Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 3

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

NCT07202884 · View on ClinicalTrials.gov ↗

Study Summary

The GZPS master protocol will support two independent studies, J2A-MC-GZS1 and J2A-MC-GZS2. Each study will see how well and safely orforglipron works in adult female participants with stress urinary incontinence (SUI) who have obesity or overweight. SUI is leaking urine during movement or activity such as coughing or exercising. Participation in the study will last about 58 weeks from screening to safety follow-up.

Interventions

  • DRUG Placebo
  • DRUG Orforglipron

Study Locations (20)

Florida

  • AMR Clinical — Fort Myers
  • Altus Research — Lake Worth
  • New Age Medical Research Corporation — Miami
  • Emerald Coast OBGYN Clinical Research — Panama City

California

  • Matrix Clinical Research — Los Angeles
  • Alarcon Urology Center — Montebello
  • Prestige Medical Group — Tustin

Alabama

  • University of Alabama -The Kirklin Clinic — Birmingham
  • AMR Clinical — Mobile

Pennsylvania

  • OB/GYN Associates of Erie — Erie
  • Clinical Research of Philadelphia — Philadelphia

Texas

  • Next Level Urgent Care — Houston
  • Innovative Medical Research of Texas — Houston

Virginia

  • Health Research of Hampton Roads, Inc. — Newport News
  • Urology of Virginia — Virginia Beach

Arizona

  • Urologic Surgeons of Arizona — Mesa

Colorado

  • Colorado Clinical Research — Lakewood

Trial Details

FieldValue
Enrollment Target 1,000 participants
Start Date 2025-09-30
Est. Completion 2028-03
Phase Phase 3

Sponsor

Eli Lilly and Company

704 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07202884

The ClinicalTrials.gov registry entry for NCT07202884 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Urinary Incontinence,Stress appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07202884 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Florida, California, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07202884 about?

NCT07202884 is a clinical study titled "A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight". The GZPS master protocol will support two independent studies, J2A-MC-GZS1 and J2A-MC-GZS2. Each study will see how well and safely orforglipron works in adult female participants with stress urinary incontinence (SUI) who have obesity or overweight. SUI is leaking urine during movement or activity ...

What is the current status of trial NCT07202884?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,000 participants. The study started on 2025-09-30. Estimated completion is 2028-03.

What conditions does trial NCT07202884 study?

This clinical trial studies the following conditions: Urinary Incontinence,Stress. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07202884?

The interventions under investigation include: Placebo (DRUG), Orforglipron (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07202884?

This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07202884 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial