Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06945419 · ClinicalTrials.gov registry record · Phase 1
A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes
A Phase 1 study of Healthy and Obesity, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 201
- Enrollment target
- 5
- Study locations
NCT06945419 is a Phase 1 study of Healthy and Obesity that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 201 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (69% lower). The trial reports 5 study locations across 3 states.
The verdict
NCT06945419, a Phase 1 study of Healthy and Obesity, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 201 participants
- Enrollment target
- 5
- Study locations
Study Summary
The main purpose of this study is to evaluate the safety, tolerability of LY4086940 and how it is processed in the body. Participation in Part A of the study will last about 10 weeks and may include up to 6 visits. Participation in Parts B, C, D will last approximately 15 weeks and may include up to 9 visits. Participation in Part E will last approximately 7 weeks and may include up to 12 visits.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG LY4086940
Study Locations (5)
Florida
- Fortrea Clinical Research Unit - Daytona Beach
- Clinical Pharmacology of Miami - Miami
Texas
- Fortrea Clinical Research Unit - Dallas
- Endeavor Clinical Trials - San Antonio
Other
- Lilly Centre for Clinical Pharmacology - Singapore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 201 participants |
| Start Date | 2025-04-23 |
| Est. Completion | 2026-04 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06945419
The ClinicalTrials.gov registry entry for NCT06945419 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 201 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (69% lower). The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06945419 reports 5 study locations spanning 3 distinct geographic areas - top geographies include Florida, Texas, Other.
Frequently Asked Questions
What is clinical trial NCT06945419 about?
NCT06945419 is a clinical study titled "A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes". The main purpose of this study is to evaluate the safety, tolerability of LY4086940 and how it is processed in the body. Participation in Part A of the study will last about 10 weeks and may include up to 6 visits. Participation in Parts B, C, D will last approximately 15 weeks and may include up t...
What is the current status of trial NCT06945419?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 201 participants. The study started on 2025-04-23. Estimated completion is 2026-04.
What conditions does trial NCT06945419 study?
This clinical trial studies the following conditions: Healthy, Obesity, Type 2 Diabetes, Overweight.
What interventions are being tested in trial NCT06945419?
The interventions under investigation include: Placebo (DRUG), LY4086940 (DRUG).
Who is sponsoring clinical trial NCT06945419?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06945419 being conducted?
This trial has 5 study locations across Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
RECRUITING · Phase 1
-
A Study of LY3867070 in Healthy Participants
RECRUITING · Phase 1
-
A Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of AZD1613 in Healthy Participants.
RECRUITING · Phase 1
-
Evaluate the Pharmacokinetics, Safety, and Tolerability of NSHO-101 in Healthy Participants
RECRUITING · Phase 1
-
Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging
RECRUITING · Phase 1
-
A Study of V118E in Healthy Participants (V118E-003)
RECRUITING · Phase 1
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.