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Post Traumatic Stress Disorder clinical trials
71 of 146 indexed Post Traumatic Stress Disorder trials are currently recruiting.
146 US clinical trials · 71 currently recruiting
Post Traumatic Stress Disorder is the subject of 146 registered US clinical trials on ClinicalTrials.gov, 71 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 30 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 19 of these trials.
The research picture
Post Traumatic Stress Disorder has 146 registered US clinical trials, 71 of them open to new participants right now, about 49% of the total.
- 71
- recruiting participants now
- 49%
- of trials open to enrollment
- 13
- in Phase 3–4 (later-stage)
- 19
- top sponsor: VA Office of Research and Development
Active & Recent Trials
146 total, page 2 of 3
Disrupting Fear-based Memory Consolidation
Emory University
NCT05560113
TMS-fNIRS Personalized Dosing
Florida State University
NCT05916417
Pimavanserin for Insomnia in Veterans With PTSD
VA Office of Research and Development
NCT05441280
Mechanisms Underlying Efficacy of Prolonged Exposure
Massachusetts General Hospital
NCT05788302
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Yale University
NCT05915013
Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder
Stanford University
NCT06577636
Exploring Virtual Reality Adventure Training Exergaming
The University of Texas at Arlington
NCT05563805
Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms
Oui Therapeutics
NCT07316088
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
Stephen Robert Marder
NCT05790239
Advanced Wireless Augmented Reality-Enhanced Exposure Therapy for Posttraumatic Stress Disorder
Wayne State University
NCT06740487
Targeting the Default Mode Network: A TMS-fMRI Study
Allyson Rosen
NCT05646732
Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI
The University of Texas Health Science Center at San Antonio
NCT07351305
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Yale University
NCT05786066
Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD
Montefiore Medical Center
NCT05929911
Innovative Multimodal and Attention Training to Improve Emotion Communication in Veterans With TBI and PTSD
VA Office of Research and Development
NCT05478759
eTMS for Veterans and First Responders With PTSD
Virginia Polytechnic Institute and State University
NCT06294106
Brief Treatment for Trauma Nightmares in Trauma-exposed Adults With Bipolar Disorder
University of Tul
NCT02242110
MDMA-assisted Massed Prolonged Exposure for PTSD
Healing Breakthrough
NCT06117306
An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder
Donald Jeffrey Newport
NCT05254405
MDMA for AUD/PTSD Comorbidity
Carolina L Haass-Koffler
NCT05943665
Responsive Neurostimulation for Post-Traumatic Stress Disorder
VA Greater Los Angeles Healthcare System
NCT04152993
Stellate Ganglion Block for PTSD
VA Office of Research and Development
NCT05169190
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Massachusetts General Hospital
NCT01075672
Efficacy of Virtual Warrior Renew Therapy for Veterans Who Experienced Military Sexual Trauma
Seattle Institute for Biomedical and Clinical Research
NCT05776719
Testing the Effectiveness of a Therapist-Assisted Self-Management Program for Veterans Who Finished PTSD Therapy
VA Office of Research and Development
NCT05797441
Web-administered STAIR for Patients on Behavioral Health Waitlists
Boston Medical Center
NCT06431022
MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence
Michigan State University
NCT05106361
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
Wayne State University
NCT05474534
TMS for PTSD and Blood Pressure
Lifespan
NCT05512143
A Study of Psilocybin for PTSD
Johns Hopkins University
NCT06407635
An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers
Wayne State University
NCT06054412
Targeted Plasticity Therapy for Posttraumatic Stress Disorder
Baylor Research Institute
NCT04064762
Rare Group Problem Management Plus
Children's National Research Institute
NCT06548022
Pilot rTMS for AUD+mTBI
VA Office of Research and Development
NCT03995173
Long Term Health Outcomes of Women Veterans' Service During the Vietnam Era
VA Office of Research and Development
NCT00958061
National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database
Hugo W. Moser Research Institute at Kennedy Krieger
NCT01591694
Evaluating the Effects of Stress in Pregnancy
Emory University
NCT00525226
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
University of New Hampshire
NCT03488927
Remotely Resolving Psychological Stress (Remote RePS)
University of California, San Francisco
NCT03196999
The Trauma Recovery and Empowerment Model for Treating Post-Traumatic Stress Disorder in Women
Dartmouth-Hitchcock Medical Center
NCT00183716
Effectiveness of Peer-Delivered Trauma-Specific Treatment
University of New Mexi
NCT02081417
Cognitive-Behavioral Conjoint Therapy (CBCT) Project
VA Office of Research and Development
NCT02720016
ALTO-100 in MDD and/or PTSD
Alto Neuroscience
NCT05117632
A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-Traumatic Stress Disorder (PTSD)
Bionomics Limited
NCT04951076
The Family of Heroes: an Evaluation of an Online Educational Tool
Department of Veterans Affairs, New Jersey
NCT01554839
PTSD Training for PCPs in a Virtual World
San Francisco Veterans Affairs Medical Center
NCT03898271
A Randomized Controlled Trial of Meditation Compared to Exposure Therapy and Education Control on PTSD in Veterans
United States Department of Defense
NCT01865123
Examination of Glutamate and mGluR5 in Psychiatric Disorders
Yale University
NCT02727972
Brief Peer Supported webSTAIR Compared to Enhanced Wait List
Palo Alto Veterans Institute for Research
NCT04286165
Quantifying the Efficacy and Role of Service Dogs for Military Veterans With PTSD
University of Arizona
NCT03245814
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 2 | 22 |
| Phase 3 | 8 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Post Traumatic Stress Disorder Trial Landscape
146 indexed Post Traumatic Stress Disorder studies · 71 recruiting (49%).
Phase mix: 13 late (III/IV) vs 30 early (I/II).
Top sponsor: VA Office of Research and Development (19 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Post Traumatic Stress Disorder?
PlainTrial tracks 146 US clinical trials for Post Traumatic Stress Disorder, of which 71 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Post Traumatic Stress Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.