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NCT06577636 · ClinicalTrials.gov registry record · Phase 2
Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder
A Phase 2 study of PTSD and Post Traumatic Stress Disorder, sponsored by Stanford University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 42
- Enrollment target
- 1
- Study location
NCT06577636 is a Phase 2 study of PTSD and Post Traumatic Stress Disorder that is actively recruiting participants, run by Stanford University. The registered enrollment target is 42 participants, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06577636, a Phase 2 study of PTSD and Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 42 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to test whether anesthesia-induced dreaming can help alleviate symptoms of PTSD in an (1) open-label trial (Phase I) and (2) double-blind, randomized controlled trial (Phase II) in a non-surgical setting. The investigators predict that inducing and sustaining a dream state prior to emergence from anesthesia will result in reduced symptoms of PTSD. Participants will undergo EEG-guided propofol anesthesia during which they will be either (1) receiving deep sedation leading to loss of responsiveness, designed to elicit dream reports upon emergence (Dream Protocol), and/or (2) light sedation without loss of responsiveness, designed to elicit non-dream experiential reports while responsive (e.g., simple imagery, sounds, thoughts, bodily sensations, hypnagogic-like experiences) (Non-Dream Protocol). The investigators will then investigate whether the deep-sedation Dream Condition is associated with a larger reduction in PTSD symptoms than the light-sedation Non-Dream Condition.
Conditions Studied
Interventions
- PROCEDURE Propofol anesthesia
Study Locations (1)
California
- Stanford University - Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2025-07-21 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06577636
The ClinicalTrials.gov registry entry for NCT06577636 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 302-participant average among 154 other PTSD trials with a reported enrollment target (86% lower). The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with PTSD appearing as the primary indexed condition, and to 1 intervention - of which Propofol anesthesia is the first listed.
NCT06577636 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT06577636 about?
NCT06577636 is a clinical study titled "Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder". The goal of this study is to test whether anesthesia-induced dreaming can help alleviate symptoms of PTSD in an (1) open-label trial (Phase I) and (2) double-blind, randomized controlled trial (Phase II) in a non-surgical setting. The investigators predict that inducing and sustaining a dream state ...
What is the current status of trial NCT06577636?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2025-07-21. Estimated completion is 2026-12.
What conditions does trial NCT06577636 study?
This clinical trial studies the following conditions: PTSD, Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT06577636?
The interventions under investigation include: Propofol anesthesia (PROCEDURE).
Who is sponsoring clinical trial NCT06577636?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06577636 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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