University of Texas Southwestern Medical Center

742 total trials 582 currently recruiting 122 completed

Trial Pipeline

RECRUITING

Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain

NCT03849963

RECRUITING Early Phase 1

Ketamine in Severe Traumatic Brain Injury

NCT06062628

RECRUITING NA

The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments

NCT07050264

RECRUITING Phase 1

MTOR Inhibitors in Older Adults

NCT06727305

RECRUITING

Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study

NCT07196839

RECRUITING Phase 2

A Polypill for Acute Coronary Syndrome

NCT07032389

RECRUITING NA

Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder

NCT06025734

RECRUITING Phase 2

Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)

NCT07313241

RECRUITING NA

Teen Recovery Through Inspiration, Support, and Empowerment

NCT07170657

RECRUITING Phase 1

Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

NCT07139990

RECRUITING NA

IEEM-Heat and Heart Failure

NCT06961929

RECRUITING Early Phase 1

Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung

NCT06712745

RECRUITING Phase 3

Home-based Cardiac Rehabilitation in Heart Failure

NCT06349941

RECRUITING Phase 1

Periprostatic Neurolysis in Prostate Cancer

NCT07100847

RECRUITING

IEEM- Work:Rest Cycles in Burn Survivors- Humidity

NCT06966336

RECRUITING NA

Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes

NCT06593314

RECRUITING NA

A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections

NCT06940622

RECRUITING

The Unlocking PrEP Study: Integration of Peer Health Navigation Into Comprehensive Re-entry Services

NCT07292792

RECRUITING Phase 2

Escitalopram in Asthma Patients With Frequent Exacerbation

NCT06216535

RECRUITING NA

UTSW NORC Pilot Spinal Cord Injury Dietary Program

NCT06924177

RECRUITING NA

Phosphate Assessment in Chronic Kidney Disease Patients Study

NCT07368946

RECRUITING NA

Leg Heating in Pregnant Women With Obesity

NCT06932250

RECRUITING Phase 1

Study of IOMAB-ACT Followed by CAR-T Cell Therapy for Patients Relapsed or Refractory (Diffuse Large B-cell Lymphoma

NCT06768905

RECRUITING NA

Development and Validation of Virtual Laparoscopic Hiatal Hernia Simulator

NCT06974383

RECRUITING Phase 2

Radiotherapy in Combination With Checkpoint Inhibition for Patients With Metastatic Kidney Cancer

NCT06601296

RECRUITING NA

Recovery Through Inspiration, Support, and Empowerment

NCT07051200

RECRUITING NA

Empowering Perinatal Adolescents Through Writing

NCT06771817

RECRUITING NA

HOTSPOT Study: Implement and Evaluate the PrEP (Pre-exposure Prophylaxis) Implementation Strategy

NCT06919419

RECRUITING Phase 1

Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

NCT06158620

RECRUITING Phase 2

Ligufalimab and Cadonilimab in Advanced Liver Cancers

NCT06789848

RECRUITING Phase 2

Tailored Exercise Training Study Among Adults With HFpEF

NCT07223242

RECRUITING NA

Transcutaneous Auricular Neurostimulation for ICU Patients With Traumatic Brain Injury

NCT06467708

RECRUITING NA

NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study

NCT06593327

RECRUITING

Impact of Extreme Heat on Myocardial Blood Flow and Flow Reserve in Young and Older Adults

