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NCT07219953 · ClinicalTrials.gov registry record · Phase 3

A Study of Brenipatide in Participants With Alcohol Use Disorder

A Phase 3 study of Alcohol Use Disorder, sponsored by Eli Lilly and Company.

Recruiting
Registry status
Phase 3
Development phase
1,100
Enrollment target
20
Study locations

NCT07219953 is a Phase 3 study of Alcohol Use Disorder that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 1,100 participants, above the 322-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (242% higher). The trial reports 20 study locations across 8 states.

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The verdict

NCT07219953, a Phase 3 study of Alcohol Use Disorder, is actively recruiting participants, sponsored by Eli Lilly and Company.

RECRUITING
Registry status
Phase 3
Development phase
1,100 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with Alcohol Use Disorder (AUD) and hazardous alcohol use. Participation in this study will last approximately 56 weeks.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG LY3537031

Study Locations (20)

Florida

  • Accel Research Sites - Lakeland Clinical Research Unit - Lakeland
  • Innovative Clinical Research - Lauderhill
  • K2 Medical Research - Maitland - Maitland
  • K2 Medical Research ORLANDO - Maitland
  • Life Arc Research Centers - Miami - Miami
  • Wellness Research Center - Miami
  • Life Medical Research Group Corp - Miami Gardens
  • Charter Research - Orlando - Orlando
  • K2 Medical Research - Tampa - Tampa

California

  • UCLA Clinical & Translational Research Center (CTRC) - Los Angeles
  • Artemis Institute for Clinical Research - Riverside
  • Artemis Institute for Clinical Research - San Diego
  • UCSF Weill Institute for Neurosciences - Substance Use Disorders Clinic - Mission Bay - San Francisco

Maryland

  • Maryland Treatment Centers - Mountain Manor Treatment Center - Baltimore
  • Maryland Treatment Centers - Avery Road Treatment Center - Rockville

Alabama

  • Parkway Medical Center - Birmingham

Arizona

  • Headlands Research - Scottsdale - Scottsdale

Arkansas

  • Woodland International Research Group - Little Rock

Illinois

  • Re:Cognition Health - Chicago - Chicago

Massachusetts

  • Adams Clinical Boston - Boston

Trial Details

FieldValue
Enrollment Target 1,100 participants
Start Date 2025-10-16
Est. Completion 2028-04
Phase Phase 3

Sponsor

Eli Lilly and Company

1,341 total trials

What the Registry Record Tells You About NCT07219953

The ClinicalTrials.gov registry entry for NCT07219953 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 1,100 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 322-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (242% higher). The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07219953 reports 20 study locations spanning 8 distinct geographic areas - top geographies include Florida, California, Maryland.

Frequently Asked Questions

What is clinical trial NCT07219953 about?

NCT07219953 is a clinical study titled "A Study of Brenipatide in Participants With Alcohol Use Disorder". The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with Alcohol Use Disorder (AUD) and hazardous alcohol use. Participation in this study will last approximately 56 weeks.

What is the current status of trial NCT07219953?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,100 participants. The study started on 2025-10-16. Estimated completion is 2028-04.

What conditions does trial NCT07219953 study?

This clinical trial studies the following conditions: Alcohol Use Disorder.

What interventions are being tested in trial NCT07219953?

The interventions under investigation include: Placebo (DRUG), LY3537031 (DRUG).

Who is sponsoring clinical trial NCT07219953?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07219953 being conducted?

This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.