University of Texas Southwestern Medical Center
Trial Pipeline
Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain
NCT03849963
Ketamine in Severe Traumatic Brain Injury
NCT06062628
The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments
NCT07050264
MTOR Inhibitors in Older Adults
NCT06727305
Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study
NCT07196839
A Polypill for Acute Coronary Syndrome
NCT07032389
Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder
NCT06025734
Phase II Trial of PSA Response-based Androgen Deprivation Therapy and Nodal Coverage for Prostate Cancer Early Salvage Radiotherapy (RANGER)
NCT07313241
Teen Recovery Through Inspiration, Support, and Empowerment
NCT07170657
Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)
NCT07139990
IEEM-Heat and Heart Failure
NCT06961929
Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung
NCT06712745
Home-based Cardiac Rehabilitation in Heart Failure
NCT06349941
Periprostatic Neurolysis in Prostate Cancer
NCT07100847
IEEM- Work:Rest Cycles in Burn Survivors- Humidity
NCT06966336
Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes
NCT06593314
A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections
NCT06940622
The Unlocking PrEP Study: Integration of Peer Health Navigation Into Comprehensive Re-entry Services
NCT07292792
Escitalopram in Asthma Patients With Frequent Exacerbation
NCT06216535
UTSW NORC Pilot Spinal Cord Injury Dietary Program
NCT06924177
Phosphate Assessment in Chronic Kidney Disease Patients Study
NCT07368946
Leg Heating in Pregnant Women With Obesity
NCT06932250
Study of IOMAB-ACT Followed by CAR-T Cell Therapy for Patients Relapsed or Refractory (Diffuse Large B-cell Lymphoma
NCT06768905
Development and Validation of Virtual Laparoscopic Hiatal Hernia Simulator
NCT06974383
Radiotherapy in Combination With Checkpoint Inhibition for Patients With Metastatic Kidney Cancer
NCT06601296
Recovery Through Inspiration, Support, and Empowerment
NCT07051200
Empowering Perinatal Adolescents Through Writing
NCT06771817
HOTSPOT Study: Implement and Evaluate the PrEP (Pre-exposure Prophylaxis) Implementation Strategy
NCT06919419
Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease
NCT06158620
Ligufalimab and Cadonilimab in Advanced Liver Cancers
NCT06789848
Tailored Exercise Training Study Among Adults With HFpEF
NCT07223242
Transcutaneous Auricular Neurostimulation for ICU Patients With Traumatic Brain Injury
NCT06467708
NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study
NCT06593327
Impact of Extreme Heat on Myocardial Blood Flow and Flow Reserve in Young and Older Adults
NCT06842784
Cardiovascular Responses in Burn Survivors During Exercise
NCT06709781
ET Stigma Response to Tremor Suppression
NCT07430761
Non-significant Risk (NSR) Study of [68Ga]-PSMA-11 (Illuccix) as a BgRT BioGuide on RefleXion X1
NCT06353321
The Effect of Adiposity on Muscle and Microvascular Function in HFpEF
NCT06930495
Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy
NCT06477692
HIV+ Deceased Donor Heart Transplant Study for HIV+ Recipients
NCT06659952
Transcutaneous Auricular Neurostimulation After Lumbar Surgery
NCT06100172
Optical Coherence Tomography Angiography in Neurological Disease
NCT06797765
Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
NCT06444269
Effect of the Stellate Ganglion Block on the Retinal Microcirculation
NCT06797752
Aging, Beta Blockers, and Thermoregulatory Responses
NCT06582680
Ketamine for Methamphetamine Use Disorder
NCT06496750
Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer
NCT06394570
EGCG for Hepatocellular Carcinoma Chemoprevention
NCT06015022
Sickle Cell Kidney Biorepository
NCT07064174
Monitoring System for Cranial Orthoses
NCT06425172
Transference of Established Simulated Skills (TEST) Trial
NCT06572033
Skin Wetting in Burn Survivors
NCT06529757
Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum Disorder
NCT06398158
Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy
NCT06814587
Accelerated rTMS for Substance Use Disorder and Depression
NCT06424184
Comprehensive Optimization At-time of Radical Cystectomy Intervention
NCT05714826
Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder
NCT06286930
Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
NCT06130059
Action Regulation Behavioral
NCT06489483
EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy
NCT05998863
A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)
NCT05576974
Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy
NCT06080503
Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)
NCT06266338
Polypill for Prevention of Cardiomyopathy
NCT06143566
PSMA PET Response Guided SabR in High Risk Pca
NCT06044857
Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)
NCT06292104
IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine
NCT06218355
Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19
NCT05886816
Targeting Social Function in Anxiety and Eating Disorders
NCT06198023
Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)
NCT05849077
Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis
NCT05145816
Long Term Efficacy and Safety of Orlistat for Type 1 Hyperlipoproteinemia
NCT05816343
Artificial Intelligence Prediction Tool in Non-muscle Invasive Bladder Cancer (NMIBC)
NCT05825950
National Liver Cancer Screening Trial
NCT06084234
Sequential Treatment of Cabozantinib for Advanced Renal Cell Carcinoma (RCC)
NCT05931393
Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
NCT06003348
Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression
NCT05966532
CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules
NCT06184152
Diuretic Tuner Clinical Decision Support
NCT04759274
SegwayPD: The Effect of Sensory-augmented Postural Training Using Segway on Motor and Cognitive Function in Individuals With Parkinson's Disease
NCT05982730
Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury
NCT06480838
PET/MR for Characterization of Renal Masses (RMs)
NCT06076538
Cool Prime Comparative Effectiveness Study for Mild HIE
NCT04621279
Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF
NCT05723679
Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial Viability
NCT06047028
Cerebellar Transcranial Direct Current Stimulation (tDCS) in Children With Autism Spectrum Disorder: Raynor Cerebellum Project
NCT05691283
Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation
NCT05917678
Bladder Cancer Screening Trial
NCT05646485
Safety, Efficacy, and Pharmacokinetics of Tafamidis in Patients With Transthyretin-mediated Amyloidosis Post Orthotopic Heart Transplantation
NCT05489523
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
NCT05446584
VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors
NCT04796012
Multicomponent Intervention Study- Blood Donors With High Cholesterol
NCT05693701
Heat Waves and the Elderly - Cooling Modalities
NCT05484739
Outcomes of Focal Ablation for Prostate Cancer
NCT05478694
Patients With and Without Phonotrauma
NCT05625191
Neoadjuvant Lenvatinib and Pembrolizumab for IVC Tumor Thrombus
NCT05319015
Laryngeal Cryotherapy for Refractory Neurogenic Cough
NCT05665244
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers
NCT05489549
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
NCT05358535
Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity
NCT05147909
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 36 |
| Phase 2 | 105 |
| Phase 3 | 43 |
| Phase 4 | 22 |
Therapeutic Areas
What the Pipeline for University of Texas Southwestern Medical Center Shows
According to the ClinicalTrials.gov registry, University of Texas Southwestern Medical Center is linked to 742 US clinical trials across every stage of research activity. Of those, 582 studies are currently recruiting — about 78% of the sponsor's indexed portfolio — and 122 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of Texas Southwestern Medical Center reports 65 late-stage studies (Phase 3 and Phase 4 combined) and 141 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of Texas Southwestern Medical Center is Hypertension with 9 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.