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NCT06672939 · ClinicalTrials.gov registry record · Phase 3
A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities
A Phase 3 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 125
- Enrollment target
- 20
- Study locations
NCT06672939: Recruiting Phase 3 study of Obesity and Overweight, sponsored by Eli Lilly and Company.
NCT06672939 is a Phase 3 study of Obesity and Overweight that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 125 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (85% lower). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06672939, a Phase 3 study of Obesity and Overweight, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 125 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main purpose of this study, performed under Master Protocol J4M-MC-PWMP, is to evaluate the efficacy, safety, and pharmacokinetics of orforglipron once daily oral versus Placebo in adolescent participants with obesity, or overweight with related comorbidities. Participation in the study will last about 18 months.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Orforglipron
Study Locations (20)
Other
- Shamir Medical Center - Beer Jacob
- Shaare Zedek Medical Center - Jerusalem
- Sheba Medical Center - Ramat Gan
- Azienda Ospedaliero Universitaria Meyer - Florence
- Azienda Ospedaliero Universitaria Maggiore della Carità - Novara
Texas
- Dynamed Clinical Research, LP d/b/a DM Clinical Research - Houston
- La Providence Pediatrics Clinic - Chemidox Clinical Trials - Houston
- Martin Diagnostic Clinic - Tomball
Connecticut
- Yale School of Medicine - Yale Diabetes Center (YDC)) Trials - New Haven
- Stamford Therapeutics Consortium - Stamford
California
- Carey Chronis MD Pediatric, Infant and Adolescent Medicine - Ventura
Georgia
- Children's Healthcare of Atlanta - Center for Advanced Pediatrics - Atlanta
Illinois
- Ann & Robert H. Lurie Children's Hospital of Chicago - Chicago
Louisiana
- Velocity Clinical Research - Lafayette
Mississippi
- MedPharmics, LLC - Gulfport
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 125 participants |
| Start Date | 2024-11-18 |
| Est. Completion | 2027-03 |
| Phase | Phase 3 |
What NCT06672939 shows while recruiting
NCT06672939 is an interventional study that assigns participants to a tested intervention. The registered 125 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (85% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06672939 names 20 study sites across 13 states, led by Other, Texas, Connecticut.
Frequently Asked Questions
What is clinical trial NCT06672939 about?
NCT06672939 is a clinical study titled "A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities". The main purpose of this study, performed under Master Protocol J4M-MC-PWMP, is to evaluate the efficacy, safety, and pharmacokinetics of orforglipron once daily oral versus Placebo in adolescent participants with obesity, or overweight with related comorbidities. Participation in the study will las...
What is the current status of trial NCT06672939?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 125 participants. The study started on 2024-11-18. Estimated completion is 2027-03.
What conditions does trial NCT06672939 study?
This clinical trial studies the following conditions: Obesity, Overweight.
What interventions are being tested in trial NCT06672939?
The interventions under investigation include: Placebo (DRUG), Orforglipron (DRUG).
Who is sponsoring clinical trial NCT06672939?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06672939 being conducted?
This trial has 20 study locations across California, Connecticut, Georgia, Illinois, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06672939's enrollment target sits among peer trials
125 426th of 1053 higher than 627 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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