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NCT07215559 · ClinicalTrials.gov registry record · Phase 2
A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes
A Phase 2 study of Obesity and Diabetes Mellitus, Type 2, sponsored by Eli Lilly and Company.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
- 20
- Study locations
NCT07215559: Recruiting Phase 2 study of Obesity and Diabetes Mellitus, Type 2, sponsored by Eli Lilly and Company.
NCT07215559 is a Phase 2 study of Obesity and Diabetes Mellitus, Type 2 that is actively recruiting participants, run by Eli Lilly and Company. The registered enrollment target is 200 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (76% lower). The trial reports 20 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07215559, a Phase 2 study of Obesity and Diabetes Mellitus, Type 2, is actively recruiting participants, sponsored by Eli Lilly and Company.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to investigate weight reduction with macupatide and eloralintide, alone or in combination, in adult participants with obesity or overweight and with type 2 diabetes. Participation in the study will last about 48 weeks.
Conditions Studied
Interventions
- DRUG Eloralintide
- DRUG Macupatide
- DRUG Macupatide Placebo
- DRUG Eloralintide Placebo
Study Locations (20)
Texas
- Mercy Family Clinic - Dallas
- Velocity Clinical Research, Dallas - Dallas
- PlanIt Research, PLLC - Houston
- Aavon Clinical Trials - Richmond
- Consano Clinical Research, LLC - Shavano Park
- Texas Valley Clinical Research - Weslaco
Georgia
- SKY Clinical Research Network Group-Brown - Atlanta
- Teak Research Consults - Lawrenceville
- AGILE Clinical Research Trials, LLC - Sandy Springs
- Pivotal Research Solutions - Stonecrest
- Rophe Adult and Pediatric Medicine/SKYCRNG - Union City
Arizona
- Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC - Gilbert
- Synexus Clinical Research US, Inc. - Phoenix
- Pima Heart - Tucson
Virginia
- Eastern Virginia Medical School (EVMS) Medical Group - Norfolk
- Clinical Research Partners, LLC - Richmond
Nevada
- Vector Clinical Trials - Las Vegas
New Jersey
- Premier Research - Trenton
Utah
- Kalo Clinical Research - West Valley City
Washington
- Northwest Clinical Research Center - Bellevue
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-10-16 |
| Est. Completion | 2027-05 |
| Phase | Phase 2 |
What NCT07215559 shows while recruiting
NCT07215559 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (76% lower).
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 4 interventions - of which Eloralintide is the first listed.
NCT07215559 names 20 study sites across 8 states, led by Texas, Georgia, Arizona.
Frequently Asked Questions
What is clinical trial NCT07215559 about?
NCT07215559 is a clinical study titled "A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes". The purpose of this study is to investigate weight reduction with macupatide and eloralintide, alone or in combination, in adult participants with obesity or overweight and with type 2 diabetes. Participation in the study will last about 48 weeks.
What is the current status of trial NCT07215559?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2025-10-16. Estimated completion is 2027-05.
What conditions does trial NCT07215559 study?
This clinical trial studies the following conditions: Obesity, Diabetes Mellitus, Type 2, Overweight.
What interventions are being tested in trial NCT07215559?
The interventions under investigation include: Eloralintide (DRUG), Macupatide (DRUG), Macupatide Placebo (DRUG), Eloralintide Placebo (DRUG).
Who is sponsoring clinical trial NCT07215559?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07215559 being conducted?
This trial has 20 study locations across Arizona, Georgia, Nevada, New Jersey, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07215559's enrollment target sits among peer trials
200 315th of 1053 higher than 732 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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