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NCT05790239 · ClinicalTrials.gov registry record · Phase 2
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
A Phase 2 study of Post Traumatic Stress Disorder, sponsored by Stephen Robert Marder.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 2
- Study locations
NCT05790239 is a Phase 2 study of Post Traumatic Stress Disorder that is actively recruiting participants, run by Stephen Robert Marder. The registered enrollment target is 40 participants, below the 1,117-participant average among 144 other Post Traumatic Stress Disorder trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT05790239, a Phase 2 study of Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Stephen Robert Marder.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
This randomized, double-blind, single-site phase II 2-arm study will investigate the safety and preliminary efficacy of MDMA-assisted therapy compared with low dose d-amphetamine-assisted therapy on the severity of PTSD symptoms in participants aged 18 years and older with PTSD of at least moderate severity.
Conditions Studied
Interventions
- DRUG d-amphetamine
- DRUG 3,4-methylenedioxymethamphetamine
- BEHAVIORAL Therapy
Study Locations (2)
California
- VA Greater Los Angeles Healthcare System, Westwood campus - Los Angeles
- West Los Angeles Veteran Affairs - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-03-01 |
| Est. Completion | 2026-03 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05790239
The ClinicalTrials.gov registry entry for NCT05790239 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,117-participant average among 144 other Post Traumatic Stress Disorder trials with a reported enrollment target (96% lower). The listed sponsor is Stephen Robert Marder, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 3 interventions - of which d-amphetamine is the first listed.
NCT05790239 reports 2 study locations spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT05790239 about?
NCT05790239 is a clinical study titled "MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder". This randomized, double-blind, single-site phase II 2-arm study will investigate the safety and preliminary efficacy of MDMA-assisted therapy compared with low dose d-amphetamine-assisted therapy on the severity of PTSD symptoms in participants aged 18 years and older with PTSD of at least moderate ...
What is the current status of trial NCT05790239?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2025-03-01. Estimated completion is 2026-03.
What conditions does trial NCT05790239 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT05790239?
The interventions under investigation include: d-amphetamine (DRUG), 3,4-methylenedioxymethamphetamine (DRUG), Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT05790239?
This trial is sponsored by Stephen Robert Marder, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05790239 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.