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NCT06477796 · ClinicalTrials.gov registry record · NA

Improving Sleep in Veterans With the Polytrauma Clinical Triad

A NA study of Chronic Pain and Traumatic Brain Injury, sponsored by VA Office of Research and Development.

Recruiting
Registry status
NA
Development phase
96
Enrollment target
1
Study location

NCT06477796 is a NA study of Chronic Pain and Traumatic Brain Injury that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 96 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06477796, a NA study of Chronic Pain and Traumatic Brain Injury, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
NA
Development phase
96 participants
Enrollment target
1
Study location

Study Summary

The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain. Veterans with the PCT are medically complex, often refractory to conventional therapies, and suffer from additional related chronic sequela. Notably, sleep disturbances and cognitive impairment, which the investigators hypothesize are significant contributing factors to these functional impairments and an impediment toward rehabilitation. Thus, the investigators' research aims to intervene "at the level of sleep", and by improving sleep, improve these interconnected, disabling, and difficult to treat enduring complexities associated with the PCT - ultimately to improve Veteran quality of life, functional independence, and restorative function. The investigators predict that the proposed intervention, morning bright light therapy, which is cost-effective, rapidly deployable and home-based, will be effective in improving sleep and overall PCT symptom management, thereby, resulting in a measurable and impactful improvement in quality of life.

Interventions

  • DEVICE Morning Bright Light Therapy
  • DEVICE Negative Ion Generator

Study Locations (1)

Oregon

  • VA Portland Health Care System, Portland, OR - Portland

Trial Details

FieldValue
Enrollment Target 96 participants
Start Date 2025-05-01
Est. Completion 2028-09-29
Phase NA

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT06477796

The ClinicalTrials.gov registry entry for NCT06477796 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (88% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Chronic Pain appearing as the primary indexed condition, and to 2 interventions - of which Morning Bright Light Therapy is the first listed.

NCT06477796 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.

Frequently Asked Questions

What is clinical trial NCT06477796 about?

NCT06477796 is a clinical study titled "Improving Sleep in Veterans With the Polytrauma Clinical Triad". The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain. Veterans with the PCT are medically complex, often refractory to conventional therapies, and suffer from addi...

What is the current status of trial NCT06477796?

This trial is currently recruiting. It is a NA study. The enrollment target is 96 participants. The study started on 2025-05-01. Estimated completion is 2028-09-29.

What conditions does trial NCT06477796 study?

This clinical trial studies the following conditions: Chronic Pain, Traumatic Brain Injury, Post Traumatic Stress Disorder.

What interventions are being tested in trial NCT06477796?

The interventions under investigation include: Morning Bright Light Therapy (DEVICE), Negative Ion Generator (DEVICE).

Who is sponsoring clinical trial NCT06477796?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06477796 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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