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NCT06096740 · ClinicalTrials.gov registry record · NA
Psychotherapy Effects on Reward Processing in PTSD
A NA study of Post Traumatic Stress Disorder and PTSD, sponsored by University of Texas at Austin.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06096740: Recruiting NA study of Post Traumatic Stress Disorder and PTSD, sponsored by University of Texas at Austin.
NCT06096740 is a NA study of Post Traumatic Stress Disorder and PTSD that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 120 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06096740, a NA study of Post Traumatic Stress Disorder and PTSD, is actively recruiting participants, sponsored by University of Texas at Austin.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to identify how trauma-focused psychotherapy changes the function of brain circuitry in posttraumatic stress disorder (PTSD) and how this mediates improvements in the diminished ability to experience positive emotions following a traumatic or extremely stressful life event. In this instance, the investigators will be using cognitive processing therapy (CPT), a widely-utilized and evidence-based treatment for PTSD.
Primary Outcome
The changes in deoxyhemoglobin driven by localized changes in brain blood flow and blood oxygenation associated with individual trial-by-trial reinforcement learning computational model parameters at the time of choice valuation (expected reward value during safe contexts and expected reward value during threat contexts) and choice outcome (reward prediction errors during safe contexts and reward prediction errors during threat contexts).
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Processing Therapy
Study Locations (1)
Texas
- Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600 - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2024-06-01 |
| Est. Completion | 2029-05-01 |
| Phase | NA |
What NCT06096740 shows while recruiting
NCT06096740 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower).
The record links to 6 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 1 intervention - of which Cognitive Processing Therapy is the first listed.
NCT06096740 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06096740 about?
NCT06096740 is a clinical study titled "Psychotherapy Effects on Reward Processing in PTSD". The purpose of this study is to identify how trauma-focused psychotherapy changes the function of brain circuitry in posttraumatic stress disorder (PTSD) and how this mediates improvements in the diminished ability to experience positive emotions following a traumatic or extremely stressful life eve...
What is the current status of trial NCT06096740?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2024-06-01. Estimated completion is 2029-05-01.
What conditions does trial NCT06096740 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, PTSD, Anhedonia, Diminished Pleasure, Chronic PTSD.
What interventions are being tested in trial NCT06096740?
The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT06096740?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06096740 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06096740's enrollment target sits among peer trials
120 96th of 262 higher than 158 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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