Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06964776 · ClinicalTrials.gov registry record · Phase 1

A Study of LY4268989 (MORF-057) in Healthy Participants

A Phase 1 study of Healthy, sponsored by Eli Lilly and Company.

Recruiting
Registry status
Phase 1
Development phase
144
Enrollment target
1
Study location

NCT06964776: Recruiting Phase 1 study of Healthy, sponsored by Eli Lilly and Company.

NCT06964776 is a Phase 1 study of Healthy that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 144 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06964776, a Phase 1 study of Healthy, is actively recruiting participants, sponsored by Eli Lilly and Company.

RECRUITING
Registry status
Phase 1
Development phase
144 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to measure the body's absorption and processing of the study drug, the study drug's effect on the body, safety, and tolerability with LY4268989 (MORF-57) in healthy participants, including Japanese and Chinese participants

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Midazolam
  • DRUG LY4268989

Study Locations (1)

California

  • CenExel ACT - Anaheim

Trial Details

FieldValue
Enrollment Target 144 participants
Start Date 2025-05-01
Est. Completion 2026-02
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What NCT06964776 shows while recruiting

NCT06964776 is an interventional study that assigns participants to a tested intervention. The registered 144 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (78% lower).

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT06964776 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06964776 about?

NCT06964776 is a clinical study titled "A Study of LY4268989 (MORF-057) in Healthy Participants". The purpose of this study is to measure the body's absorption and processing of the study drug, the study drug's effect on the body, safety, and tolerability with LY4268989 (MORF-57) in healthy participants, including Japanese and Chinese participants

What is the current status of trial NCT06964776?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 144 participants. The study started on 2025-05-01. Estimated completion is 2026-02.

What conditions does trial NCT06964776 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT06964776?

The interventions under investigation include: Placebo (DRUG), Midazolam (DRUG), LY4268989 (DRUG).

Who is sponsoring clinical trial NCT06964776?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06964776 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06964776's enrollment target sits among peer trials

144 161st of 1090 higher than 929 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01861106 · 144 participants · Phase 2

    Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

  • NCT03482245 · 144 participants · NA

    The Role of Circadian Clock Proteins in Innate and Adaptive Immunity

  • NCT03504683 · 144 participants · NA

    MEAL TIMING Study: Effect of Time-Restricted Feeding on 24-hour Glycemic Control, Blood Pressure, and Cardiovascular Disease Risk Factors in Adults With Prediabetes

  • NCT03905603 · 144 participants · Early Phase 1

    Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06964776, the US trial registry maintained by the National Library of Medicine. NCT06964776 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.