NCT06842784

RECRUITING NA

Cardiovascular Responses in Burn Survivors During Exercise

NCT06709781

RECRUITING

ET Stigma Response to Tremor Suppression

NCT07430761

RECRUITING

Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1

NCT06353321

RECRUITING

The Effect of Adiposity on Muscle and Microvascular Function in HFpEF

NCT06930495

RECRUITING Phase 2

Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

NCT06477692

RECRUITING NA

HIV+ Deceased Donor Heart Transplant Study for HIV+ Recipients

NCT06659952

RECRUITING NA

Transcutaneous Auricular Neurostimulation After Lumbar Surgery

NCT06100172

RECRUITING

Optical Coherence Tomography Angiography in Neurological Disease

NCT06797765

RECRUITING Phase 2

Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial

NCT06444269

RECRUITING

Effect of the Stellate Ganglion Block on the Retinal Microcirculation

NCT06797752

RECRUITING Phase 4

Aging, Beta Blockers, and Thermoregulatory Responses

NCT06582680

RECRUITING Phase 2

Ketamine for Methamphetamine Use Disorder

NCT06496750

RECRUITING Phase 1

Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer

NCT06394570

RECRUITING Phase 2

EGCG for Hepatocellular Carcinoma Chemoprevention

NCT06015022

RECRUITING

Sickle Cell Kidney Biorepository

NCT07064174

RECRUITING

Monitoring System for Cranial Orthoses

NCT06425172

RECRUITING

Transference of Established Simulated Skills (TEST) Trial

NCT06572033

RECRUITING NA

Skin Wetting in Burn Survivors

NCT06529757

RECRUITING

Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum Disorder

NCT06398158

RECRUITING

Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy

NCT06814587

RECRUITING NA

Accelerated rTMS for Substance Use Disorder and Depression

NCT06424184

RECRUITING NA

Comprehensive Optimization At-time of Radical Cystectomy Intervention

NCT05714826

RECRUITING NA

Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder

NCT06286930

RECRUITING Phase 2

Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation

NCT06130059

RECRUITING NA

Action Regulation Behavioral

NCT06489483

RECRUITING Phase 3

EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy

NCT05998863

RECRUITING Phase 2

A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)

NCT05576974

RECRUITING NA

Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy

NCT06080503

RECRUITING Phase 2

Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)

NCT06266338

RECRUITING Phase 1

Polypill for Prevention of Cardiomyopathy

NCT06143566

RECRUITING Phase 1

PSMA PET Response Guided SabR in High Risk Pca

NCT06044857

RECRUITING

Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)

NCT06292104

RECRUITING NA

IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine

NCT06218355

RECRUITING Phase 2

Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19

NCT05886816

RECRUITING NA

Targeting Social Function in Anxiety and Eating Disorders

NCT06198023

RECRUITING NA

Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)

NCT05849077

RECRUITING Phase 1

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

NCT05145816

RECRUITING Phase 2

Long Term Efficacy and Safety of Orlistat for Type 1 Hyperlipoproteinemia

NCT05816343

RECRUITING

Artificial Intelligence Prediction Tool in Non-muscle Invasive Bladder Cancer (NMIBC)

NCT05825950

RECRUITING Phase 4

National Liver Cancer Screening Trial

NCT06084234

RECRUITING Phase 2

Sequential Treatment of Cabozantinib for Advanced Renal Cell Carcinoma (RCC)

NCT05931393

RECRUITING Phase 4

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

NCT06003348

RECRUITING

Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression

NCT05966532

RECRUITING NA

CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules

NCT06184152

RECRUITING NA

Diuretic Tuner Clinical Decision Support

NCT04759274

RECRUITING NA

SegwayPD: The Effect of Sensory-augmented Postural Training Using Segway on Motor and Cognitive Function in Individuals With Parkinson's Disease

NCT05982730

RECRUITING

Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury

NCT06480838

RECRUITING

PET/MR for Characterization of Renal Masses (RMs)

NCT06076538

RECRUITING

Cool Prime Comparative Effectiveness Study for Mild HIE

NCT04621279

RECRUITING NA

Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

NCT05723679

RECRUITING

Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial Viability

NCT06047028

RECRUITING NA

Cerebellar Transcranial Direct Current Stimulation (tDCS) in Children With Autism Spectrum Disorder: Raynor Cerebellum Project

NCT05691283

RECRUITING NA

Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation

NCT05917678

RECRUITING NA

Bladder Cancer Screening Trial

NCT05646485

RECRUITING Phase 4

Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation

NCT05489523

RECRUITING Phase 2

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

NCT05446584

RECRUITING Phase 1

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

NCT04796012

RECRUITING NA

Multicomponent Intervention Study- Blood Donors With High Cholesterol

NCT05693701

RECRUITING NA

Heat Waves and the Elderly - Cooling Modalities

NCT05484739

RECRUITING

Outcomes of Focal Ablation for Prostate Cancer

NCT05478694

RECRUITING

Patients With and Without Phonotrauma

NCT05625191

RECRUITING Phase 2

Neoadjuvant Lenvatinib and Pembrolizumab for IVC Tumor Thrombus

NCT05319015

RECRUITING

Laryngeal Cryotherapy for Refractory Neurogenic Cough

NCT05665244

RECRUITING

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

NCT05489549

RECRUITING Phase 3

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

NCT05358535

RECRUITING NA

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

NCT05147909

Phase Distribution

PhaseTrial count
Phase 1 36
Phase 2 105
Phase 3 43
Phase 4 22

What the Pipeline for University of Texas Southwestern Medical Center Shows

According to the ClinicalTrials.gov registry, University of Texas Southwestern Medical Center is linked to 742 US clinical trials across every stage of research activity. Of those, 582 studies are currently recruiting — about 78% of the sponsor's indexed portfolio — and 122 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for University of Texas Southwestern Medical Center reports 65 late-stage studies (Phase 3 and Phase 4 combined) and 141 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for University of Texas Southwestern Medical Center is Hypertension with 9 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial