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NCT01627301 · ClinicalTrials.gov registry record · NA
Sympathetic Overactivity in Post-traumatic Stress Disorder
A NA study of Post Traumatic Stress Disorder and Prehypertension, sponsored by Emory University.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT01627301: Recruiting NA study of Post Traumatic Stress Disorder and Prehypertension, sponsored by Emory University.
NCT01627301 is a NA study of Post Traumatic Stress Disorder and Prehypertension that is actively recruiting participants, run by Emory University. The registered enrollment target is 120 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01627301, a NA study of Post Traumatic Stress Disorder and Prehypertension, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress. This study will evaluate whether 8 weeks of daily DGB therapy or transcutaneous vagus nerve stimulation (tVNS) therapy improves SNS activity at rest and during stress.
Primary Outcome
MSNA is assessed with microneurography where a tungsten microelectrode inserted in the nerve records sympathetic nerve activity.
Conditions Studied
Interventions
- DEVICE Transcutaneous Vagal Nerve Stimulation (tVNS)
- DEVICE Device-Guided Breathing (DGB)
- DEVICE Sham DGB
- DEVICE Sham tVNS
Study Locations (1)
Georgia
- Atlanta VA Medical Center - Decatur
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2012-07 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT01627301 shows while recruiting
NCT01627301 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (82% lower).
The record links to 2 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 4 interventions - of which Transcutaneous Vagal Nerve Stimulation (tVNS) is the first listed.
NCT01627301 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT01627301 about?
NCT01627301 is a clinical study titled "Sympathetic Overactivity in Post-traumatic Stress Disorder". Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress. This...
What is the current status of trial NCT01627301?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2012-07. Estimated completion is 2027-12.
What conditions does trial NCT01627301 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Prehypertension.
What interventions are being tested in trial NCT01627301?
The interventions under investigation include: Transcutaneous Vagal Nerve Stimulation (tVNS) (DEVICE), Device-Guided Breathing (DGB) (DEVICE), Sham DGB (DEVICE), Sham tVNS (DEVICE).
Who is sponsoring clinical trial NCT01627301?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01627301 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01627301's enrollment target sits among peer trials
120 96th of 262 higher than 158 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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