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RECRUITING Phase 2

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

NCT07219173 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma. Study participation will last approximately 65 weeks, including screening, treatment, and follow-up periods.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Brenipatide

Study Locations (20)

Florida

  • AMR Clinical — Doral
  • Renstar Medical Research — Ocala
  • Avanza Medical Research Center — Pensacola
  • USF Health — Tampa

California

  • NewportNativeMD, Inc. — Newport Beach
  • California Medical Research Associates — Northridge
  • Peninsula Research Associates — Rolling Hills Estates

Other

  • Consultorios Médicos, Organización del Buen Ayre S.R.L. — Buenos Aires
  • Centro de Investigaciones Metabólicas (CINME) — Buenos Aires
  • Fundación Respirar — Buenos Aires

Pennsylvania

  • University of Pittsburgh Medical Center — Pittsburgh
  • Allergy and Clinical Immunology Associates — Pittsburgh

Arizona

  • AMR Clinical — Tempe

Colorado

  • Asthma & Allergy Associates - Colorado Springs — Colorado Springs

Illinois

  • Axis Clinical Trials - Westchester — Westchester

Kentucky

  • Allergy & Asthma Specialists, P.S.C. — Owensboro

Trial Details

FieldValue
Enrollment Target 531 participants
Start Date 2025-10-22
Est. Completion 2028-06
Phase Phase 2

Sponsor

Eli Lilly and Company

704 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07219173

The ClinicalTrials.gov registry entry for NCT07219173 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 531 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Asthma appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07219173 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, California, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07219173 about?

NCT07219173 is a clinical study titled "A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma". The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma. Study participation will last approximately 65 weeks, including screening, treatment, and follow-up periods.

What is the current status of trial NCT07219173?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 531 participants. The study started on 2025-10-22. Estimated completion is 2028-06.

What conditions does trial NCT07219173 study?

This clinical trial studies the following conditions: Asthma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07219173?

The interventions under investigation include: Placebo (DRUG), Brenipatide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07219173?

This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07219173 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial