Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
NCT07215559 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to investigate weight reduction with macupatide and eloralintide, alone or in combination, in adult participants with obesity or overweight and with type 2 diabetes. Participation in the study will last about 48 weeks.
Conditions Studied
Interventions
- DRUG Eloralintide
- DRUG Macupatide
- DRUG Macupatide Placebo
- DRUG Eloralintide Placebo
Study Locations (20)
Texas
- Mercy Family Clinic — Dallas
- Velocity Clinical Research, Dallas — Dallas
- PlanIt Research, PLLC — Houston
- Aavon Clinical Trials — Richmond
- Consano Clinical Research, LLC — Shavano Park
- Texas Valley Clinical Research — Weslaco
Georgia
- SKY Clinical Research Network Group-Brown — Atlanta
- Teak Research Consults — Lawrenceville
- AGILE Clinical Research Trials, LLC — Sandy Springs
- Pivotal Research Solutions — Stonecrest
- Rophe Adult and Pediatric Medicine/SKYCRNG — Union City
Arizona
- Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC — Gilbert
- Synexus Clinical Research US, Inc. — Phoenix
- Pima Heart — Tucson
Virginia
- Eastern Virginia Medical School (EVMS) Medical Group — Norfolk
- Clinical Research Partners, LLC — Richmond
Nevada
- Vector Clinical Trials — Las Vegas
New Jersey
- Premier Research — Trenton
Utah
- Kalo Clinical Research — West Valley City
Washington
- Northwest Clinical Research Center — Bellevue
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-10-16 |
| Est. Completion | 2027-05 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07215559
The ClinicalTrials.gov registry entry for NCT07215559 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 4 interventions — of which Eloralintide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07215559 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Texas, Georgia, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07215559 about?
NCT07215559 is a clinical study titled "A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes". The purpose of this study is to investigate weight reduction with macupatide and eloralintide, alone or in combination, in adult participants with obesity or overweight and with type 2 diabetes. Participation in the study will last about 48 weeks.
What is the current status of trial NCT07215559?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2025-10-16. Estimated completion is 2027-05.
What conditions does trial NCT07215559 study?
This clinical trial studies the following conditions: Obesity, Diabetes Mellitus, Type 2, Overweight. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07215559?
The interventions under investigation include: Eloralintide (DRUG), Macupatide (DRUG), Macupatide Placebo (DRUG), Eloralintide Placebo (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07215559?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07215559 being conducted?
This trial has 20 study locations across Arizona, Georgia, Nevada, New Jersey, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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