Medical Information Only. Consult your healthcare provider before enrolling in any clinical trial.
Colorado: below-average open trial sites
1,650 of 5,273 in-state trials are recruiting (31%); below the 37% national average by 6 percentage points.
According to ClinicalTrials.gov-derived indexes, Colorado sits in the upper quartile of US states by in-state trial count (#12 of 52 states by registered in-state trial count).
Colorado: 5,273 US clinical trials with in-state sites, 1,650 recruiting.
Colorado has 5,273 registered US clinical trials with a study site in-state, 1,650 of them currently recruiting (below the 37% national average by 6 percentage points). 1,536 of these trials are in Phase 3 (late-stage) and 1,205 in Phase 2. The most frequently studied condition in Colorado is HIV Infections, with 107 linked trials.
Upper-quartile research density
Colorado sits in the upper quartile by in-state trial count. Open share is below the 37% national average by 6 percentage points - denser than most states, still short of the top-decile research hubs.
Below-average open enrollment
Colorado still shows 1,650 recruiting of 5,273 in-state trials (31% open), but below the 37% national average by 6 percentage points, so archived statuses weigh heavier than the national baseline.
- 31%
- open (below national share)
- 1,650
- still recruiting despite cool share
- 1,205
- Phase 2 rows in this footprint
- 107
- top: HIV Infections
Recruiting share is below the 37% national average by 6 percentage points. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
Colorado vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
5,273 Top 23% more indexed trials than 77% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for Colorado on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Colorado open-enrollment share sits below the national baseline.
1,650 of 5,273 in-state trials (31.3%) are recruiting, against 37% nationally (-5.7 percentage points). Counts include every study with at least one recorded site in the state.
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Colorado trial sites spread across 8 city hubs.
Aurora lists 2,514 of 5,273 in-state trials (47.7%) across 710 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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HIV Infections is the most-studied condition in Colorado.
107 of 5,273 in-state trials (2%) list HIV Infections. That is a local concentration figure, not a national disease ranking.
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One sponsor accounts for a large share of Colorado trials.
University of Colorado, Denver appears on 525 of 5,273 in-state trials (10%). Sponsor identity is as filed on ClinicalTrials.gov.
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2,339 Colorado trials carry a completed status.
2,339 of 5,273 (44.4%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 2,339 |
| Recruiting | 1,650 |
| Active | 1,284 |
By Phase
| Phase | Trial count |
|---|---|
| Phase 3 | 1,536 |
| Phase 2 | 1,205 |
| NA | 884 |
| Phase 1 | 726 |
| Phase 4 | 215 |
| Early Phase 1 | 22 |
Top Conditions
Top Sponsors
Where trials run in Colorado
Aurora carries 2,514 of Colorado's 5,273 indexed trials (48%) across 710 named sites, ahead of Denver at 1,712. 8 cities clear five listed trials, together naming 2,068 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Aurora | 2,514 | 710 |
| Denver | 1,712 | 660 |
| Colorado Springs | 512 | 256 |
| Englewood | 250 | 123 |
| Fort Collins | 188 | 99 |
| Boulder | 182 | 77 |
| Lakewood | 162 | 78 |
| Littleton | 132 | 65 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Volume high
Colorado indexes 5,273 in-state trials (p78 by registry volume among 52 states with sites).
Colorado: in-state trial volume sits in the high tercile
Sites spread across 8 cities with five or more listed trials, led by Aurora (2,514, 48% of the state total) and Denver (1,712), together naming 2,068 distinct research locations.
Phase mix: 1,536 Phase 3 vs 1,205 Phase 2 (balanced across stages).
Top condition: HIV Infections (107 trials); top sponsor University of Colorado, Denver (525).
high-volume · mid-open figures (5,273 trials · 31% open) describe registry geography under the volume high read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near Colorado on in-state trial volume
Cross-state peers under the volume high read (high-volume · mid-open), not the same-state browse list.
Similar high-volume hubs (± open share)
- Arizona · 5,607 trials · 30% recruiting
- North Carolina · 5,625 trials · 33% recruiting
- Michigan · 4,790 trials · 34% recruiting
- Minnesota · 4,506 trials · 36% recruiting
- Alabama · 4,168 trials · 29% recruiting
Similar mid-open peers (± trial volume)
- District of Columbia · 31% recruiting · 2,316 trials
- Vermont · 31% recruiting · 191 trials
- South Dakota · 31% recruiting · 273 trials
- Georgia · 32% recruiting · 5,195 trials
- Kentucky · 32% recruiting · 2,183 trials