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RECRUITING Phase 2

A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder

NCT06817356 · View on ClinicalTrials.gov ↗

Study Summary

The objective of this proof-of-concept study to evaluate mazdutide in participants with alcohol use disorder (AUD). For any individual participant, the maximum duration of study participation is approximately 36 weeks, including screening and posttreatment follow-up.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Mazdutide

Study Locations (20)

Florida

  • Research Centers of America ( Hollywood ) — Hollywood
  • K2 Medical Research - Maitland — Maitland
  • K2 Medical Research — Maitland
  • Clinical Neuroscience Solutions Inc — Orlando
  • Clinical Neuroscience Solutions, Inc. — Orlando
  • K2 Medical Research - Tampa — Tampa

California

  • Ark Clinical Research - Fountain Valley — Fountain Valley
  • Synergy San Diego — Lemon Grove
  • Headlands Research-Artemis San Diego — San Diego

Arkansas

  • Woodland International Research Group — Little Rock
  • Woodland Resarch Northwest/ERG — Rogers

Massachusetts

  • Adams Clinical — Watertown
  • Vitalix Clinical — Worcester

New York

  • Richmond Behavioral Associates — Staten Island
  • Ichor Research — Syracuse

Arizona

  • Headlands Research - Scottsdale — Scottsdale

Georgia

  • CenExel iResearch, LLC (CenExel iRA) — Decatur

Louisiana

  • DelRicht Research — Mandeville

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2025-02-06
Est. Completion 2026-08
Phase Phase 2

Sponsor

Eli Lilly and Company

704 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06817356

The ClinicalTrials.gov registry entry for NCT06817356 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06817356 reports 20 study locations spanning 10 distinct geographic areas — top geographies include Florida, California, Arkansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06817356 about?

NCT06817356 is a clinical study titled "A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder". The objective of this proof-of-concept study to evaluate mazdutide in participants with alcohol use disorder (AUD). For any individual participant, the maximum duration of study participation is approximately 36 weeks, including screening and posttreatment follow-up.

What is the current status of trial NCT06817356?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 300 participants. The study started on 2025-02-06. Estimated completion is 2026-08.

What conditions does trial NCT06817356 study?

This clinical trial studies the following conditions: Alcohol Use Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06817356?

The interventions under investigation include: Placebo (DRUG), Mazdutide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06817356?

This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06817356 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial