Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes
NCT06972472 · View on ClinicalTrials.gov ↗
Study Summary
The main purpose of this study is to see how orforglipron, compared with placebo, helps improve glycemic control in participants with obesity or with overweight and type 2 diabetes. This trial is part of the master protocol study J2A-MC-GZPO. Participation in the study will last about 18 months.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Orforglipron
Study Locations (20)
Florida
- Accel Research Sites - DeLand Clinical Research Unit — DeLand
- Innovation Medical Research Center - Fort Lauderdale — Fort Lauderdale
- Indago Research & Health Center, Inc — Hialeah
- Encore Medical Research — Hollywood
- West Orange Endocrinology P.A. — Ocoee
- Care Access - Tampa — Tampa
Georgia
- Accel Research Sites - NeuroStudies Clinical Research Unit — Decatur
- Care Access - Decatur — Decatur
- Javara - Privia Medical Group Georgia - Savannah — Savannah
- North Georgia Clinical Research — Woodstock
California
- Norcal Endocrinology & Internal Medicine — San Ramon
- Southern California Clinical Research — Santa Ana
- Care Access - Thousand Oaks — Thousand Oaks
Arizona
- Clinical Research Institute of Arizona (CRI) - Sun City West — Sun City West
- Novak Clinical Research - Tucson - North La Cholla Boulevard — Tucson
Maryland
- Endocrine and Metabolic Consultants — Rockville
- Javara - Privia Medical Group - Silver Spring — Silver Spring
Idaho
- Solaris Clinical Research — Meridian
Louisiana
- Care Access - New Iberia — New Iberia
Montana
- Boeson Research MSO — Missoula
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2025-05-19 |
| Est. Completion | 2027-08 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06972472
The ClinicalTrials.gov registry entry for NCT06972472 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06972472 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Florida, Georgia, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06972472 about?
NCT06972472 is a clinical study titled "A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Type 2 Diabetes". The main purpose of this study is to see how orforglipron, compared with placebo, helps improve glycemic control in participants with obesity or with overweight and type 2 diabetes. This trial is part of the master protocol study J2A-MC-GZPO. Participation in the study will last about 18 months.
What is the current status of trial NCT06972472?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 600 participants. The study started on 2025-05-19. Estimated completion is 2027-08.
What conditions does trial NCT06972472 study?
This clinical trial studies the following conditions: Obesity, Type 2 Diabetes, Overweight. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06972472?
The interventions under investigation include: Placebo (DRUG), Orforglipron (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06972472?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06972472 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Georgia, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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