EMS Exercise will improve measures ...
What is the current status of trial NCT06689618?
This trial is currently recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2025-08-18. Estimated completion is 2026-06.
What conditions does trial NCT06689618 study?
This clinical trial studies the following conditions: Aging, Sarcopenia, Sarcopenia in Elderly.
What interventions are being tested in trial NCT06689618?
The interventions under investigation include: Exercise (DEVICE).
Who is sponsoring clinical trial NCT06689618?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06689618 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aging
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06689618's enrollment target sits among peer trials
12 255th of 262 higher than 7 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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