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NCT06273527 · ClinicalTrials.gov registry record · Phase 2

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

A Phase 2 study of Depression and Post Traumatic Stress Disorder, sponsored by University of California, San Diego.

Recruiting
Registry status
Phase 2
Development phase
128
Enrollment target
1
Study location

NCT06273527 is a Phase 2 study of Depression and Post Traumatic Stress Disorder that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 128 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06273527, a Phase 2 study of Depression and Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by University of California, San Diego.

RECRUITING
Registry status
Phase 2
Development phase
128 participants
Enrollment target
1
Study location

Study Summary

The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participants will be randomly assigned to one of two groups. Group 1 will receive a computer-based program that is designed as a cognitive training intervention and Group 2 will receive a similar computer-based exercise that researchers think will be less effective in training thinking skills (also known as a control or sham condition). Participants will be compared on cognitive performance and brain response during cognitive tasks from baseline to post-treatment.

Conditions Studied

Depression Post Traumatic Stress Disorder Anxiety Disorders

Interventions

  • BEHAVIORAL COGENT
  • OTHER Sham Program

Study Locations (1)

California

  • UC San Diego - San Diego

Trial Details

FieldValue
Enrollment Target 128 participants
Start Date 2024-10-01
Est. Completion 2027-08-01
Phase Phase 2

Sponsor

University of California, San Diego

775 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06273527

The ClinicalTrials.gov registry entry for NCT06273527 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 128 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (84% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which COGENT is the first listed.

NCT06273527 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06273527 about?

NCT06273527 is a clinical study titled "Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)". The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms. Participants will be randomly assigned to one of two groups. Group 1 will receive a computer-based program th...

What is the current status of trial NCT06273527?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 128 participants. The study started on 2024-10-01. Estimated completion is 2027-08-01.

What conditions does trial NCT06273527 study?

This clinical trial studies the following conditions: Depression, Post Traumatic Stress Disorder, Anxiety Disorders.

What interventions are being tested in trial NCT06273527?

The interventions under investigation include: COGENT (BEHAVIORAL), Sham Program (OTHER).

Who is sponsoring clinical trial NCT06273527?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06273527 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.