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Glaucoma clinical trials
39 of 94 indexed Glaucoma trials are currently recruiting.
94 US clinical trials · 39 currently recruiting
Glaucoma is the subject of 94 registered US clinical trials on ClinicalTrials.gov, 39 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is Stanford University, running 8 of these trials.
The research picture
Glaucoma has 94 registered US clinical trials, 39 of them open to new participants right now, about 41% of the total.
- 39
- recruiting participants now
- 41%
- of trials open to enrollment
- 16
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Stanford University
Active & Recent Trials
94 total, page 1 of 2
Village-Integrated Eye Worker Trial II
University of California, San Francisco
NCT03752840
Novel Glaucoma Diagnostics
Wills Eye
NCT00286637
The Glaucoma and Retinopathy Screening Study
Massachusetts Eye and Ear Infirmary
NCT06882356
Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers
University of Alabama at Birmingham
NCT06629649
Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2
University of Michigan
NCT06934577
Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
Glaukos Corporation
NCT07075718
Stem Cell Ophthalmology Treatment Study II
MD Stem Cells
NCT03011541
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)
SpyGlass Pharma
NCT07218783
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
SpyGlass Pharma
NCT07218796
Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices
State University of New York at Buffalo
NCT05523622
Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma
Glaukos Corporation
NCT06057051
A Trial of Hydrus Microstent Versus Goniotomy
Massachusetts Eye and Ear Infirmary
NCT06289491
Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension
Bausch & Lomb Incorporated
NCT07168902
Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial
University of Pennsylvania
NCT05924477
Automated Applanation Tonometry - Updated
Duke University
NCT07298356
Data Gathering for A10900
Optos
NCT07149740
Functional and Structural Imaging for Glaucoma
Oregon Health and Science University
NCT01957267
To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.
The New York Eye & Ear Infirmary
NCT07425496
Ocular Blood Flow Imaging for Glaucoma Assessment
University of Maryland, Baltimore
NCT05726058
Pilocarpine Use After Kahook Goniotomy
Montefiore Medical Center
NCT03933631
24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring
Smartlens
NCT06689696
Retinal Blood Flow and Autoregulation
University of Maryland, Baltimore
NCT05344274
Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications
University of California, Los Angeles
NCT04354545
A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients
Brian Shafer
NCT07076303
Hyperbaric Oxygen Therapy for Optic Neuropathies
Stanford University
NCT06128720
Perimetric Testing With Virtual Reality
Envision Health Technologies
NCT06549010
Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy
University of Maryland, Baltimore
NCT06993597
Community Based Treatment for (ComBaT) Glaucoma
University of Michigan
NCT06124521
Topical Insulin for Glaucoma
Stanford University
NCT05206877
Tolerability of an Anesthesia-free Tonometer Tip
Duke University
NCT06585423
Glaucoma Laser Assessment of Stability and Sustainability
Twin Cities Eye Consultants
NCT06963684
Eye Pressure Lowering Surgery
Oregon Health and Science University
NCT01931904
Electrical Stimulation for the Treatment of Glaucoma
Stanford University
NCT05626491
Electrical Stimulation for the Treatment of Optic Neuropathies
Stanford University
NCT05626426
The Role of Music in Enhancing Attention During Visual Field Exams for Pediatric Glaucoma Patients
Johns Hopkins University
NCT06971588
Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma
Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,
NCT07209410
Optimize Pediatric OCT Imaging
Duke University
NCT06139523
Electrical Stimulation for Vision Neuroenhancement in Glaucoma
Stanford University
NCT06685211
Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use
University of Miami
NCT07217678
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.
iSTAR Medical
NCT05024695
Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT)
Columbia University
NCT04271709
iStent Inject New Enrollment Post-Approval Study
Glaukos Corporation
NCT04624698
A Real-World Study of Interventional Clinical Outcomes in Patients With Open Angle Glaucoma and Other Chronic Eye Diseases
Interstat
NCT07216677
Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution
SpyGlass Pharma
NCT06120842
Safety Assessment of T4090 Eye Drops in Ocular Hypertensive or Glaucomatous Patients.
Laboratoires Thea
NCT05389267
Anterior Segment Optical Coherence Tomography Microstent Positioning
University of Utah
NCT06666751
Visual Field Analysis With Artificial Intelligence
Sight Intelligence Engineering Corporation
NCT06920290
Study of NT-501 Encapsulated Cell Therapy for Glaucoma Neuroprotection and Vision Restoration
Stanford University
NCT02862938
Dual Intravitreal Implantation of NT-501 Encapsulated Cell Therapy for Glaucoma
Stanford University
NCT04577300
A Study of Yutiq Steroid Insert During Glaucoma Tube Implant Surgery
Sanjay Asrani
NCT04918121
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 10 |
| Phase 3 | 5 |
| Phase 4 | 11 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Glaucoma Trial Landscape
94 indexed Glaucoma studies · 39 recruiting (41%).
Phase mix: 16 late (III/IV) vs 21 early (I/II).
Top sponsor: Stanford University (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Glaucoma?
PlainTrial tracks 94 US clinical trials for Glaucoma, of which 39 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Glaucoma?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.